Protein Alignment Msp300 and pleca

DIOPT Version :9

• Sequence 1: NP_001188695.1
• Gene: Msp300 / 3771968
• FlyBaseID: FBgn0261836
• Length: 13540
• Species: Drosophila melanogaster
• Sequence 2: XP_021323775.1
• Gene: pleca / 567639
• ZFINID: ZDB-GENE-030131-8984
• Length: 4790
• Species: Danio rerio
• Alignment Length: 5549
• Identity: 1004/5549 - (18%)
• Similarity: 1834/5549 - (33%)
• Gaps: 1787/5549 - (32%)

  Fly  3026 PISEEPKKVVEPEKIPEEPKKPAYAGLPVDESSSSWMDVLDEPMNFSDDEEEPVPEPLKEETVVK 3090
            |:|:|..|           ||....|...:|.        ||.....|:.:|..    |||..:.
Zfish    93 PLSQEKHK-----------KKKEKLGNKTEEE--------DEKKEGKDENKEEG----KEEKTIT 134

  Fly  3091 EVVEDKPIVEVSIVDDSKTITTVTT-------------TTTTTETISELPISEEPKKVVEPEKIP 3142
            ....:|..::|:|...  |:|:.:.             .:.:.|:.|:|..|..|...: |..:|
Zfish   135 VRKRNKKHLKVTIAPG--TVTSASAGQVMSGGRRRMLERSASEESASDLSTSPFPGDTL-PWNLP 196

  Fly  3143 EEPKKPAYAGLPVDESSSSWMDVLDEPMNFS----DDEEEPVPEPLKEETVVEKIVEE-KPIVEV 3202
            :..:        |..|.|:..|||| |...:    .||.:.|.:....:.|.:.:|:. |...:.
Zfish   197 KHQR--------VKRSKSASGDVLD-PAERAVIRIADERDRVQKKTFTKWVNKHLVKHWKAEAQR 252

  Fly  3203 SVVDDSKTITTVTTTTTTTETISELPIPEETKKVVEPEKKPEEPKKPAYAGLPVDESSSSWMDVL 3267
            .:.|..:.:.......:..|.:|...:|.| :.||...:.|.|..:
Zfish   253 HITDLYEDLRDGHNLISLLEVLSGETLPRE-RDVVRNSRLPREKGR------------------- 297

  Fly  3268 DEPMNFSDDEEEPVPEPLKEETVVKEVVEEKPIVEVSVVDDS------KTITTVTTTTTTTETIS 3326
               |.|         ..|:...:..:.::.:.:..|::.:|.      |....:..|......||
Zfish   298 ---MRF---------HKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS 350

  Fly  3327 ELPISEEPKKVEEPEKIP--EEPKKPAYAGLPVDESSSSWMD----------------------- 3366
            ::.::.:...:...||:.  .:.....|.||..|..::||.|
Zfish   351 DIQVNGQSDDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHKHRPNLIDINKVYR 415

  Fly  3367 -----VLDEPMNFS----------DDEEEPVPEPVKEETVVKEVVEEKPIVEV--SVVDDSKTIT 3414
                 .|::..:.:          |.|:..||.|           :||.|:..  |:.|....:.
Zfish   416 QTNLENLEQAFSIAERDLGVTRLLDPEDVDVPHP-----------DEKSIITYVSSMYDVMPRVP 469

  Fly  3415 TVTTTTTTTETISELPIPEEPK-----------KVVEPEKKAEPSSFDEP-------MNFSDDEE 3461
            .|.......|.  ||...|..:           .|:..|::..|||::|.       :.|. :.|
Zfish   470 DVRDGVKANEL--ELRWQEYYELVTMLLQWIRHHVIVFEERKFPSSYEEIEVLWRQFLKFK-ETE 531

  Fly  3462 EPVPEPLKEET-LVEEVVEPIVESSVVDESKTITTVTTTIVTSTNQTNTLEEENSLPAPAE---- 3521
            .|..|..|..: |:.:..|..|::..|........:.............||.|..|.:..|
Zfish   532 LPAKETDKNRSKLIYKSFEGAVQAGQVKVPPNYHPIDVEKEWGRLHVAILEREKLLRSEFERLER 596

  Fly  3522 -PQIISNVVDDVSQLEKPLEGPIDTWSSVLEDTISNTGNIGYTS--TLSADAPEFTPSYLRHTFS 3583
             .:|:|.|     |:|          |.|.|:.::....:..|.  .|||..|      ::|...
Zfish   597 LQRIVSKV-----QME----------SGVCEEQLNQVETLLQTDIRLLSAGKP------IQHASD 640

