Protein Alignment CG18749 and p4ha1

DIOPT Version :10

• Sequence 1: NP_001027154.1
• Gene: CG18749 / 3771984
• FlyBaseID: FBgn0042182
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: XP_031761963.1
• Gene: p4ha1 / 100490484
• XenbaseID: XB-GENE-987760
• Length: 526
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 155/523 - (29%)
• Similarity: 238/523 - (45%)
• Gaps: 97/523 - (18%)

  Fly    32 YAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSF 96
            :..|...::.||..|.:||.:||.|:|..:.|...:::....:.........|.|.|||:|:|:|
 Frog    20 FFTSIGHMIDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGYLGHPVNAF 84

  Fly    97 RLIHRLHTSWRKWYQYAIKVENNAL-----GHIENARLMRKMLPTSSDLQQACRGIHDLMYFYDL 156
            :|:.||:|.|       :|:||..|     |.|.|..:.|:..|...|...|.:.:..|...|:|
 Frog    85 KLMKRLNTEW-------VKLENLILKDISDGFISNLTIQRQYFPNDEDQTGAAKALLRLQDTYNL 142

  Fly   157 KPEELAAGNLAGYSQPGTGLTAYDCLALGEFGVQNQKDDLAEAWYNLSLTRFD----NIIEK--- 214
            ..:.::.|||.|.... |.|||.||..||:....:......|.|...:|::.|    :.::|
 Frog   143 DTDTISKGNLPGVKHK-TSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMV 206

  Fly   215 -----YQVHKAWALLLAKNKQLTEAFQHFENKPEGIVASNEVIHF-------------EGVLATT 261
                 |.|::...|    :|.||...:..|..||....:..:.|.             ||....|
 Frog   207 LDYLSYAVYQQGDL----DKALTLTKRSLELDPEHQRGNGNLRHIMSKESNKSSSSPSEGAELRT 267

  Fly   262 QN---------------C----TAVVQKPSKKLHCRY-NTSTTPFTRIAPLKMEELGLDPYMVVF 306
            :.               |    ..:..:..|:|.||| :....|...::|.|.|:....|.:|.:
 Frog   268 RKGRPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQEDEWDKPRIVRY 332

  Fly   307 HDVIYDTEID--------------------GMLNSSDFGLSES--VSGLKSEVRTSKDSHIVDAK 349
            ||:|.|.||.                    |:|.::.:.:::|  :||.:..|          ..
 Frog   333 HDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPV----------VA 387

  Fly   350 TLNERVTDMTGLSMEMSDPFSLINYGLGGHFILHHDF---HEYTNTTRLKQGDRIATVLFYLREV 411
            .||.|:..:|||.|..::...:.|||:||.:..|.||   :|.....:|..|:|:||.|||:.:|
 Frog   388 RLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPHFDFLRKYEPDAFKKLGTGNRVATWLFYMSDV 452

  Fly   412 DSGGATVFPMLNITVMPKKGSAVFWYNLHNSGAVNSKTLHTACPVISGSKYVLTKWINELPQMFV 476
            ::|||||||.:...|.||||:|||||||..||..:..|.|.||||:.|:|:|..|||:|..|.|.
 Frog   453 EAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQEFR 517

  Fly   477 TPC 479
            .||
 Frog   518 RPC 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18749	NP_001027154.1	P4Ha_N	35..168	CDD:462433	41/137 (30%)
		P4Hc	314..468	CDD:214780	64/178 (36%)
p4ha1	XP_031761963.1	P4Ha_N	23..154	CDD:462433	41/137 (30%)
		NrfG	181..>244	CDD:443378	14/66 (21%)
		P4Hc	337..510	CDD:214780	66/182 (36%)