Protein Alignment CG18749 and PH4alphaNE1

DIOPT Version :10

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 157/528 - (29%)
• Similarity: 232/528 - (43%)
• Gaps: 83/528 - (15%)

  Fly    17 FINCQGFVNSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEM 81
            |:..||.:.|:    |.:|...|..||..|..|...|:..|..::.....:|..|..:.:|:...
  Fly    12 FLLAQGSLASD----YFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMA 72

  Fly    82 KSDYESYLGNPLNSFRLIHRLHTSWR----KWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQ 142
            .||.|:||.||:|.:||:.||||.|.    :....|.::..||      .|......|:..|::.
  Fly    73 ASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNA------TREYGLSYPSQEDVEG 131

  Fly   143 ACRGIHDLMYFYDLKPEELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEAWYNLSLTR 207
            |...:..|...|.|...::|.|.|.|... |:.::..||..||:...:.:..:..:.|...|:.|
  Fly   132 AALALVRLQSTYKLDVAQVAQGILNGVKY-GSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMER 195

  Fly   208 FDNIIEKYQVH---------------KAWALLLAKNKQLTEAFQ----------------HFENK 241
            ..........|               :|.|..|.:......||:                |..:|
  Fly   196 LRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLGDK 260

  Fly   242 ----PEGI------------VASNEVIHFEGVLATTQNCTAVVQK-PSKKLHCRYNTSTTPFTRI 289
                ||.|            ..|.|...:|.|      |...|.. ..::|.|||:....|:..:
  Fly   261 GTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKV------CRGEVHPIVRQELRCRYSRGNHPYRFL 319

  Fly   290 APLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSDFGLSES-VSGL------KSEVRTSK------ 341
            ||||:||..||||:..|||::...:|..:...:...:..| |:.|      ||..|.||
  Fly   320 APLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAY 384

  Fly   342 DSHIVDAKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDFHEYTNTTRLKQGDRIATVLF 406
            :||......|.: :.|.|||.....:...:.|||:|||:..|.||....|....::|:||||.:|
  Fly   385 ESHPTMVGMLRD-LKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIF 448

  Fly   407 YLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINEL 471
            ||.||:.||||.||.|:|.|.|:.|:.:||||||.|...:.:|.|..|||:.|||::...||:|:
  Fly   449 YLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIGNVWIHEV 513

  Fly   472 PQMFVTPC 479
            .|.|..||
  Fly   514 TQTFARPC 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	39/136 (29%)
		P4Hc	314..468	CDD:214780	62/166 (37%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..157	CDD:462433	39/136 (29%)
		P4Hc	341..511	CDD:214780	63/170 (37%)