Protein Alignment Msp300 and pigs

DIOPT Version :10

• Sequence 1: NP_001188695.1
• Gene: Msp300 / 3771968
• FlyBaseID: FBgn0261836
• Length: 13540
• Species: Drosophila melanogaster
• Sequence 2: NP_572331.2
• Gene: pigs / 31596
• FlyBaseID: FBgn0029881
• Length: 977
• Species: Drosophila melanogaster
• Alignment Length: 1122
• Identity: 198/1122 - (17%)
• Similarity: 347/1122 - (30%)
• Gaps: 365/1122 - (32%)

  Fly 10084 RKTRKIIKRVVIIDGKEHITEEVVEEPEE-------VEITEEET-----APHINVNIVRTVDGKV 10136
            ||:.|||:.::.      .|::::....|       :|:.....     ||.: |.:.|.:|
  Fly   122 RKSLKIIECLLF------ETDDLIMRKNEKHVILCLLEVARRGAKFGMLAPML-VQMERQID--- 176

  Fly 10137 VSEEEFQRMMQEPGVLIEEVATDLQKPTA-----EPQQEVFDIESTQVTTTTRTTTATTQEQEQP 10196
                             .|:|.|::...|     ..|.:..:..::...|.| |.|.||.|.:..
  Fly   177 -----------------REIAADIKANGAGCSENGTQTDALETGNSSAATMT-TITTTTVETDLY 223

  Fly 10197 EQQTQPTTTETTKEAPVEL--PAPQV---------DVEQPVVVATTSPVHVPTADVVEPKDSSPT 10250
            :......|.:...:.||.:  |.||:         ::.:.:|...|.|...|...|.|.|.....
  Fly   224 DDSDDSETEDDGDQNPVLMYGPQPQIITNDLKSLDEMVRDLVEKCTCPSQFPMVRVSEGKYRIGD 288

  Fly 10251 STTAAVVDV--EAVVEDINEIW-PLEHHLKPTNIDFSQHVEELAAPAAVTAETEASMPVEEIWPT 10312
            :.....|.:  ..|:..:...| .|.|:|       .:|     .|....|:..:|:....|...
  Fly   289 TKVLIFVRILRSHVMVRVGGGWDTLSHYL-------DKH-----DPCRCRAQHRSSVAARLIPRQ 341

  Fly 10313 SPETGNSLTLEQYEFEPQSPHEESTKSDLVKPQETEPQVVAETKPE-------------GITTGS 10364
            ||.                 |..|...:|.|     .||:.|..|.             |..|||
  Fly   342 SPN-----------------HNPSNGIELHK-----AQVIFERSPPAARRVFNSPNCNGGPGTGS 384

  Fly 10365 ITITKTTTTITSSTEVPEETLVQNVPADEQQPPANKIKTDIQSFLEAEQT---LAAALKEQSSTP 10426
            ...|.........|.....:|..|......:.|     |..:.||..:..   :|:|
  Fly   385 SCGTGVVGVAVPPTLQNGHSLSPNSGKYRSRSP-----TPQRKFLNQQANGGGIASA-------- 436

  Fly 10427 TGASVAEDVQTQPEEIV----LEERTVEISTIKTEENQQEPVIVEEVKSLPVEPEPVEPELEEVA 10487
            ||:|......|...:::    |..|::..|..:..:.:::...::...|.|.........:||
  Fly   437 TGSSQTVTTDTSSGQLLGSPSLARRSMSPSPRRLIDMRKKQSSLDSYSSGPKSLPGYSCSMEE-- 499

  Fly 10488 IAIVEQTEEKPEEPVIEKQPASGPIDLRAATQLFISGEAAASTAPQKTFQISAPSLEDNGAGVLK 10552
                                |:|...:.:|.....||.|.:..|.::.......::.|||:
  Fly   500 --------------------ANGGSGVGSAAGGVSSGSAGSGVAGEQGGANKFENISDNGS---- 540

  Fly 10553 VVLGKESTNEEDTAAPTTGKVSMTIIETAAAPAADAKRRRKKKKRRDTKHEEELEQEQETEPEPV 10617
                 |.::|        |..|:.:|::.|             ::|::.|.:...::.|:.
  Fly   541 -----EISDE--------GYRSLGVIQSGA-------------QKRESLHSQASIEDAESN---- 575

