Protein Alignment CG18749 and p4ha2

DIOPT Version :9

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 144/525 - (27%)
• Similarity: 241/525 - (45%)
• Gaps: 99/525 - (18%)

  Fly    35 STMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLI 99
            ||.::..|:..|.:|:.:||.|::..:.:.:.::|...::...:....:|.|.|||:|:|:::|:
 Frog    26 STGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVDELSSRSTADPEGYLGHPVNAYKLV 90

  Fly   100 HRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMYFYDLKPEELAAG 164
            .|.:|.|.....  :.::::|.|.|.|....|:..||..|...|.|.:..:...|.|.|:.:|.|
 Frog    91 KRFNTDWSSLEN--LVLQDSAKGFIANFTFQREYFPTEEDETGAARALMRIQDTYKLDPDVIAKG 153

  Fly   165 NLAGYSQPGT----GLTAYDCLALGEFGVQNQKDDLAEAWYNLSLTRFDN----IIEKY------ 215
            .|     |||    .|:|.|...:|:....:........|...:|.:.|.    ::.|.
 Frog   154 KL-----PGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGEDAVVNKVDVLDYL 213

  Fly   216 --------QVHKAWAL---LLAKNKQLTEA------FQHFENKPEGIVASNEVIHFEGVLATTQN 263
                    .|.:|..|   |||.:.....|      |:..:.|.:..:..||..:.|.  ||.|
 Frog   214 SYTVFQLGDVPRALELTKRLLALDPNHDRAVNNLKYFEKMQEKQKAELKQNESTNTES--ATRQ- 275

  Fly   264 CTAVVQKP-------------------------SKKLHCRY-NTSTTPFTRIAPLKMEELGLDPY 302
             ..|..:|                         .::|.||| |.:.:|:..::|:|:|:....|.
 Frog   276 -PGVYSRPLDYLPERDVYEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPR 339

  Fly   303 MVVFHDVIYDTEI--------------------DGMLNSSDFGLSESVSGLKSEVRTSKDSHIVD 347
            :|.:.:.:.|.||                    .|:|:.:::.:|      ||......|..::
 Frog   340 IVRYLNALSDEEIAKIKELAKPKLARATVRDPKTGVLSVANYRVS------KSAWLEENDDPVI- 397

  Fly   348 AKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDF---HEYTNTTRLKQGDRIATVLFYLR 409
             ..:|.|:..:|||:::.::...:.|||:||.:..|.||   .|.....||..|:|:||.|.|:.
 Frog   398 -ARVNLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDFSRKDEPDVFKRLGTGNRVATFLNYMS 461

  Fly   410 EVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINELPQM 474
            :|::|||||||.....:.||||:|||||||..||..:.:|.|.||||:.|||:|..||.:|..|.
 Frog   462 DVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYRTRHAACPVLVGSKWVSNKWFHERGQE 526

  Fly   475 FVTPC 479
            |:.||
 Frog   527 FLRPC 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	35/130 (27%)
		P4Hc	314..468	CDD:214780	62/176 (35%)
p4ha2	XP_012814344.2	P4Ha_N	27..113	CDD:400573	21/87 (24%)
		TPR repeat	166..201	CDD:276809	6/34 (18%)
		TPR repeat	206..236	CDD:276809	6/29 (21%)
		P4Hc	348..521	CDD:214780	64/180 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000