Protein Alignment CG18749 and P4ha2

DIOPT Version :9

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_006532515.1
• Gene: P4ha2 / 18452
• MGIID: 894286
• Length: 557
• Species: Mus musculus
• Alignment Length: 549
• Identity: 151/549 - (27%)
• Similarity: 241/549 - (43%)
• Gaps: 123/549 - (22%)

  Fly    32 YAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSF 96
            :..|...:..|:..|.:||.:||.|:...:.|...::.....|........:|.|.||.:|:|::
Mouse    25 FFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNAY 89

  Fly    97 RLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMYFYDLKPEEL 161
            :|:.||:|.|.....  :.:::.:.|.:.|..:.|:..||..|...|.|.:..|...|.|.|:.:
Mouse    90 KLVKRLNTDWPALGD--LVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTI 152

  Fly   162 AAGNLAGYSQPGTG----LTAYDCLALGEFGVQNQKDDL-AEAWYNLSLTRFD---------NII 212
            :.|.|     |||.    |:..||..||. ...|:.|.. ...|....|.:.|         :::
Mouse   153 SRGEL-----PGTKYQAMLSVDDCFGLGR-SAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLV 211

  Fly   213 EKY---------QVHKAWAL---LLAKNKQLTEA------FQHFENKPEGIVASNEVIHFEGVLA 259
            ..|         .:|:|..|   ||:.:.....|      |:....:..|...||:.   :..||
Mouse   212 LDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQT---DAGLA 273

  Fly   260 TTQNCTAVVQKPS-------------------------KKLHCRY-NTSTTPFTRIAPLKMEELG 298
            |.:|   :.::|:                         |||.||| :.:..|...|||.|.|:..
Mouse   274 TQEN---LYERPTDYLPERDVYESLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEW 335

  Fly   299 LDPYMVVFHDVIYDTEID--------------------GMLNSSDFGLSESVSGLKSEVRTSKDS 343
            ..|::|.::||:.|.||:                    |:|..:.:.:|:| |.|:.:     |.
Mouse   336 DSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKS-SWLEED-----DD 394

  Fly   344 HIVDAKTLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDF---------------------- 386
            .:|  ..:|.|:..:|||:::.::...:.|||:||.:..|.||
Mouse   395 PVV--ARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNY 457

  Fly   387 -HEYTNTTRLKQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTL 450
             .|.....||..|:|:||.|.|:.:|::|||||||.|...:.||||:|||||||..||..:.:|.
Mouse   458 SDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTR 522

  Fly   451 HTACPVISGSKYVLTKWINELPQMFVTPC 479
            |.||||:.|.|:|..||.:|..|.|:.||
Mouse   523 HAACPVLVGCKWVSNKWFHERGQEFLRPC 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528	34/130 (26%)
		P4Hc	314..468	CDD:214780	64/196 (33%)
P4ha2	XP_006532515.1	P4Ha_N	28..157	CDD:369820	34/130 (26%)
		P4Hc	348..541	CDD:214780	66/200 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910