  Fly  3584 DQTHTFLANERIYNEFIPRNRPEQTIGPHQKPKKAKPSKRQNKKVEIREKIIDVQPAQEINIVEP 3648
            .:|..                                :|.:|.   ||....|||..::...::.
Zfish   641 IETDL--------------------------------NKAENM---IRYLFNDVQLLKDGRHLQA 670

  Fly  3649 VQIVEEV----ENVWNMNRDGKSYADVLLNSGVTGDDVPSTEL-HKEIPHKTDIVKTKAQEPKKK 3708
            .|:...|    |.:.|:    :|..::.|.||||...||.|:: ..:|.|    |:|..|.| ::
Zfish   671 EQMYRRVYRLHERLVNL----RSEFNLRLKSGVTLSQVPMTQVPMTQISH----VQTLQQSP-QR 726

  Fly  3709 SKPEKRQA--EKVIELSSASIESEKSKPNSDSEQSKPTTESELSK-----PTTESSK----EPSS 3762
            .:|:..:.  :.:.:|.|...|:::....::..:..|:.||:|..     .:.|..|    ...:
Zfish   727 VRPDLDEVTLKYIQDLLSWVEENQRRIEGAEWGEDLPSVESQLGSHRGLHQSIEEFKYKIDRARA 791

  Fly  3763 DERDVSSTS-----------ELTWSALVQRPGEWSDSTVNKKQTSHTAV--TTKETHRQKEKEEP 3814
            ||..::..|           :|.::.|:..    |.:.:......|..|  .|||.....||||.
Zfish   792 DENQLTPVSKGAYREYLGKLDLQYAKLLTS----SKTRLRSLDQLHAFVVAATKELMWLNEKEEE 852

  Fly  3815 K---------KTTKAKKTKKS--------KKPVVDPVSTTSE----DEQPETVPEPVEAMPAPIE 3858
            :         ....|||...|        ::..|:.|..|.:    |..|  ..:.:||..|.::
Zfish   853 EVNYDWSDRNSNMTAKKDNYSGLMRDLEQREKRVNNVQMTGDKLLKDGHP--ARKTIEAFTAALQ 915

  Fly  3859 SKPEPEVVQKLESSNAFSWASLVKRPGEWIDNTV----THIK--TAVTP-LPDVKEPIKKDKKPQ 3916
            ::                |:        ||....    ||:|  ||... ..||||...:.||.:
Zfish   916 TQ----------------WS--------WILQLCCCIETHLKENTAYFQFFSDVKEAEDRMKKME 956

  Fly  3917 KPKKQK-ATKKPTPVALPEDEVSSEPSEEIVVECEVEEKETKSIKNTE----NAFSWASLVKKPG 3976
            ...|:| ...:...|...||          :::..|||||..:...|.    |..:...:..||.
Zfish   957 DTMKKKYVCDRSITVTRLED----------LLQDAVEEKEQLNEFKTHLEGLNRRAKTIIQLKPR 1011

  Fly  3977 EWVDDIASRKKPVEIIHEEPK---EVHPRKE-RKISKPQPKPQSENTTKRNNKKETREPVVVHST 4037
            .....|.. |.||:.:.:..:   .||...| ..::..||.......:..|.........:|..|
Zfish  1012 NPAQPIKG-KLPVQAVCDFKQMEITVHKGDECALVNNSQPYKWKVRDSSGNEAVVPSICFIVPPT 1075

  Fly  4038 SEES-DVVEVLEPTNEN-TITWAKIASQIDHMTDLKPKAKQETKPKQGE-------RVKE-QIRF 4092
            ::|: ||...|:.:.:. .:.|.|:...:..:...:...:..|......       ||:| ::..
Zfish  1076 NKEAVDVSSGLDGSQQRLMVLWQKLHVDMKSLLSWQYLMRDITLINSWNFIMFKTLRVEEYRLTL 1140

  Fly  4093 DRIEKHPKDHAISSDLSQQKGDSG--------HSWSSVVSH---------QVTDFIEAESIKPVP 4140
            ..:|:|.:  |...| ||..|..|        :|::....|         |....|:.:|.....
Zfish  1141 KNLEQHYQ--AFLRD-SQDSGLFGADDRMQAENSYNKATQHYDNLLRSVEQEPALIQKDSTSGEQ 1202

  Fly  4141 KKSVKKSSGNTQPKIAPKLEEPLQEPVQKDVESTPLMPWSEIIDDGLDDVVVERKSWKELIEDEI 4205
            .:||.||.......:..:||         ..||..:....:::|........:|.:.::.::.|:
Zfish  1203 DESVCKSYITQIKDLRLRLE---------GCESRTVNRLRQMVDKEPLKACTQRATEQKKVQTEL 1258

