DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18749 and C14E2.4

DIOPT Version :9

Sequence 1:	NP_001027154.1	Gene:	CG18749 / 3771984	FlyBaseID:	FBgn0042182	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001359861.1	Gene:	C14E2.4 / 182616	WormBaseID:	WBGene00015773	Length:	311	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	52/204 - (25%)
Similarity:	92/204 - (45%)	Gaps:	36/204 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 LKMEELGLDPYMVVFHDVIYDTEIDGMLNSSDFGLSESVSGLK-SEVRTSKD------------- 342
            ::||.|...|.:|::.||....::...|        |.:..|| :|.:..:|
Worm    81 VRMEILSWSPPLVIYRDVFSKKQVSDYL--------ELLKNLKMNEQKVVRDDGEIAYSTYRQAN 137

  Fly   343 -------SHIVDAKTLNERVTDMTGL-SMEMSDPFSLINYGLGGHFILHHDFHEYTNTTRL---- 395
                   || .:|::|.:..|.:..: ..:.::..|.::|..|||:.||.||..:.|....
Worm   138 GTITPAHSH-AEAQSLMDTATQLLPVFDFQYTEQISALSYIKGGHYALHTDFLTFANAEDSNRHF 201

  Fly   396 -KQGDRIATVLFYLREVDSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISG 459
             :.|:|:||.:...::.:.||.|:||.|........|.|..|:|.:.:....:|:||..||:.:|
Worm   202 GEMGNRLATFIMVFKKAEKGGGTLFPQLGNVFRANPGDAFLWFNCNGNLEREAKSLHGGCPIRAG 266

  Fly   460 SKYVLTKWI 468
            .|.:.|.||
Worm   267 EKIIATIWI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..166	CDD:285528
CG18749	NP_001027154.1	P4Hc	314..468	CDD:214780	43/180 (24%)
C14E2.4	NP_001359861.1	P4Hc	100..276	CDD:214780	45/185 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770