Protein Alignment HemK2 and HemK1

DIOPT Version :9

• Sequence 1: NP_001027221.1
• Gene: HemK2 / 3771966
• FlyBaseID: FBgn0031454
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001260134.1
• Gene: HemK1 / 33902
• FlyBaseID: FBgn0031817
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 221
• Identity: 60/221 - (27%)
• Similarity: 95/221 - (42%)
• Gaps: 47/221 - (21%)

  Fly    10 SPEDFEHVYEPAEDSF--LLLDALEKDLEYLDRLQPSLCVELGSGSG------------VIITAL 60
            ||..|  :..|..:.|  |::|. .|:.:::|.|      |:|.|||            |:.||:
  Fly   120 SPSVF--IPRPETEEFMRLVIDD-HKNAKHVDLL------EVGCGSGAMSLSMLHSLPQVVATAI 175

  Fly    61 AKKLAGFSLCLATDINPKACNATRRTATRNGARLDSIRCSLADALRPRSVDVLLFNPPYVVTSDE 125
            .:..|  :..||.: |.|......|....|....:.  ..|.:||:.:..|:::.|||||.|  |
  Fly   176 ERSKA--ATVLAAE-NAKMLGLLNRFEVHNHTMEED--KYLPEALKDKKYDLIISNPPYVKT--E 233

  Fly   126 ELQTQQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQLDDILSPRGVLYLLLLRENKP----- 185
            |.|.    .|.|.....|| .:..||.||.||..::.......|.|.|.|:|.|..::.|
  Fly   234 EFQF----LHPEVVVYENL-NALDGGSDGLRVARLVFDLACRHLRPGGKLWLELGNDHPPMVKTI 293

  Fly   186 -----EEIIKYLEGL--QFRAVKFME 204
                 |..:|::.|.  |::..:|::
  Fly   294 MNLKYEGRLKFIAGYSDQYQRERFVQ 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HemK2	NP_001027221.1	AdoMet_MTases	15..219	CDD:302624	57/216 (26%)
		HemK	<15..193	CDD:225443	54/201 (27%)
HemK1	NP_001260134.1	PRK09328	61..322	CDD:236467	60/221 (27%)
		AdoMet_MTases	84..288	CDD:302624	54/188 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467929
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2890
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R762
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.770