  Fly  4206 EIPLPHENGEKANIDKIIETIQEIQSTSEEKPN--------------------------NESKTI 4244
            |       |.|.::||::|..:.:.:||::..:                          ::.|||
Zfish  1259 E-------GIKKDLDKVVEKSEAVLATSQQSSSAPVLRSEIDITQKKMEHVYGLSSVYLDKLKTI 1316

  Fly  4245 TTVTTTTLSTESISESVTPMEPKKVAEPVPEPLKEETLVEEV----VEEKPIVEVSVVDDSKTIT 4305
            ..|..:|...|.|..                  |.|..:.||    |.||.| |.|.....|..:
Zfish  1317 DLVIRSTQGAEDILN------------------KYENQLREVNKVPVNEKEI-EASQTQLQKLRS 1362

  Fly  4306 TVTTTTTTTETISELPIPEEPKKVVELEKK------PEEPKKPAYAGLPVDDSTNSW-------- 4356
            .......|.:.:.     ||.::..|:.|:      ..:.:...|..| |.:....|
Zfish  1363 EAEGKQATFDRLE-----EELQRATEVNKRMSQLHSERDVELEHYRQL-VGNLRERWQAVFAQIE 1421

  Fly  4357 -----MDVLDEPMNFSDDEEEPVPEPVKEETVVQEVVEEKPIVEVSVVDDSKTITTVTTTTTNTE 4416
                 :|:|:..|....:..:.:...:.:....|:.:...||      ..||.:....|
Zfish  1422 LRQRELDLLNRQMQAYRESYDWLIRWIADAKQRQDKLHAVPI------GGSKGLQEQLT------ 1474

  Fly  4417 TISELPIPEEPKKVVELEKKPEEPKKPAYAGLPVDDS---TNSWMDVLDEPMNFSDDEE------ 4472
                    :|.|.:.|:||..::          |:|.   ...::|.:       .|.|
Zfish  1475 --------QEKKLLEEIEKNKDK----------VEDCQKFAKGYIDAI-------KDYELQLVTY 1514

  Fly  4473 ----EPIPEPQKE---ESLVKEVVEEKPIVEVSVVDDSKSITTVTTTTTTTETISEIAIPEEPTK 4530
                |||..|.|:   ||...::::|              ..|:.|..:...|:|...|    ..
Zfish  1515 KALVEPIASPLKKAKMESASDDIIQE--------------YVTLRTRYSELMTLSSQYI----KF 1561

  Fly  4531 VVEPEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSDDEEEPVPEPLKEETVVEEVVEEKPI 4595
            ::|.:::.:                                :||...|.||||       |.|.:
Zfish  1562 IIETQRRLQ--------------------------------DEEKAAEKLKEE-------ERKKM 1587

  Fly  4596 VEVSV-VDDSKTITTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAYAGLPVDDSTNSW 4659
            .|:.. ::..|.:         .||        ..|.:.:.|::..|.|      ..:.|..:..
Zfish  1588 AEMQAELEKQKQL---------AET--------HAKAIAKAEQEANELK------TKMKDEVSKR 1629

  Fly  4660 MDVLDEPMNFSDDEEEPVPEPLKE-ETVVEEVVEEKPIVEVSFVDDSKSITTVTTTTTTTETISE 4723
            .||..:    |:.::..:...|:| :|:.|:.::.|          |:.:.....:.|..|  .|
Zfish  1630 QDVAVD----SEKQKHNIQRELQELKTLSEQEIKAK----------SQQVEEALLSRTRIE--EE 1678

  Fly  4724 LPIPEEPKKVVEPEKKPEEPKKPAYAGLPVDESSSSLMDVLDEPMNFSDDEEEPVPEPVKEETLV 4788
            :.|.....:....:|...|.:........||         .|:..|.:.:|.|.:.:.|.|||..
Zfish  1679 IHIIRLQLETTMKQKNTAETELLQLRAKAVD---------ADKLRNAAQEEAEKLRKQVAEETQK 1734

  Fly  4789 KEVVEEKPIVEVSVVDDSKSITTVTTTTTTTETISELPIPEEPKKVVEPEKKPEEPKKPAYAGLP 4853
            |...|                                   ||.|:..|.||...:.||.|...|
Zfish  1735 KRKAE-----------------------------------EELKRKSEAEKDAAKEKKKALEDL- 1763

  Fly  4854 VDDSSNSWMDVLDEPMNFSDDEEE-----PIPEPLKEETVVEEVVEIKPIVEVSVVDDSKTITTV 4913
                         |......:|.|     ...|..::..|||||.  |......:......:|..
Zfish  1764 -------------EKFKLQAEEAERHLKQAELEKQRQIQVVEEVA--KKTAATQLESKQVALTAR 1813

