Protein Alignment CG18749 and PH4alphaNE3

DIOPT Version :9

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_651814.1
• Gene: PH4alphaNE3 / 326114
• FlyBaseID: FBgn0051017
• Length: 481
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 144/491 - (29%)
• Similarity: 243/491 - (49%)
• Gaps: 50/491 - (10%)

  Fly    17 FINCQGFVNSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEM 81
            |...:..:|...::.:..:....|.|::::.||:|||..|.:.:..|.:.::|...::.:.....
  Fly     2 FCKVESTLNWESRQEFLDTESAKMDLMQLDVELIDNLMNYAEKIDEKASQLKRLAQELRQPLHSA 66

  Fly    82 KSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKM--LPTSSDLQQAC 144
            |...|.||||||:||.||..::..||    |..:.....:|..|...|.||:  ||...|.::|.
  Fly    67 KGREEEYLGNPLHSFPLIRHMYQDWR----YLEEFMKKPVGEEEIQFLRRKLPELPWQVDTEEAS 127

  Fly   145 RGIHDLMYFYDLKPEELAAGNLAGYSQPGTGLTAYDCLALG----EFGVQNQKDDLAEAWYNLSL 205
            ..|..:...|.:.|.::|.|.:.......| |.|.||..:.    ::|...|    |..|..:|.
  Fly   128 VSIFRIAETYGMMPWDMANGLIDNVRFNST-LPALDCFEVAKMYFKWGYFKQ----ALQWITISK 187

  Fly   206 TR----FDNIIE-----KYQVHKAWALLLAKNKQLTEAFQHFENKPEGIVASNEVIHFEGVLATT 261
            .|    :..:.|     :..|....|..|.:..:..||.:...::|:  :|.|.:...:...|..
  Fly   188 ARMKEEYSGVYEVLGMNRQDVALLQARCLVELDRRDEAHEVLLDQPD--LADNSISLLDQFKANP 250

  Fly   262 QN---------------CTAVVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIY 311
            ..               |.:.......|||||||::|:.|..:|||||||:.|:|::||:||::.
  Fly   251 YEAIDSSPKLGEGYKRLCRSSFSPNPSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILP 315

  Fly   312 DTEIDGMLNSSDFGL------SESVSGLKSEVRTSKDSHIVDAKTLNERVTDMTGLSMEMSDPFS 370
            |.:|..::..::..|      .::.:..:|..||.....::|  :|.:|:.|:|||.:...:|.:
  Fly   316 DKDIQQLITLAEPLLKPTEMFDDNKNEARSSYRTPLGGPLLD--SLTQRMRDITGLQIRQGNPIN 378

  Fly   371 LINYGLGGHFILHHDFHEYTNTTRLKQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVF 435
            :|.||.|..:..::||.:..|:.....|||:||.:|||.:...|||||||.||:.|..::|..:|
  Fly   379 IIKYGFGAPYTNYYDFFKKRNSESKGFGDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLF 443

  Fly   436 WYNLH-NSGAVNSKTLHTACPVISGSKYVLTKWINE 470
            ||||: ::..:...|:|.||||..|||:|:|.||:|
  Fly   444 WYNLNGDTHDMEPTTMHAACPVFHGSKWVMTAWIHE 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	39/132 (30%)
		P4Hc	314..468	CDD:214780	55/160 (34%)
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	39/127 (31%)
		P4Hc	316..478	CDD:214780	57/163 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461727
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.890