Protein Alignment HemK2 and HEMK1

DIOPT Version :9

• Sequence 1: NP_001027221.1
• Gene: HemK2 / 3771966
• FlyBaseID: FBgn0031454
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_011532108.1
• Gene: HEMK1 / 51409
• HGNCID: 24923
• Length: 355
• Species: Homo sapiens
• Alignment Length: 158
• Identity: 42/158 - (26%)
• Similarity: 68/158 - (43%)
• Gaps: 20/158 - (12%)

  Fly    45 LCVELGSGSGVIITALAKKLAGFSLCLATDINPKACNATRRTATRNGARL-DSIRCSLADALRPR 108
            |.:|:|.|||.|..:|..:|.. |..:|.|....|.:.|...|.|  .|| |.|.....|....|
Human   162 LILEVGCGSGAISLSLLSQLPQ-SRVIAVDKREAAISLTHENAQR--LRLQDRIWIIHLDMTSER 223

  Fly   109 S--------VDVLLFNPPYVVTSDEELQTQQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQL 165
            |        :|:::.|||||...|.|....:..|:.:.:       :..||::|..:...:|...
Human   224 SWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPA-------ALDGGEEGMDIITHILALA 281

  Fly   166 DDILSPRGVLYLLLLRENKPEEIIKYLE 193
            ..:|...|.:: |.:....||.:..:|:
Human   282 PRLLKDSGSIF-LEVDPRHPELVSSWLQ 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HemK2	NP_001027221.1	AdoMet_MTases	15..219	CDD:302624	42/158 (27%)
		HemK	<15..193	CDD:225443	41/156 (26%)
HEMK1	XP_011532108.1	RF_mod_PrmC	63..326	CDD:274634	42/158 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2890
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R762
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840