  Fly  4914 TTTTITTETISELPISEE----PKKVVEPEKKPEEPKKPAYAGLPVDDSTNSWMDVLDEPMNFSD 4974
            ...::..|.:..:.:.||    .|:..|.:|..|:.:|          ...:|....:|.:....
Zfish  1814 LEESLKNEQVMVIQLQEEAEHLKKQQAEADKAREQAEK----------ELETWRQKANEALRLRL 1868

  Fly  4975 DEEEPVPEPVKEETLVEEVVEEKPIVEVSVVDDSKTITTVTTTTTTTETISEPVISEQPKKTVEP 5039
            ..||   |..|:....||..::|        :::|.                  .:::..|..|.
Zfish  1869 QAEE---EANKKTAAQEEAEKQK--------EEAKR------------------EAKKRAKAEEA 1904

  Fly  5040 VKKPEESTEVE----PKPLSSNIWELHSSYADVLRHTVDFISLEKNNVEVPTESNLGK---VPTV 5097
            ..|.:|:.|:|    .|.......:..::..:::|...||...|:....:..|....|   ...|
Zfish  1905 ALKQKEAAEMELGNQRKMAEETAKQKLAAEQELIRLRADFEHAEQQRTVLDDELQRLKNDVNSAV 1969

  Fly  5098 KEPAKLPEPLI------------KTKAKKEKPLKKEKGAKLLTPKDEVLPIERESAKDETKTSWS 5150
            |:..:|.|.||            |:||:||.....||..:||         |.|:||
Zfish  1970 KQKKELEEELIKVRKEMEILLQQKSKAEKETMSNTEKSKQLL---------ESEAAK-------- 2017

  Fly  5151 TMVENDFDDNVQTNILSADSTLWSSIVRQGAQEPITKMTQSADHDGKVLEPAFQNSQEINKFISQ 5215
                                      :|:.|:| .||:.       .|.|.|.:..|...:..::
Zfish  2018 --------------------------MRELAEE-ATKLR-------SVAEEAKKQRQIAEEEAAR 2048

  Fly  5216 ERSSTVIEKTKKQKSKKEKKHNKIESVVEVAL-EPYVDSTFMRDDPKTQQNAEIPSVLESLPIQP 5279
            :|:..  ||..|:|.....:..::::..|:|| |...::..::  .|.::......|||....|.
Zfish  2049 QRAEA--EKILKEKLTAINEATRLKTEAEIALKEKEAENDRLK--RKAEEEGYQRKVLEDQAAQH 2109

  Fly  5280 KSWSSIVSQTEVLPPTSIESKISQ--KAVDPH--RSKEV------QEFISKEQIFSTTVNADSKK 5334
            |.              :||.||.|  |:.|..  |.|::      |..:.:|:|....:|.: |.
Zfish  2110 KQ--------------AIEEKIGQLKKSSDTELDRQKKIVEETLKQRKVVEEEIHILKLNFE-KA 2159

  Fly  5335 PEDKKPLEEKPKK--------QKSK----------------KEKKTKVVEAPEPIVESAVPEAVV 5375
            ...|:.||.:.||        ||||                :|||.|..||....:::|..||..
Zfish  2160 SSGKQELELELKKLKGIADETQKSKAKAEEEAEKFRKLALEEEKKRKEAEAKVKQIQAAEEEAAR 2224

  Fly  5376 EPTVEVTFVEEPVVEVTTVVEE-------VTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEVTTN 5433
            :...    .:|.|..:..:.||       ...|.:.:...|.|.|  |..|.:...:|...|..|
Zfish  2225 QHKA----AQEEVGRLMKLAEEAKKQKEIAEKEAEKQVILVQEAA--QKCSAAEQKAQNVLVQQN 2283

  Fly  5434 ---VTETRFTEEPEDKKPLEEKPKKQKPKKEKKTKVVEAPEPIVESAVPEAVVEPTVEVTFVEEP 5495
               :.:.:..||.|..|.|.::.:|.|...||:..::.......|.....|..|...:....|:
Zfish  2284 KDSMAQDKLKEEFEKAKKLAQEAEKAKDNAEKEAALLHKKAEEAERQKKAAEAEAAKQAKAQED- 2347

  Fly  5496 VVEVTTVVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEITTNVTETRFTEEPEDK----KP 5556
                   .|::..|.:.|.:..:|                    ......:..:|.:.:    |.
Zfish  2348 -------AEKLRKEAEKEASRRAE--------------------AEAAALKLKQEADSEMAKYKK 2385

  Fly  5557 LEEKPKKQKSKKEKKTKVVEAPEPIVESAVPEAVVEPTVEVTFVEEPVVEVTTVVEEVTPETQPE 5621
            |.||..||||..|:  ::|:....:.|:...::|::            ||:..:.:||
Zfish  2386 LAEKTLKQKSSVEE--ELVKVKVQLDETDKQKSVLD------------VELKRLKQEV------- 2429

