| Sequence 1: | NP_001188695.1 | Gene: | Msp300 / 3771968 | FlyBaseID: | FBgn0261836 | Length: | 13540 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001307676.1 | Gene: | EVPL / 2125 | HGNCID: | 3503 | Length: | 2055 | Species: | Homo sapiens |
| Alignment Length: | 2023 | Identity: | 400/2023 - (19%) |
|---|---|---|---|
| Similarity: | 733/2023 - (36%) | Gaps: | 645/2023 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 11383 AAQQQLAHLCQ----NARAFQRDFPGKKMPQDVHNAFETSKNI-ANNIQAERERVLQLQSLAEEY 11442
Fly 11443 EQTLKEFTKITVLADKLVESPIVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETREK 11507
Fly 11508 HSELHKELYNRATSLLDKASERSSKLVQAASRWTVLEKGMRDELQWLQVAQQRVPDLSAVTSADY 11572
Fly 11573 DQYTTLYQSLSNDISHHYVKMTQLSGIANKLQLLV--QAPNLVEETNEALIVLLKL-----REEV 11630
Fly 11631 ALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQELRNIQIPSQPTHQPIEHMRQFWEIKARFELH 11695
Fly 11696 NNVRTDTGLSFEKSLQVIPLADEMLQRQFHAQLEDRWQAVAQAIELIQHNIVECLSSEDVPADEK 11760
Fly 11761 LKMVERELQEIYLTMTSMKGVIKNEEELCLYIERVQVLRTRVGFIGNELGRIGLQEPAIEPEKVG 11825
Fly 11826 ELFSLSHKISTQIAEELEGASVLRDQLQAIQEGISNQRKH-QAKIS-----------VILDECEA 11878
Fly 11879 AERQGADVLEKAVADCQAAGEELVISWQEIMRIRQMLHTLPMRLKMSVSPVKLER-------DIS 11936
Fly 11937 QLQ----------DDHAFL------ESK-----CTNIM-----AILR-SRLAVWLRYERQ----- 11969
Fly 11970 --------LELVHGSVQETD--------------FMMELIRVHGQVDYERLRKATERLEGLAGDL 12012
Fly 12013 HNREQLIDELKGAAKPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYR 12077
Fly 12078 N----ASAAVK-----NSIDQQMDAVKSL-----EQPLDALQHAKVCQDNLTTQNDRILELRDIV 12128
Fly 12129 AKIAADVGLDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQ 12193
Fly 12194 QDISREAPQNPKESEEQLAALRAHL----QTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILE 12254
Fly 12255 VLALWQKIFQD---TFQEYHRLSTRLA-------RSQ--------NSSEALRLWRQYLQHVQ--- 12298
Fly 12299 ------SFLSCAIP---EDYSSLREQQQLCAIHQNLLISQQSVLSETPLESELSEQYKALTNLHN 12354
Fly 12355 ETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQ----------------------------R 12391
Fly 12392 EAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELAR-HCDDALATAMRMEQ 12455
Fly 12456 ASI---GQRISNLRAALKTWQGFLQRVTQLSESYE--------QRVNQLQQEFGAAQKLLDANSE 12509
Fly 12510 SLPTQPAAIEQLLGS---LRAQRVQLGAQVSALESLTVTQEE---LKECIS-PHDMKTIRQRNWL 12567
Fly 12568 LWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTAMTNPE---QA 12629
Fly 12630 AKQLEQ-----QVNSELQ-LRDKEREWLLSTSRELLTLYSE--------PEVR--------SQVQ 12672
Fly 12673 QQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLDKP-LNFESYTPN 12736
Fly 12737 VIEAKLKEHE---QIQRSIEHHSSNVGEVLN--------LVEMLLNDADSW---RTQVNTSG--- 12784
Fly 12785 ----------LAASAQNLEQRWKNVCSQSAERKARILTIWNL-----------------LQQLIK 12822
Fly 12823 LTAEHKNWLGKQESQIAGFERDQKSHSKHKLEERQMELRAKLEE-------LESQSVNL---RQL 12877
Fly 12878 EQIYAKLAMSAGVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKD----AKLMREFNNAQL 12938
Fly 12939 EATNSLNAIQKALEQLPSAENQQTSKAEPKAVLQRLESLEKK--LQDAQQHVQQADNLAQEAKTR 13001
Fly 13002 TKQQPQLKQLLELVSAYTTLWQTVQTRIVTLKTTW------LTRAAQAAASLPVSEAANAAVQVN 13060
Fly 13061 TLSQRKLRQAQQMQRETSITA------------KDAYIMELQTAITECQNNLDELQRTVVDKTRK 13113
Fly 13114 PGPQKIAK 13121 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Msp300 | NP_001188695.1 | SPEC | 17..220 | CDD:238103 | |
| SPEC | 9546..9732 | CDD:295325 | |||
| sbcc | 11187..12008 | CDD:129705 | 134/709 (19%) | ||
| SMC_prok_B | 11614..12442 | CDD:274008 | 184/982 (19%) | ||
| SPEC | 11994..12156 | CDD:295325 | 35/175 (20%) | ||
| SPEC | 12374..12564 | CDD:295325 | 54/236 (23%) | ||
| Lipase_chap | 12376..12529 | CDD:281297 | 46/195 (24%) | ||
| SPEC | 12703..12923 | CDD:238103 | 53/274 (19%) | ||
| SPEC | 12816..13032 | CDD:295325 | 47/248 (19%) | ||
| SPEC | 13196..13374 | CDD:238103 | |||
| KASH | 13484..13540 | CDD:287506 | |||
| EVPL | NP_001307676.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..37 | 2/2 (100%) | |
| 4 X 4 AA tandem repeats of K-G-S-P | 12..28 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 65..85 | 5/22 (23%) | |||
| SPEC | 228..415 | CDD:238103 | 52/307 (17%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 388..418 | 8/43 (19%) | |||
| Central fibrous rod domain | 864..1695 | 189/940 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 913..938 | 2/24 (8%) | |||
| Smc | 934..1698 | CDD:224117 | 177/854 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1636..1658 | 2/21 (10%) | |||
| Globular 2 | 1696..2055 | 400/2023 (20%) | |||
| Plectin | <1710..1740 | CDD:279071 | |||
| PLEC | 1840..1877 | CDD:197605 | |||
| Plectin | 1879..1920 | CDD:279071 | |||
| PLEC | 1916..1953 | CDD:197605 | |||
| Plectin | 1957..1996 | CDD:279071 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0516 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||