Protein Alignment CG18749 and CG4174

DIOPT Version :9

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_001034031.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 122/498 - (24%)
• Similarity: 223/498 - (44%)
• Gaps: 73/498 - (14%)

  Fly    13 LSACF-INCQGFVNSNPKK-SYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMS 75
            ::||. ...:|.|.|.|:. .:|.|:...:.||::::..|:||:.|.|.||.....:.|::
  Fly     8 VTACLGFQVKGEVVSAPESYDFAISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAI---- 68

  Fly    76 RENMEMKSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDL 140
            |::.|:....::...|.:..::::..||..|.::::...|  :..|..|..::::....|||.|.
  Fly    69 RQSEELLKSTKTSPRNLIYGYKVLRHLHNDWPQYFRLLKK--DLGLEQIAVSQMLLTQQPTSVDF 131

  Fly   141 QQACRGIHDLMYFYDLKPEELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEAWYNLSL 205
            :::...:|.|...|:|....:..|.:....:.....:|.:||.||...:..:..:.:|.|..|:|
  Fly   132 EESMGAMHRLQTVYNLDSYAMTEGFIDDKDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELAL 196

  Fly   206 TRF-DNIIEKYQVHKAW------ALLLAKNKQLTEAFQ--------------------------H 237
            ..: ||:..:....|.|      ..|:..||.|...|:                          |
  Fly   197 YHYDDNVSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSINPNHTYMLTQLPKLKH 261

  Fly   238 FENKPEGIVASNEVIHFEGVLATTQNCTAVVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPY 302
            .::.|..:....:|...:     .:.|:...::.|..|.||| ...|||.::||||||||.:.||
  Fly   262 LQSNPAKLTKPKKVFQLQ-----KEICSKRYRRKSGVLVCRY-VDWTPFLKLAPLKMEELSMKPY 320

  Fly   303 MVVFHDVIYDTEIDGMLNSSDFGLS--ESVSGLKS----EVRTSKDSHIVDAKTLNERVTDMTGL 361
            :.:|:..:...:|:.:.|.|...|.  |.:||..|    .:.||  .|.| .:.:||.:..:||.
  Fly   321 ISIFYGFLGQKDIEVLKNVSRPKLQRIEHLSGNCSCKIGNLSTS--LHDV-VRKVNELILGITGF 382

  Fly   362 SMEMSDPFSLINYGLGGHFILHHDFHEYTNTTRLKQGDRIATVLFYLREVDSGGATVFPMLNITV 426
            .::.:....:||||:.|::          |....|..:: |....:|.....||..|||..::.|
  Fly   383 PLKGNQMLEVINYGIAGNY----------NPEEPKIHNK-ANAFIFLSNAGKGGEIVFPSRHLKV 436

  Fly   427 MPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWIN 469
            .|:|||.:.|.||..|      .::..||::.|:.:|..|.:|
  Fly   437 RPRKGSMLVWENLKKS------LIYHQCPILKGNMWVANKVLN 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	29/130 (22%)
		P4Hc	314..468	CDD:214780	44/159 (28%)
CG4174	NP_001034031.2	P4Ha_N	33..157	CDD:285528	28/129 (22%)
		TPR repeat	169..197	CDD:276809	8/27 (30%)
		TPR repeat	202..245	CDD:276809	8/42 (19%)
		2OG-FeII_Oxy	<362..470	CDD:304390	35/127 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461881
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990