  Fly  5622 PTPVSEVAPSQPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLE-EKPKKQKPKKEK-KTKVVE 5684
                           |..:.|..:|...:::.:...|...|..|: ||..::..||:| .||
Zfish  2430 ---------------SDAIKQKAQVEDELSKVKIQMEDLLKLKLKIEKENQELMKKDKDNTK--- 2476

  Fly  5685 APEPIVESAVPEAVVEPTVEVTFVEEPVVEVTTVVEE---VTPETQPEPTPVSEVAPSQPLSWSS 5746
                                 ..:||....:..:.||   :..|.| |...:.::|.|.
Zfish  2477 ---------------------KLLEEEAENMKKLAEEAARLNIEAQ-EAARLRQIAESD------ 2513

  Fly  5747 IVSQTTEVTTNVTETR--FTEEPEDKKPSEEKPKKQK------------AKKEKKTKVVEAPEPI 5797
             :::..|:...:.|.:  ..:|....|...||.:|||            ||||.:.::.:..|..
Zfish  2514 -LAKQRELAEKMLEEKKQAIQEAAKLKAEAEKLQKQKDQAQVEAQKLLEAKKEMQQRLDQETEGF 2577

  Fly  5798 VESAVPEAVVEPTVEVTFVEEPVVEVTTVVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEV 5862
            .:|.  ||..:..:|:|...|.:....|.:.:...:.:.|.....:.|....:........|:|.
Zfish  2578 QKSL--EAERKRQLEITAEAEKLKVKVTQLSDAQSKAEEEAKKFKKQADEIKIRLQETEKHTSEK 2640

  Fly  5863 TTNVTE---TRFTEEPE---------DKKPLEEKPKKQKPKKEKKTKVVEAPEPIVESAVPEAVV 5915
            .|.|.:   .|...:.|         |.:..:||.||:....:|::|
Zfish  2641 HTVVEKLEVQRLQSKQEADGLHKAIADLEKEKEKLKKEAADLQKQSK------------------ 2687

  Fly  5916 EPTVEVTFVEEPVVEVTTVVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQT--TEVTTNVTETR 5978
                          |:..|.:|   :.|.|.|               |:.|:  .|..|.:.:.:
Zfish  2688 --------------EMANVQQE---QLQQEKT---------------ILQQSFFAEKETLLKKEK 2720

  Fly  5979 FTEEPEDK--KPLEEKPKKQ---KAKKEKKTKVVEAPEPIVESAVPEAVVEPTVEVTFVEEPVVE 6038
            ..||.:.|  |..|::.||.   ||::|::.|::|.....::||: :|.::...|
Zfish  2721 AIEEEKKKLEKQFEDEVKKAEALKAEQERQRKLMEEERKKLQSAM-DAAIKKQKE---------- 2774

  Fly  6039 VTTVVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEITTNVTETRFTEE---PEDKKPLEEK 6100
                .||.....|.|                         ..::.:.|..:|   .|:.|.|.||
Zfish  2775 ----AEEEMNGKQKE-------------------------MQDLEKKRIEQEKLLAEENKNLREK 2810

  Fly  6101 PKK-QKSKKEKKTKVVEAPEPIVESAVPEAVVEPTVEVTFVEEPVVEVTTVVEEVTPETQPEPTP 6164
            .:: |.|:|...||.:|    |....||             ||.:|::|.|  |.|.:.....|.
Zfish  2811 LQQLQSSQKASYTKEIE----IQTDKVP-------------EEELVQMTMV--ETTKKVLNGSTE 2856

  Fly  6165 VSEVAPSQPLSWSSI-----VSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKQKPKKEKKTKVVE 6224
            |..|....||::..|     .|:..|:.. :::..:.:..:.|..::|..|..|.|...|.|
Zfish  2857 VDGVKKDVPLAFDGIREKVPASRLHEIGV-LSKKEYDKLKKGKTTVQELSKNDKVKMCLKGK--- 2917

  Fly  6225 APEPIVESAVPEAVVEPTVEVTF---VEEPVVEVTTVVEEVTPETQPEPTPVSEVAPSQPLSWSS 6286
                   ..:...:|||..:::.   :::.::..:|.:  :..|.|.....:.:...::.||
Zfish  2918 -------DCIGGVIVEPNQKMSIYQALKDKMITQSTAI--MLLEAQAASGYIIDPIKNRRLS--- 2970

  Fly  6287 IVSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKQKSKKEKKTKVVEA-------PEPIVESAVPE 6344
                                      :.|..|......|..||::.|       .:|.....:
Zfish  2971 --------------------------VSESVKDGLIGPELHTKLLSAERAVTGFKDPFTGDTI-- 3007

