Protein Alignment CG18749 and PH4alphaEFB

DIOPT Version :9

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 163/528 - (30%)
• Similarity: 253/528 - (47%)
• Gaps: 105/528 - (19%)

  Fly    38 ELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRL 102
            |:.:|||.|..|:.||:||::..:.|.|.::..:.:..||:.:...|..:|:.||:|::.|..||
  Fly    31 EMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDASHDITAYVSNPINAYLLTKRL 95

  Fly   103 HTSWRKWYQYAIKVENNALGH------IENARLMRKML--PTSSDLQQACRGIHDLMYFYDLKPE 159
            .|.||       :|| |.:.|      ::|....|.:|  |:..||..|...:..|...|.|...
  Fly    96 TTDWR-------QVE-NLMEHDVGTDFLQNITQYRSLLKFPSDEDLNGAAVALLRLQDTYQLDTS 152

  Fly   160 ELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEAWYNLSLTRF-------------DNI 211
            .:|.|.|.|. |..|.:::.||..||.....|........|.|.::.|.             .:|
  Fly   153 SVARGKLNGI-QYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADI 216

  Fly   212 IE--KYQVHKAWAL--LLAKNKQLTEAFQHFE-------------------NKPEGIVASNEVIH 253
            :|  .:..:|...:  .|....:|.:...|.|                   .|.:|...::|:..
  Fly   217 LEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMPK 281

  Fly   254 FEGVLATTQNCTAVVQ---------------KPS----KKLHCRYNTSTTPFTRIAPLKMEELGL 299
            .:  |...::..|:..               |||    :.|.|||.|:..||.|:.|||:||:..
  Fly   282 SD--LPVAKSDPAIFDMTERRAYEMLCRGELKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHA 344

  Fly   300 DPYMVVFHDVIYDTEID--------------------GMLNSSDFGLSESVSGLKSEVRTSKDSH 344
            |||:|::||.:||:|||                    |.|.::::.:|:|     :.::|.:|..
  Fly   345 DPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANYRISKS-----AWLKTQEDRV 404

  Fly   345 IVDAKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDF---HEYTNTTRLKQGDRIATVLF 406
            |   :|:.:|..|||||.|:.::...::|||:|||:..|.||   .|......|..|:|||||||
  Fly   405 I---ETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDFARKEEQRAFEGLNLGNRIATVLF 466

  Fly   407 YLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINEL 471
            |:.:|:.||||||..|:..:.||||:|.||.|||..|..:.:|.|.||||::|:|:|..|||:|.
  Fly   467 YMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNKWIHER 531

  Fly   472 PQMFVTPC 479
            .|.|..||
  Fly   532 GQEFRRPC 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	41/135 (30%)
		P4Hc	314..468	CDD:214780	67/176 (38%)
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	41/135 (30%)
		P4Hc	356..529	CDD:214780	70/180 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461818
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.890