Protein Alignment CG18749 and P4ha1

DIOPT Version :10

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_742059.2
• Gene: P4ha1 / 64475
• RGDID: 621000
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 151/529 - (28%)
• Similarity: 240/529 - (45%)
• Gaps: 102/529 - (19%)

  Fly    32 YAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSF 96
            :..|..::..|:..|.:||.:||.|:|..:.|...:::....:.|.......|.|.::|:|:|:|
  Rat    21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAF 85

  Fly    97 RLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMYFYDLKPEEL 161
            :|:.||:|.|.:.....:|..::  |.|.|..:.|:..|...|...|.:.:..|...|:|....:
  Rat    86 KLMKRLNTEWSELENLILKDMSD--GFISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNTI 148

  Fly   162 AAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEAWYNLSLTRFD----NIIEK-------- 214
            :.|||.|.... :.|||.||..||:...........|.|...:|.:.:    :.::|
  Rat   149 SKGNLPGVKHK-SFLTAEDCFELGKVAYTEADYYHTELWMEQALMQLEEGEMSTVDKVSVLDYLS 212

  Fly   215 YQVHKAW----ALLLAKNKQLTEAFQHFENKPEGIVASNEVIHFEGVLATTQNCT---------- 265
            |.|::..    ||||.|        :..|..||...|:..:::||.:::..::..
  Rat   213 YAVYQQGDLDKALLLTK--------KLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQ 269

  Fly   266 ---------AVVQKP--------------------SKKLHCRYNT-STTPFTRIAPLKMEELGLD 300
                     ||...|                    .|:|.|||:. :..|...:||.|.|:....
  Rat   270 KTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDK 334

  Fly   301 PYMVVFHDVIYDTEID--------------------GMLNSSDFGLSES--VSGLKSEVRTSKDS 343
            |.::.|||:|.|.||:                    |.|.::.:.:|:|  :||.:..|
  Rat   335 PRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYEDPV------ 393

  Fly   344 HIVDAKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDF---HEYTNTTRLKQGDRIATVL 405
                ...:|.|:.|:|||.:..::...:.|||:||.:..|.||   .|......|..|:||||.|
  Rat   394 ----VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWL 454

  Fly   406 FYLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINE 470
            ||:.:|.:|||||||.:..:|.||||:|||||||..||..:..|.|.||||:.|:|:|..||::|
  Rat   455 FYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHE 519

  Fly   471 LPQMFVTPC 479
            ..|.|..||
  Rat   520 RGQEFRRPC 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	36/132 (27%)
		P4Hc	314..468	CDD:214780	65/178 (37%)
P4ha1	NP_742059.2	P4Ha_N	24..155	CDD:462433	36/132 (27%)
		TPR	205..238		9/40 (23%)
		P4Hc	345..518	CDD:214780	67/182 (37%)