  Fly  6345 AVVEPTVEVTFVEEPVVEVTT-------VVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEV 6402
            :|.|...:....|:..:::..       :::.|.....|.....::....:.|  |.|:|
Zfish  3008 SVFEAMKKGLITEDQAIKLLDCQYATGGIIDPVNSHHVPVQLACTQGQLDEDL--SKILS----- 3065

  Fly  6403 TTNVTETRFTEEPEDKKPLEEKPKKPKAKKE-KKTKVVEAPEPIVESSVPEAVVEPTVEVTFVEE 6466
                      ..|.|||...:    |..|.. ..:::::..:|..|:.:      |.:.:|  |:
Zfish  3066 ----------SPPADKKAFID----PNTKDSLTYSELLDQCKPDAETGI------PLLPIT--EQ 3108

  Fly  6467 PVVEVTTVVEEVKPETQPEPTSVSEVAPSQPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLEE 6531
            ......|..:|   ||:...:..:...|     :.....:|..:...:....|||  :.:|.|..
Zfish  3109 AAQSERTYSDE---ETKDVFSKANLTVP-----FGRFKGKTVTIWEVINSEYFTE--DQRKDLIR 3163

  Fly  6532 KPKKPKAKKEKKTKVV--------EAPEPI---VESSVPEAVVEPTVEVTFVEEPVVEVTTVVEE 6585
            :.|..|...||..::|        ...||.   :.||||.:             .::|...:.::
Zfish  3164 QYKTGKITVEKIIRIVITVVEDKENKKEPAFDGLRSSVPAS-------------ELLEAKVINKD 3215

  Fly  6586 VTPETQPEPTPVSEVAPSQPLSWSSIVSQATEVTTNVTETRFTEEPEDKKPLEEKPKKPKAKKEK 6650
            :..:.......:.:|:..:|      |.:|.:.|.::...:. |...:|..|.:..||.....|.
Zfish  3216 LFNKLHNGKATLKDVSELEP------VKKALKGTHSIAGVQI-ESTSEKMSLYDAMKKNLLGTEP 3273

  Fly  6651 KTKVVEAPEPIVESAVPEDVVEPTVEVTFVEEPVVEVTTVVEE------VTPETQQEPTPVSEVA 6709
            ...::||                .....|:.:||......|:|      |.||..:
Zfish  3274 ALNLLEA----------------QAGTGFIIDPVKNQKLTVDEAVKSGVVGPELHE--------- 3313

  Fly  6710 PSQPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKPKAKKEKKTKVVEAPEPIVESSV 6774
              :.||....|....:..|..|.:.|           |..:|...|||:..:::||      ...
Zfish  3314 --KLLSAERAVCGYKDPYTGKTVSLF-----------EAMQKDLIKKEQGVRLLEA------QLA 3359

  Fly  6775 PEAVVEPTVEVTFVEEPVVEVTTVVEEVTPETQPEPTPVSEVAPSQPLSWSSIVSQTTEVTTNVT 6839
            ...:::|  |.::             .:||:...:...::| ..:|.||..|.:| |..|..|..
Zfish  3360 TGGIIDP--EKSY-------------RITPDIAYKRGHLNE-EMNQNLSKPSDLS-TVYVDPNTQ 3407

  Fly  6840 E-TRFTEEPE----DKK------PLEEKPKKQKPKKEKKTKVVEAPEPIVESAVPEDVVEPTVEV 6893
            | ..:||..:    ||:      ||.||..|.|.           .||:.::...|::...|||:
Zfish  3408 EKVTYTELLKRCITDKQTGLPLIPLSEKAIKSKD-----------IEPVSDAQTKENLSHATVEL 3461

  Fly  6894 -------------------TFVEEPVVE------------------VTTVVEEVKPETQPEPTPV 6921
                               .|.||..:|                  |.:.|:|.:.:.|.....:
Zfish  3462 HSGLFKGRVITIWEIINSEYFTEEQRIEFIRQYRSGKITIEKLIKIVISTVDEKEKKRQDNFDGL 3526

  Fly  6922 SEVAPSQPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKQK-------------PKKE 6973
            ....|:..|..|.|:.:.|  ...:.:.:       |||.|.....::             .|.:
Zfish  3527 RGPVPASSLLESKIIDKDT--YDKILQGK-------KKPAEVSGSVKQYLQGSDCIAGVFFQKTK 3582

  Fly  6974 KKTKVVEA-PEPIVESAVPEDVVEPTVEVTFVEEPV-VEVTTVVEEVK-----PETQPEPTPVSE 7031
            :|..:.:| .:.::.|.....::|......::.:|: .|:.||.:.||     ||..
Zfish  3583 EKLSIYQAMKQKLLTSDTGMSLLEAQAATGYIIDPIRNEMFTVDDAVKAGIVGPEVH-------- 3639

