DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment waw and mEFTu1

DIOPT Version :9

Sequence 1:	NP_001027089.1	Gene:	waw / 3771960	FlyBaseID:	FBgn0024182	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	NP_001163144.1	Gene:	mEFTu1 / 44438	FlyBaseID:	FBgn0024556	Length:	489	Species:	Drosophila melanogaster

Alignment Length:	472	Identity:	113/472 - (23%)
Similarity:	181/472 - (38%)	Gaps:	121/472 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 LREFAH--MPVERIR---NFSIIAHVDHGKSTLADRLLELTGAIAR--------NGGQHQVLDNL 139
            |||:|:  ...||.:   |...|.||||||:|       ||.||.:        ...::..:||.
  Fly    66 LREYANEKKVFERTKPHCNVGTIGHVDHGKTT-------LTAAITKVLADKQLAESKKYNEIDNA 123

  Fly   140 QVERERGIT-----VKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDAC 199
            ..|:.||||     |:.||.:   ||.|.      .|.|||.|:...:....|..||.:|:|.|.
  Fly   124 PEEKARGITINVAHVEYQTET---RHYGH------TDCPGHADYIKNMITGTAQMDGAILVVAAT 179

  Fly   200 HGVQAQTVANYHLAKQRQL-AVVPVLNKIDIKHANPDQV------CQDLKLLFGIDPDEVLRV-- 255
            .|...||..:..||||..: .:|..:||:|.  |:.:.|      .::|....|.|.|::..|
  Fly   180 DGAMPQTREHMLLAKQIGIDHIVVFINKVDA--ADEEMVDLVEMEIRELLTEMGYDGDKIPVVKG 242

  Fly   256 ---------SAKLG-TGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGK 310
                     |.::| ..:.::|:.|...:|.|..:.|..|...:.:.:....||.     |:.|:
  Fly   243 SALCALEDKSPEIGKEAILKLLQEVDSFIPTPVRELDKPFLLPVENVYSIPGRGT-----VVTGR 302

  Fly   311 LEQNQDIQSLATKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQAV 375
            ||:.                 .|.:..||.          .:..| :..|.::.|  :.:.:|.:
  Fly   303 LERG-----------------VVKKGMECE----------FVGYN-KVLKSTVTG--VEMFHQIL 337

  Fly   376 --AAAGSYRPQQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRL-GFLG 437
              |.||.   |...:..||...|..:.:.:........|:.....|.|.|.   .:|.|. .|:.
  Fly   338 EEAQAGD---QLGALVRGVKRDDIKRGMVMCKPGSVKALDQLEAQVYILSK---DEGGRTKPFMS 396

  Fly   438 LLHMEVF-----CQRLEQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMDISNAALFPEPHSI 497
            .:.:::|     |....|....|.::........|.|..|.:::|..|.|:...|
  Fly   397 FIQLQMFSRTWDCAVQVQIPDKEMVMPGEDTKLILRLIRPMVLEQGQRFTLRDGN---------- 451

  Fly   498 KEYYEPLVLGT-IITPT 513
                  |.||| ::|.|
  Fly   452 ------LTLGTGVVTST 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
waw	NP_001027089.1	PRK05433	94..695	CDD:235462	109/464 (23%)
		LepA	100..277	CDD:206677	60/211 (28%)
		EF4_II	285..370	CDD:293900	13/84 (15%)
		EF4_III	386..461	CDD:293917	14/80 (18%)
		lepA_C	502..581	CDD:239680	6/13 (46%)
		LepA_C	589..695	CDD:283959
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	109/465 (23%)
		EF_Tu	81..274	CDD:206671	60/210 (29%)
		EFTU_II	282..368	CDD:293898	21/123 (17%)
		mtEFTU_III	371..462	CDD:294005	23/109 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464555
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840