DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Msp300 and Gas2

DIOPT Version :9

Sequence 1:	NP_001188695.1	Gene:	Msp300 / 3771968	FlyBaseID:	FBgn0261836	Length:	13540	Species:	Drosophila melanogaster
Sequence 2:	XP_006540681.1	Gene:	Gas2 / 14453	MGIID:	95657	Length:	341	Species:	Mus musculus

Alignment Length:	333	Identity:	67/333 - (20%)
Similarity:	103/333 - (30%)	Gaps:	117/333 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  3886 EWIDNTVTHIKTAVTPLPDVKEPIKKDK--KPQKPK-------KQKATKKPTPVALPEDEVSSE- 3940
            |.:||.....:.|.|.....||.:..:|  ||..|.       ..|.|:.||      ..:||:
Mouse    60 EKLDNGALLCQLAATVQEKFKESMDANKPAKPHSPHFEAGFYLTSKMTQNPT------SSLSSKT 118

  Fly  3941 -PSEEIVVECEVEEKETKSIKNTENAFSWASLVKKPGEWVDDIASRKKPVEIIHEEPKE------ 3998
             |.::|..:.........:..||.|..||.   :..|  ||:....:....::|::|:|
Mouse   119 LPLKKIPCKASAPSGSFFARDNTANFLSWC---RDLG--VDETCLFESEGLVLHKQPREVCLCLL 178

  Fly  3999 ----------VHP----------RKERKISKPQPKPQSENTTKRNNKKETREPV--VVHSTSEES 4041
                      |.|          .:|..:|.|.|.|..  ::|.:.||.|...:  .|...||:
Mouse   179 ELGRIAARYGVEPPGLIKLEKEIEQEETLSAPSPSPSP--SSKSSGKKSTGNLLDDAVKRISED- 240

  Fly  4042 DVVEVLEPTNENTITWAKIASQIDHMTDLKPKAKQETK-----PKQGE-RVKEQIRFDRI--EKH 4098
                                          |..|..||     ..||. ||.|:|.|.|:  .||
Mouse   241 ------------------------------PPCKCPTKFCVERLSQGRYRVGEKILFIRMLHNKH 275

  Fly  4099 PKDHAISSDLSQQKGDSGHSWSSVVSHQVTDFIEAESIKPVPKKSVKKSSGNTQPKIAPKLEEPL 4163
            .....            |..|.:...:.:..       .|.....:.:..|.|.|..:
Mouse   276 VMVRV------------GGGWETFAGYLLKH-------DPCRMLQISRVDGKTSPVQS------- 314

  Fly  4164 QEPVQKDV 4171
            :.|..||:
Mouse   315 KSPTLKDM 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Msp300	NP_001188695.1	SPEC	17..220	CDD:238103
		SPEC	9546..9732	CDD:295325
		sbcc	11187..12008	CDD:129705
		SMC_prok_B	11614..12442	CDD:274008
		SPEC	11994..12156	CDD:295325
		SPEC	12374..12564	CDD:295325
		Lipase_chap	12376..12529	CDD:281297
		SPEC	12703..12923	CDD:238103
		SPEC	12816..13032	CDD:295325
		SPEC	13196..13374	CDD:238103
		KASH	13484..13540	CDD:287506
Gas2	XP_006540681.1	CH_SF	30..191	CDD:412120	31/141 (22%)
Gas2	XP_006540681.1	GAS2	228..301	CDD:128539	20/122 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900