  Fly  7032 VAPSQPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKQKPKKEKKTKVVEAP------ 7090
               .:.||....|:...:..|.           :|..|.:..:||...:|....:::|.
Zfish  3640 ---EKLLSAEKAVTGYKDPYTG-----------NKISLLQAMQKQLVLREHAIPLLDAQVATGGI 3690

  Fly  7091 -EPIVESAVPEDVV---------------EPTVEVTFVEEPVVEVTTVVEEVKPETQPEP----- 7134
             :|:....:|.||.               :||.::....:|..:.....:::|.....:|
Zfish  3691 IDPVNSHRLPNDVAIERGYFSKQLAKSFKDPTDDIKGFTDPNKDENVTYKQLKERCMTDPEFGVA 3755

  Fly  7135 -TPVSEVAPSQPLSWSSIV----SQTTEVTT--NVTETRFTEE--------------PEDKKPLE 7178
             .|:|:....:....|.:.    :||....|  ::...||..:              .|:|:.|.
Zfish  3756 LLPLSKAQTHEEAEKSYVYTEEQAQTDLANTQIDIPHERFAGKQVTLWEVMKSDMLPEEEKQRLL 3820

  Fly  7179 EKPKKQKPKKEKKT----KVVEAPEPI-VESAVPEDVVEPTVEV-TFVEEPVVEVTT--VVEEVK 7235
            |:.:..|..||:..    :::|..|.| .|.::..||:...|.: ......::::.|  ::::.|
Zfish  3821 EQYRSGKITKERMVIIIIEIIEQREIIKTEQSMSCDVIRRRVTIDELYRARIIDLETYNLLKQGK 3885

  Fly  7236 PETQPEPTPVSEV--APS--QPLSWSSIVSQTTEVTTNVTETRFTEEPEDKKPLEEKPKKQKPKK 7296
                   ..:.||  .||  |.|..:..:|       .|....:.     |..:.:..|:...|.
Zfish  3886 -------KAIREVMEMPSVKQYLFGTGSIS-------GVLSDNYA-----KVSIYQAMKRGLIKP 3931

  Fly  7297 EKKTKVVEAP-------EPI------VESAVPEDVVEPTVE---------VTFVEEPVV-EVTTV 7338
            :....::||.       :|:      |:.||.:.:|.|...         ||..::|.. :|.::
Zfish  3932 DIGIDLLEAQAATGFMIDPVKDELLTVDEAVRKGLVGPEFHDKLLSAERAVTGYKDPYSGKVISL 3996

  Fly  7339 VQEVKPETQPEPTPV----SEVAPSQPLSWSSIVSQTTEVTTNVTETRFTEEPE--DKKPLEEKP 7397
            .|.:|.:..||...:    ::||                       |....:||  .:.|::...
Zfish  3997 FQAMKKDLVPEDYAMKLLEAQVA-----------------------TGGLMDPEYYFRLPIDIAM 4038

  Fly  7398 KKQKPKKEKKTKVVEAPEPIVESAVPEDVVEPTVE--VTFV---------EEPVVEVTTVVE--- 7448
            ::....||...::.:      .|......::||.:  |::.         :|..:.:.::.:
Zfish  4039 QRGYMNKETSERISD------PSGDVNQFIDPTTDEKVSYASLLKRCKVDKESGLRLLSLADKRL 4097

  Fly  7449 -------EVTPETQPEPTSVSEVAPSQPLLWSSIVSQTT-EDVAEALIT--DVAEDQKPLMEKPK 7503
                   ::|||               .||.|.|:.|.| ..:.|..|:  |:::|.|..:|...
Zfish  4098 LFKGLRKQITPE---------------ELLRSQIIDQKTYTGLMEGTISVEDLSKDLKKYLEGIS 4147

  Fly  7504 KL-----KAGKEKKSKVQNVEESILESDVPLSVVEPIIGFTTVQKDVPPKTESHTFSWSSIVAQS 7563
            .:     :|.|::.|..|.::::::.......::|
Zfish  4148 SIAGVFVEATKDRLSVYQAMKKTMIRPGTAFELLE------------------------------ 4182

  Fly  7564 VEVPRTIPKHVESKTGGIQNFIAQEQNYSTVVNDSVK--------KPKPKKEKKIVQPIQQPTGE 7620
                      .::.||.|   |...:|....|.::||        |.|....::.|...:.|...
Zfish  4183 ----------AQAATGYI---IDPIKNLKMNVQEAVKMGVVGPEFKDKLLSAERAVTGYKDPYSG 4234

