DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Msp300 and GAS2

DIOPT Version :9

Sequence 1:	NP_001188695.1	Gene:	Msp300 / 3771968	FlyBaseID:	FBgn0261836	Length:	13540	Species:	Drosophila melanogaster
Sequence 2:	NP_001378862.1	Gene:	GAS2 / 2620	HGNCID:	4167	Length:	331	Species:	Homo sapiens

Alignment Length:	170	Identity:	36/170 - (21%)
Similarity:	56/170 - (32%)	Gaps:	57/170 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  3886 EWIDNTVTHIKTAVTPLPDVKEPIKKDKKPQKPKKQKATKK-PTPVALPEDEVSSEPSEEIVVEC 3949
            |.:||.....:.|.|    ::|..|:.....||.|....|| |...:.|.....:.
Human    59 EKLDNGALLCQLAET----MQEKFKESMDANKPTKNLPLKKIPCKTSAPSGSFFAR--------- 110

  Fly  3950 EVEEKETKSIKNTENAFSWASLVKKPGEWVDDIASRKKPVEIIHEEPKE---------------- 3998
                      .||.|..||.   :..|  ||:....:....::|::|:|
Human   111 ----------DNTANFLSWC---RDLG--VDETCLFESEGLVLHKQPREVCLCLLELGRIAARYG 160

  Fly  3999 VHP----------RKERKISKPQPKPQSENTTKRNNKKET 4028
            |.|          .:|..:|.|.|.|..  ::|.:.||.|
Human   161 VEPPGLIKLEKEIEQEETLSAPSPSPSP--SSKSSGKKST 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Msp300	NP_001188695.1	SPEC	17..220	CDD:238103
		SPEC	9546..9732	CDD:295325
		sbcc	11187..12008	CDD:129705
		SMC_prok_B	11614..12442	CDD:274008
		SPEC	11994..12156	CDD:295325
		SPEC	12374..12564	CDD:295325
		Lipase_chap	12376..12529	CDD:281297
		SPEC	12703..12923	CDD:238103
		SPEC	12816..13032	CDD:295325
		SPEC	13196..13374	CDD:238103
		KASH	13484..13540	CDD:287506
GAS2	NP_001378862.1	CH_GAS2	29..163	CDD:409116	26/131 (20%)
GAS2	NP_001378862.1	GAS2	200..291	CDD:413356
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900