DRSC/TRiP Functional Genomics Resources

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Protein Alignment Msp300 and EVPLL

DIOPT Version :9

Sequence 1:NP_001188695.1 Gene:Msp300 / 3771968 FlyBaseID:FBgn0261836 Length:13540 Species:Drosophila melanogaster
Sequence 2:NP_001138599.1 Gene:EVPLL / 645027 HGNCID:35236 Length:301 Species:Homo sapiens


Alignment Length:358 Identity:75/358 - (20%)
Similarity:123/358 - (34%) Gaps:103/358 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly 12355 ETLSRIMQ--RNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHLKRVPHLKHRLDA 12417
            ||..|:.|  .|.|..:.:.    ::|:..:.|     :||| ..|:..::.:.:...|||    
Human    14 ETQKRLQQDRLNSEQSQALQ----HQQETGSSL-----KEAE-VLLKDLFLDVDKARRLKH---- 64

  Fly 12418 MIQQLDQGEQQSKALQEQ-QQELARHCDDALATAM-----RMEQASIGQRI-SNLRAALK--TWQ 12473
              .|.::.|:..:.|.|: .||.|.:|  ||...|     |..|..:|.|. :...|.|:  .|.
Human    65 --PQAEETEKDIEQLHERVTQECAEYC--ALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVWA 125

  Fly 12474 GF-----LQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLG 12533
            |.     ..|..|.....:||..:...|.|.|...........||:...:         .|.:.|
Human   126 GHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVV---------ARAEPG 181

  Fly 12534 AQVSALESLTVTQEELKECISPHDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQI 12598
            ..|.||:..|.....|.|     ..:.|.|::|      :||....|.:....|        :..
Human   182 QPVHALQGCTWQLSALAE-----QQRRILQQDW------SDLMADPAGVRREYE--------HFK 227

  Fly 12599 RYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYS 12663
            :::.:||                     ||:..|||:.....::||                   
Human   228 QHELLSQ---------------------EQSVNQLEEDGKRMVELR------------------- 252

  Fly 12664 EPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKI 12696
            .|.| ..:|...::|...||....|...:.|::
Human   253 HPAV-GPIQAHQEALKMEWQNFLNLCICQETQL 284

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Msp300NP_001188695.1 SPEC 17..220 CDD:238103
SPEC 9546..9732 CDD:295325
sbcc 11187..12008 CDD:129705
SMC_prok_B 11614..12442 CDD:274008 22/89 (25%)
SPEC 11994..12156 CDD:295325
SPEC 12374..12564 CDD:295325 46/203 (23%)
Lipase_chap 12376..12529 CDD:281297 37/166 (22%)
SPEC 12703..12923 CDD:238103
SPEC 12816..13032 CDD:295325
SPEC 13196..13374 CDD:238103
KASH 13484..13540 CDD:287506
EVPLLNP_001138599.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 18..41 5/26 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..166 10/47 (21%)
SPEC 193..>292 CDD:295325 26/152 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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