  Fly 10618 AAVKEPEVSSDVPVSPEDSPRDTVRHESIVEISPDSDLSSIEIDTKVKIVEDAVVSSPSESPRTP 10682
              .:..:.|||..:||.|.|.:    ::..:|..:.||:.
  Fly   576 --ARLDQTSSDSQISPSDEPAE----KATTDILEEEDLNG------------------------- 609

  Fly 10683 MVELVIPTEVVELALVEDEEQQTTPRIPSPTEKSEVEQDIKSVQTSPQHQP-------KLDETAV 10740
                            :|.|:               :|:..||...||..|       ||.:...
  Fly   610 ----------------QDREE---------------DQEDYSVCDGPQSLPAILSGAHKLSDKFE 643

  Fly 10741 QTSLEVQPDNQENESQTLIVEITETEAQTTPRSEEQSVAVEISTTEIQTDVSGQPAETVEISSQT 10805
            |:.:.:..|           |||...|:|    |:||||          :..|.|...:....::
  Fly   644 QSGVFITDD-----------EITVDIAKT----EDQSVA----------NTMGNPTPNLSKIPRS 683

  Fly 10806 TVTTTIEKELQTTPKDSPRAPEAGSSDVVESLVQDLVKDMTTDLPVRTSEQSTVTETTTTTETHV 10870
            .:.....:.:     |:.....||.|      :|||........|..:.:|.......|...|..
  Fly   684 PLAQRRRRSI-----DNSTCGGAGGS------LQDLSSRSGLPAPAFSRKQPVYRSVRTRNSTGA 737

  Fly 10871 QTTTPEPREQTEVIKPETAHEETSTVELVQFADGEMQTTPPGDQQPASLDDSSLTATSISVSEPY 10935
            .||...|....:..:.....:.|:|        ...:||....::|
  Fly   738 TTTPVAPPRSRQATQLPMVRDVTNT--------WSGRTTGAPKRRP------------------- 775

  Fly 10936 ELEVKTTVAIPADSDTSVAEPTVYEYTQTMQLPKQEKKSK---------KDKKKKQKNVPEVEQQ 10991
                      |..:||.|| ||    ..|......|:..|         .:.::.:...|.....
  Fly   776 ----------PCTADTFVA-PT----NGTGPAGSFERNGKGRSSQILYDSNGRRVRSGAPGCTSS 825

  Fly 10992 L---PEDQQISVTVEIAPELLSESGIVVSTNQQIEDVPHVTPVVDTPIESEE---VETPKAQRVQ 11050
            |   |.....|  ..:|.:||..:....:..|.:|.:..:........:::.   .....|.::.
  Fly   826 LTTSPVKNHAS--SPLAQQLLEAASSAKNDAQILEKMKSLLSRYAAGNQTKAGVGATATAANKIN 888

  Fly 11051 LQITKTTVYDEYPDLPVHIT---EQNKVLI--ASQQSKRS-------------GAGPTSSAVTIE 11097
            ....||.||:::....||..   |:::...  |..:||||             ||| :.:|....
  Fly   889 SNGKKTPVYEDFTTAWVHSNGNLERSESCSPPAKARSKRSSAASSCESNNSNAGAG-SGAAAGSA 952

  Fly 11098 EVGSPTEELVVPITPGP 11114
            .|.||..|..:...|.|
  Fly   953 SVVSPRRERGMSKIPAP 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Msp300	NP_001188695.1	SPEC	17..220	CDD:238103
		EnvC	194..>393	CDD:443969
		PTZ00121	<1704..1881	CDD:173412
		SPEC	9546..9732	CDD:413338
		rne	<10668..10827	CDD:236766	25/165 (15%)
		SMC_prok_B	11268..12195	CDD:274008
		YhaN	11930..12426	CDD:443752
		SMC_prok_B	<12205..12954	CDD:274008
		YhaN	12817..>13241	CDD:443752
		SPEC	13196..13374	CDD:238103
		KASH	13484..13540	CDD:463142
pigs	NP_572331.2	CH_GAS2L1_2	11..163	CDD:409117	8/46 (17%)
		GAS2	257..325	CDD:460480	15/79 (19%)