Protein Alignment HemK2 and Hemk1

DIOPT Version :9

• Sequence 1: NP_001027221.1
• Gene: HemK2 / 3771966
• FlyBaseID: FBgn0031454
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_598745.2
• Gene: Hemk1 / 69536
• MGIID: 1916786
• Length: 340
• Species: Mus musculus
• Alignment Length: 182
• Identity: 45/182 - (24%)
• Similarity: 75/182 - (41%)
• Gaps: 31/182 - (17%)

  Fly    45 LCVELGSGSGVIITALAKKLAGFSLCLATDINPKACNATRRTATRNGARLDSIRCSLADA----- 104
            |.:|:|.|||.|..:|..:|.. |..:|.|....|.:.|...|.|...: |.||....|.
Mouse   163 LILEVGCGSGAITLSLLSQLPK-SRVVAVDKEEAAVSLTHENAQRLQLQ-DRIRIIHLDITSEGC 225

  Fly   105 ---LRPRS-VDVLLFNPPYVVTSDEELQTQQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQL 165
               |.|.| :|:::.||||:...|.|....:..|:.:       :.:..||.:|..:...:|...
Mouse   226 CTHLLPWSPLDLVVSNPPYIFRKDMEQLAPEICSYED-------LVALDGGDEGMDIITHILTLA 283

  Fly   166 DDILSPRGVLYLLLLRENKPEEIIKYLEGLQFRAVKFMERRIPGEHLCILKV 217
            ..:|:..|.:: |.:....||.:..:|:.            .|..||.::.|
Mouse   284 PQLLNASGSIF-LEVDPRHPELVSSWLQS------------HPDLHLSLVGV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HemK2	NP_001027221.1	AdoMet_MTases	15..219	CDD:302624	45/182 (25%)
		HemK	<15..193	CDD:225443	40/156 (26%)
Hemk1	NP_598745.2	RF_mod_PrmC	64..333	CDD:274634	45/182 (25%)
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250	168..172		2/3 (67%)
		Substrate binding. /evidence=ECO:0000250	241..244		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2890
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R762
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840