Protein Alignment HemK2 and N6amt1

DIOPT Version :9

• Sequence 1: NP_001027221.1
• Gene: HemK2 / 3771966
• FlyBaseID: FBgn0031454
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_080642.1
• Gene: N6amt1 / 67768
• MGIID: 1915018
• Length: 214
• Species: Mus musculus
• Alignment Length: 220
• Identity: 84/220 - (38%)
• Similarity: 122/220 - (55%)
• Gaps: 17/220 - (7%)

  Fly     3 TPYTDHLSPEDFEHVYEPAEDSFLLLDALEKDLEYLDRLQPSLCVELGSGSGVIITALAKKLAGF 67
            ||...|:....|..|||||||:||||||||.....|..::  :|:|:|:||||:...||..:...
Mouse     8 TPLYGHVGRGAFRDVYEPAEDTFLLLDALEAAAAELAGVE--ICLEVGAGSGVVSAFLASMIGPR 70

  Fly    68 SLCLATDINPKACNATRRTATRNGARLDSIRCSLADALRPR---SVDVLLFNPPYVVTSDEELQT 129
            :|.:.|||||:|...|..||..|...:..:...|...|.||   .||:|:||||||||..||:.:
Mouse    71 ALYMCTDINPEAAACTLETARCNRVHVQPVITDLVHGLLPRLKGKVDLLVFNPPYVVTPPEEVGS 135

  Fly   130 QQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQLDDILSPRGVLYLLLLRENKPEEIIKYLEG 194
                        |.:..:||||::||.|.|.......::|||||:.||:.::||.||||.|.::.
Mouse   136 ------------RGIEAAWAGGRNGREVMDRFFPLAPELLSPRGLFYLVTVKENNPEEIFKTMKT 188

  Fly   195 LQFRAVKFMERRIPGEHLCILKVTR 219
            ...:....:.|:...|.|.:|:.::
Mouse   189 RGLQGTTALCRQAGQEALSVLRFSK 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HemK2	NP_001027221.1	AdoMet_MTases	15..219	CDD:302624	80/206 (39%)
		HemK	<15..193	CDD:225443	76/180 (42%)
N6amt1	NP_080642.1	AdoMet_MTases	21..213	CDD:327401	80/205 (39%)
		S-adenosyl-L-methionine binding. /evidence=ECO:0000250|UniProtKB:P0ACC1, ECO:0000255|HAMAP-Rule:MF_02126	53..57		2/3 (67%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:P0ACC1	122..125		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836943
Domainoid	1	1.000	70	1.000	Domainoid score	I9563
eggNOG	1	0.900	-	-		E1_COG2890
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5637
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4465
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54278
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004328
OrthoInspector	1	1.000	-	-		oto94627
orthoMCL	1	0.900	-	-		OOG6_101563
Panther	1	1.100	-	-	LDO	PTHR45875
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R762
SonicParanoid	1	1.000	-	-		X3597
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790