Protein Alignment CG18749 and phy-2

DIOPT Version :10

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_502317.1
• Gene: phy-2 / 178170
• WormBaseID: WBGene00004025
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 151/510 - (29%)
• Similarity: 242/510 - (47%)
• Gaps: 83/510 - (16%)

  Fly    38 ELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRL 102
            :|..:|..|.::...:..|::..:.:.:.:.|...:....|...:|....::.||:|::.||.||
 Worm    24 DLQHMLGAEKDVTTIIDQYIEAERARLDDLRRYAHEYVHRNAHAESVGPEFVTNPINAYLLIKRL 88

  Fly   103 HTSWRKWYQYAIKVENNA---LGHIENARLMRKM-LPTSSDLQQACRGIHDLMYFYDLKPEELAA 163
            .|.|:|...  |.:.|.|   |.:|.:.|:..:: .|...||..|...:..|...|.|...:|:.
 Worm    89 TTEWKKVEN--IMLNNKASTFLKNITDNRVRSEVKFPGEEDLSGAATALLRLQDTYSLDTLDLSN 151

  Fly   164 GNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDL-AEAWYNLSLTRFDN----IIEKYQV--HKAW 221
            |.:.| .:....|:.:|...:|. ...||||.. ...|..::|.:.:|    .||::::  :.|:
 Worm   152 GIIGG-EKVSNKLSGHDTFEVGR-SAYNQKDYYHCLMWMQVALVKIENENPPTIEEWEILEYLAY 214

  Fly   222 AL--------LLAKNKQLTE-AFQH---------FENKPEG---------IVASNEVIHFEGVL- 258
            :|        .|:..|:|.: |..|         :|:..:|         ||  |:.:.::|::
 Worm   215 SLYQQGNVRRALSLTKRLAKIAPNHPRAKGNVKWYEDMLQGKDMVGDLPPIV--NKRVEYDGIVE 277

  Fly   259 --ATTQNCTA----VVQKPSKKLHCRYNTSTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEID- 316
              |....|..    |..|...||.| |.....||.::||:|:|.|..||..|:|.:||:|:||:
 Worm   278 RDAYEALCRGEIPPVEPKWKNKLRC-YLKRDKPFLKLAPIKVEILRFDPLAVLFKNVIHDSEIEV 341

  Fly   317 -------------------GMLNSSDFGLSESVSGLKSEVRTSKDSHIVDAKTLNERVTDMTGLS 362
                               |.|..:.:.:|:| :.||.::     ..::|  .:|.|:.|.|.|:
 Worm   342 IKELASPKLKRATVQNSKTGELEHATYRISKS-AWLKGDL-----DPVID--RVNRRIEDFTNLN 398

  Fly   363 MEMSDPFSLINYGLGGHFILHHDF--HEYTNTTR-LKQGDRIATVLFYLREVDSGGATVFPMLNI 424
            ...|:...:.|||||||:..|.||  .|..|..: |..|:||||||||:.:.:.||||||..|..
 Worm   399 QATSEELQVANYGLGGHYDPHFDFARKEEKNAFKTLNTGNRIATVLFYMSQPERGGATVFNHLGT 463

  Fly   425 TVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINELPQMFVTPC 479
            .|.|.|..|:|||||...|..:.:|.|.||||:.|.|:|..|||:|..|.|..||
 Worm   464 AVFPSKNDALFWYNLRRDGEGDLRTRHAACPVLLGVKWVSNKWIHEKGQEFTRPC 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	32/133 (24%)
		P4Hc	314..468	CDD:214780	64/176 (36%)
phy-2	NP_502317.1	P4Ha_N	21..156	CDD:462433	32/133 (24%)
		P4Hc	335..508	CDD:214780	66/180 (37%)