Protein Alignment CG18749 and P4ha3

DIOPT Version :10

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 555
• Identity: 155/555 - (27%)
• Similarity: 240/555 - (43%)
• Gaps: 143/555 - (25%)

  Fly    31 SYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSR---ENMEMKSDYESYLGNP 92
            :::|.| .:.:.|..|..|:..|:.|::.       .|..|.|::|   :.:.:..|.:..:.||
Mouse    28 TFSALT-SVARALAPERRLLGTLRRYLRG-------EEARLRDLTRFYDKVLSLHEDLKIPVVNP 84

  Fly    93 LNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLMR-------KMLPTSSDLQQACRGIHDL 150
            |.:|.||.||.:.||...        ::|...||.|.::       :.||...||:.|.|.:..|
Mouse    85 LLAFTLIKRLQSDWRNVV--------HSLEATENIRALKDGYEKVEQDLPAFEDLEGAARALMRL 141

  Fly   151 MYFYDLKPEELAAGNLAGYSQPGTG--------------LTAYDCLALG---------------- 185
            ...|.|..:.||    .|..|..||              |||.||..:|
Mouse   142 QDVYMLNVKGLA----RGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKPSCGSRSLQVAYDTG 202

  Fly   186 ---------------------------EFGVQNQKDDLAEAWYN-------LSLTRF------DN 210
                                       |..:::..|.||.|.:.       |||:|.      ||
Mouse   203 DYYHAIPWLEEAVSLFRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDN 267

  Fly   211 -----IIEKYQVHKAWALLLAKNKQLTEAFQHFENKPEGIVASNEVIH------FEGVLATTQNC 264
                 .:.||:      .|||:|.....|        |..:....|.|      :||:..|..:.
Mouse   268 KRMARNVLKYE------RLLAENGHQMAA--------ETAIQRPNVPHLQTRDTYEGLCQTLGSQ 318

  Fly   265 TAVVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSDFGLSES 329
            ....|.||  |:|.|.|:::|:..:.|.:.|.:.|.|.:.::||.:.|.|...:...::..|..|
Mouse   319 PTHYQIPS--LYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQRS 381

  Fly   330 V--SG---LKSEVRTSKDSHIVDA-----KTLNERVTDMTGLSME--MSDPFSLINYGLGGHFIL 382
            |  ||   |:.|.|.||.:.:.|.     .||:.|:..:|||.::  .::...::|||:|||:..
Mouse   382 VVASGEKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEP 446

  Fly   383 HHDFHEYTNTT---RLKQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGA 444
            |.| |..:.::   |:|.|:|:||.:.||..|::||||.|...|.:|...|.:|:||:|||.||.
Mouse   447 HFD-HATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGE 510

  Fly   445 VNSKTLHTACPVISGSKYVLTKWINELPQMFVTPC 479
            .:..|||..|||:.|.|:|..|||:|..|.|..||
Mouse   511 GDGDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPC 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	36/142 (25%)
		P4Hc	314..468	CDD:214780	62/168 (37%)
P4ha3	XP_006508007.1	P4Ha_N	31..158	CDD:462433	38/146 (26%)
		P4Hc	363..535	CDD:214780	64/172 (37%)