  Fly  7621 SVPVRKDHMREGVTKAVPEPQTLSWSSIVSHNIDLTPTFTENRVIEAV----DEINPDDSSSNQE 7681
            .|......|::|:.             :..|.|         |::||.    ..|:|::|.
Zfish  4235 KVISLFQAMKKGLI-------------LKDHGI---------RLLEAQIATGGIIDPEESH---- 4273

  Fly  7682 GELPIHV-------DERKR----KPKKDKKR--DQNIETSVVYEEIPETERVAVSSTPEFSIQLP 7733
             .||:.:       ||...    .|..|.|.  |.|.|.::.|.::  .||....:....|:.|
Zfish  4274 -RLPVEMAYKRGLFDEEMNGILTDPSDDTKGFFDPNTEENLTYLQL--MERCMTDTETGLSLLL- 4334

  Fly  7734 APTKPSVWSSSDTYAEVVKKSGYNNNTNIKYQKIEAREPIKSEPKH---TFVEVQTHEDLLEFPD 7795
                                        :|.:|.|.:...||..:.   ..|:.:|.:::..:
Zfish  4335 ----------------------------LKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVY-- 4369

  Fly  7796 PIIPAIERDEALEKPSQLSWKDLVDEDDVDPLE----SWHKGETDSVEIKTQKPIQERHSRVSVK 7856
                     ||..       |.|:|......|.    .|.:..|.|.:...:..|.:|.|.....
Zfish  4370 ---------EAYR-------KGLIDHQTYIELAEQECEWEEITTSSSDGVVKSMIIDRRSGRQYD 4418

  Fly  7857 PEIQITEVVTETQSQSETDQ---------EFLEITSKKRNRSRSRSQQSQASNIDEKHQKKKSKK 7912
            .:..|::.:.:   ||..||         ||.::.|...:..||||....:|          |..
Zfish  4419 IDDAISKGLID---QSALDQYRAGTLSITEFADMLSGNMSGFRSRSSSFGSS----------SSY 4470

  Fly  7913 PKNTVP--KAPAQQPTEAPEDVQP 7934
            |.:.||  |.||...|:..|:..|
Zfish  4471 PMSPVPSIKTPATTWTDPTEETGP 4494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msp300	NP_001188695.1	SPEC	17..220	CDD:238103
		SPEC	9546..9732	CDD:295325
		sbcc	11187..12008	CDD:129705
		SMC_prok_B	11614..12442	CDD:274008
		SPEC	11994..12156	CDD:295325
		SPEC	12374..12564	CDD:295325
		Lipase_chap	12376..12529	CDD:281297
		SPEC	12703..12923	CDD:238103
		SPEC	12816..13032	CDD:295325
		SPEC	13196..13374	CDD:238103
		KASH	13484..13540	CDD:287506
pleca	XP_021323775.1	SAC6	223..>462	CDD:227401	43/281 (15%)
		SPEC	736..830	CDD:197544	15/97 (15%)
		SPEC	831..1021	CDD:238103	50/226 (22%)
		SH3	1023..1068	CDD:327375	7/44 (16%)
		SMC_N	<1251..1797	CDD:330553	133/770 (17%)
		Neuromodulin_N	<1563..2182	CDD:331332	160/865 (18%)
		Neuromodulin_N	<1991..2836	CDD:331332	220/1125 (20%)
		Plectin	2950..2989	CDD:307019	9/67 (13%)
		PLEC	2986..3023	CDD:197605	7/38 (18%)
		Plectin	3025..3065	CDD:307019	5/41 (12%)
		Plectin	3240..3278	CDD:332473	7/38 (18%)
		Plectin	3277..3316	CDD:307019	10/65 (15%)
		PLEC	3314..3350	CDD:197605	11/46 (24%)
		Plectin	3352..3392	CDD:307019	8/61 (13%)
		Plectin	3566..3605	CDD:307019	4/38 (11%)
		Plectin	3604..3643	CDD:307019	9/49 (18%)
		PLEC	3641..3677	CDD:197605	9/46 (20%)
		Plectin	3679..3716	CDD:307019	5/36 (14%)
		Plectin	3937..3976	CDD:307019	8/38 (21%)
		Plectin	4012..4052	CDD:307019	8/62 (13%)
		Plectin	4141..4181	CDD:307019	5/39 (13%)
		Plectin	4180..4219	CDD:307019	11/81 (14%)
		PLEC	4217..4248	CDD:197605	6/30 (20%)
		Plectin	4255..4294	CDD:307019	10/43 (23%)
		Plectin	<4357..4385	CDD:307019	7/45 (16%)
		PLEC	4490..4523	CDD:197605	2/5 (40%)
		Plectin	4525..4564	CDD:307019
		Plectin	4601..4640	CDD:307019
		PLEC	4638..4675	CDD:197605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900