DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18749 and CG31021

DIOPT Version :9

Sequence 1:	NP_001027154.1	Gene:	CG18749 / 3771984	FlyBaseID:	FBgn0042182	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_733392.2	Gene:	CG31021 / 43638	FlyBaseID:	FBgn0051021	Length:	453	Species:	Drosophila melanogaster

Alignment Length:	476	Identity:	124/476 - (26%)
Similarity:	212/476 - (44%)	Gaps:	77/476 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRLHTSW 106
            :|.:|..|:.|::.|.:.|:.|.:|:...:.|.:.:..:...|.|.||.|||||||||..:|..|
  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDW 65

  Fly   107 RKWYQYAIK-VENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMYFYDLKPEELAAGNLAGYS 170
            ..|..|... |...|:..:|:   :...||.....::|.|.:|.|..||..:|.:|.|.:....|
  Fly    66 VGWQVYMEDLVAPEAVQKVES---LLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSSS 127

  Fly   171 QPGTGLTAYDCLALGEFGVQNQKDDLAEA-W-----YNLSLTRFDNIIE-----KYQVHKAWALL 224
               ..|:..||..|| ..:..::|.|..| |     :|.:|:|..::..     ::||::.....
  Fly   128 ---LHLSPLDCYHLG-LELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRWQVYRDLGRT 188

  Fly   225 LAK-NKQLTEAFQHFENKPEGIVASNEVIH----------------FEGVL-------ATTQNCT 265
            |.| |:|.  |:..:|:   .:..:::.:|                .|.:|       ...:.|.
  Fly   189 LLKLNRQC--AYDAYES---ALRLNSQNVHLMKEAGQMELFSLRDPMEPILDLQPKPTVLEKYCR 248

  Fly   266 AVVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSD------- 323
            ..|.:...:|.|..|.....|...||:|.|:|..||:::::...||:.||..:.|:.:
  Fly   249 GEVPRHQGRLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYERCPPNDR 313

  Fly   324 FGLSESVSGLKSEVRTSKDSHIVDAKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDFHE 388
            |.|...:||.     :..|.:....|.:|||:.||.|:. :..|.|.::.|.....|   ..|..
  Fly   314 FELKLGISGC-----SISDGYSPVLKRINERILDMAGVE-KTWDTFYIVEYAQLAPF---EPFKL 369

  Fly   389 YTNTTRLKQ------GDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNS 447
            :.|:|:..:      .|..|.|:.:|::|..|||...|..:|.|.||:|:.:..:.       |.
  Fly   370 FRNSTKFPKLNLMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITFE-------NE 427

  Fly   448 KTLHTACPVISGSKYVLTKWI 468
            :...|.||:|.|:..|:.|:|
  Fly   428 EHSTTICPIIEGTGLVMIKFI 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	40/124 (32%)
CG18749	NP_001027154.1	P4Hc	314..468	CDD:214780	44/166 (27%)
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	38/120 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.980