DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18749 and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_001027154.1	Gene:	CG18749 / 3771984	FlyBaseID:	FBgn0042182	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	219	Identity:	59/219 - (26%)
Similarity:	103/219 - (47%)	Gaps:	30/219 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   280 NTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGM-------LNSSDFGLSESVSGLKSEV 337
            |.......||..:|.|.:...|.::|.||.:...|.:.:       |..|.....::..|:||:|
plant    63 NDKDAELLRIGNVKPEVVSWSPRIIVLHDFLSPEECEYLKAIARPRLQVSTVVDVKTGKGVKSDV 127

  Fly   338 RTSKD---SHIVDA----KTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDFHEYTNTTRL 395
            |||..   :|:..:    :.:.:|:...:.:..|..:...::.|.....:..|||:  :.:|..|
plant   128 RTSSGMFLTHVERSYPIIQAIEKRIAVFSQVPAENGELIQVLRYEPQQFYKPHHDY--FADTFNL 190

  Fly   396 KQ-GDRIATVLFYLREVDSGGATVFP-------------MLNITVMPKKGSAVFWYNLHNSGAVN 446
            |: |.|:||:|.||.:...||.|.||             |..|:|.|.||.||.::::...|..:
plant   191 KRGGQRVATMLMYLTDDVEGGETYFPLAGDGDCTCGGKIMKGISVKPTKGDAVLFWSMGLDGQSD 255

  Fly   447 SKTLHTACPVISGSKYVLTKWINE 470
            .:::|..|.|:||.|:..|||:.:
plant   256 PRSIHGGCEVLSGEKWSATKWMRQ 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528
CG18749	NP_001027154.1	P4Hc	314..468	CDD:214780	49/181 (27%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	54/202 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920