DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18749 and CG34041

DIOPT Version :9

Sequence 1:	NP_001027154.1	Gene:	CG18749 / 3771984	FlyBaseID:	FBgn0042182	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	347	Identity:	73/347 - (21%)
Similarity:	165/347 - (47%)	Gaps:	49/347 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KLTFIGFLSACFINCQGFV-----NSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFN 65
            ::.||...|||.::. |.:     .||.:..::.|..:::.:|::::.:|..|:.|:..|:.|..
  Fly   227 QMEFIVMKSACILSV-GLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLK 290

  Fly    66 LMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLM 130
            .::.:|||::..:::.:.|..:...:|:.|:.|||.:.:.|..|..:.    ....|..|.|.||
  Fly   291 TIDEALIDLATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFL----QEDPGKDELASLM 351

  Fly   131 --RKMLPTSSDLQQACRGIHDLMYFYDLKPEELAAGNLAG----YSQPGTGL------------- 176
              :|.|||.:|:.:.|.||..::..|.:..:::|.|.:.|    |......|
  Fly   352 SIKKYLPTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHL 416

  Fly   177 -TAYDCLALGEFGVQNQKDDLAEAWYNLSLTR------FDNIIEKYQVHKAWALLLAKNKQLTEA 234
             :..||:||.:..::.:..:.::.|.|::::.      :|.|:....::...|.:..|.:..|.|
  Fly   417 MSLRDCVALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLA 481

  Fly   235 FQHFE----NKPEG--IVASNEVIHFEGVLATTQNCTAVVQ------KPSKKLHCRYNTS-TTPF 286
            .:..|    :.|..  ::...:.:.:..:|...::....::      :.:..|:|.|:|. .|.:
  Fly   482 LETVEFALKSNPRNAQLIRMQKRLSYHILLGPPKSPKLNIENNDYRLRKNGSLYCFYDTKIRTFY 546

  Fly   287 TRIAPLKMEELGLDPYMVVFHD 308
            :.:||:|.|.|.:||.::::|:
  Fly   547 SLLAPIKAEVLFIDPLVILYHE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	34/132 (26%)
CG18749	NP_001027154.1	P4Hc	314..468	CDD:214780
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	34/132 (26%)
		TPR repeat	452..491	CDD:276809	7/38 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462007
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840