Protein Alignment waw and Guf1

DIOPT Version :10

• Sequence 1: NP_001027089.1
• Gene: waw / 3771960
• FlyBaseID: FBgn0024182
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001100685.1
• Gene: Guf1 / 305317
• RGDID: 1310774
• Length: 659
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 345/615 - (56%)
• Similarity: 456/615 - (74%)
• Gaps: 2/615 - (0%)

  Fly    83 SQADLLR--EFAHMPVERIRNFSIIAHVDHGKSTLADRLLELTGAIARNGGQHQVLDNLQVERER 145
            |.|:|..  :.:..|||.||||||||||||||||||||||||||.|.:.....||||.|||||||
  Rat    40 SAAELKEKPDMSRFPVEDIRNFSIIAHVDHGKSTLADRLLELTGTIDKTQKNKQVLDKLQVERER 104

  Fly   146 GITVKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDGVVLLVDACHGVQAQTVANY 210
            ||||||||||:|:...|:.|||||||||||||||.||||||:||.||:|:|||..|:|||||||:
  Rat   105 GITVKAQTASLFYSFGGKQYLLNLIDTPGHVDFSYEVSRSLSACQGVLLVVDANEGIQAQTVANF 169

  Fly   211 HLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDPDEVLRVSAKLGTGVSEVLERVIETVP 275
            .||.:.||:|:||:||||:|:|:|::|.:.::.:|.|..:|.:::||||||.|..||:.|||.:|
  Rat   170 FLAFEAQLSVIPVINKIDLKNADPERVGKQIEKVFDIPSEECIKISAKLGTNVDSVLQAVIERIP 234

  Fly   276 PPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDIQSLATKKVYSVKSISVLRPAECP 340
            ||:|.|.:..:||:|||.||:|||.:..|.:.:|.|.:...|.|..|||.|.|..:.:|.|.|.|
  Rat   235 PPKVHRANPLKALVFDSTFDQYRGVVASIALFDGMLSKGDKIVSAHTKKTYEVNQVGILNPNEQP 299

  Fly   341 VPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQAVAAAGSYRPQQPLVFAGVFPADQSKHVALRS 405
            ...:.|||||.:...|::..|:.:|||::|.|..|.....::..:|:|||||:|.|||::..|:|
  Rat   300 THKLYAGQVGFLIAGMKDVTEAQIGDTLYLHNHPVEPLPGFKSAKPMVFAGVYPIDQSEYNNLKS 364

  Fly   406 AIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVFCQRLEQEHGAEPIITAPSVTYRLVLS 470
            ||:|:.||||:|||..|||.|||.|||||||||||||||.||||||:.|..|:|.|:|.|:.|||
  Rat   365 AIEKLTLNDSSVTVHRDSSLALGAGWRLGFLGLLHMEVFNQRLEQEYNASVILTTPTVPYKAVLS 429

  Fly   471 NPKMIKQQGRDTMDISNAALFPEPHSIKEYYEPLVLGTIITPTEYVGQVISLCVERRGLQQSSVN 535
            :.|:||:.....:.|.|.|.||:...:.||.||:||||:||||||.|:::.||..||.:|::...
  Rat   430 SAKLIKEYKEKEITIINPAQFPDKSKVTEYLEPVVLGTVITPTEYTGKIMELCQARRAIQKNMTF 494

  Fly   536 IDDTRVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYEDHGYHPSHLVRLDIHLNGKPVEELCRI 600
            ||:.||::||:.||:||::||:|.|||||||||||.|||.||..:.|:::||.|||..||||..:
  Rat   495 IDENRVMLKYLFPLNEIVVDFYDSLKSLSSGYASFDYEDAGYQTADLIKMDILLNGNIVEELVTV 559

  Fly   601 VHVSKATGVARQMVLKLRELIPKQMVQIAIQACVGSKVLARETIKAYRKDVTAKLYGGDVTRRMK 665
            ||..||..|.:.:..:|::.:|:|:.:||:||.:||||:||||:|||||:|.||.||||:||:||
  Rat   560 VHREKAYTVGKSICERLKDSLPRQLFEIAVQAAIGSKVIARETVKAYRKNVLAKCYGGDITRKMK 624

  Fly   666 LLKQQAEGKKKMRMFANIRVPHETFINVLK 695
            |||:|||||||:|...||.:|...||.|||
  Rat   625 LLKRQAEGKKKLRKIGNIEIPKNAFIKVLK 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
waw	NP_001027089.1	LepA	94..695	CDD:440249	340/600 (57%)
Guf1	NP_001100685.1	LepA	49..655	CDD:440249	342/606 (56%)