Protein Alignment waw and SPAC1B3.04c

DIOPT Version :9

• Sequence 1: NP_001027089.1
• Gene: waw / 3771960
• FlyBaseID: FBgn0024182
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_594788.2
• Gene: SPAC1B3.04c / 2542529
• PomBaseID: SPAC1B3.04c
• Length: 652
• Species: Schizosaccharomyces pombe
• Alignment Length: 643
• Identity: 277/643 - (43%)
• Similarity: 415/643 - (64%)
• Gaps: 17/643 - (2%)

  Fly    60 RSKSLLVR----NLS-TTNQVKGETEEPSQADLLREFAHMPVERIRNFSIIAHVDHGKSTLADRL 119
            :|.|..:|    ::| .:.::..|..:||..:::|   .:|..|:||:::|||:|||||||:|.:
pombe    17 KSSSFKIRWRFFSVSYASRKLASEDNKPSIQEVVR---GIPQNRVRNWAVIAHIDHGKSTLSDCI 78

  Fly   120 LELTGAIARNGGQHQVLDNLQVERERGITVKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSR 184
            |:|||.|..:..::|.||.|:|||.|||||||||.|:.:.:.||.||||||||||||||..||..
pombe    79 LKLTGVINEHNFRNQFLDKLEVERRRGITVKAQTCSMIYYYHGQSYLLNLIDTPGHVDFRAEVMH 143

  Fly   185 SLAACDGVVLLVDACHGVQAQTVANYHLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDP 249
            |||||:|.:|||||..|:||||::|:::|..:.|.::|||||:|:..|:.|:....::..|.|..
pombe   144 SLAACEGCILLVDASQGIQAQTLSNFYMAFSQNLVIIPVLNKVDLPTADVDRTLIQVQQTFDIPM 208

  Fly   250 DEVLRVSAKLGTGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQN 314
            .:.:.||:|.|..|.::|..:|:.:|||:...::..|.|:.|||::.|:|.:.|:.::.|.:::.
pombe   209 SKPILVSSKTGKNVEQILPEIIQKIPPPKGSENAPLRCLLIDSWYNSYQGVIGLVRIMEGFIKKG 273

  Fly   315 QDIQSLATKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLKNQAVAAAG 379
            ..:.|:.|.:.|.|:.:.::.|....|..:.|||||.|..||:|..|:|||||.......|.|..
pombe   274 GKVMSVNTGRKYEVQQVGIMYPDMTEVSRLRAGQVGYIIWNMKNIDEAIVGDTYSTIGSNVEALP 338

  Fly   380 SYRPQQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVF 444
            .:...|.:|:.|.||.|.|.:..|...|:::.|||.|:.|:.::|.|||.||||||||.||:.||
pombe   339 GFSIPQSMVYVGAFPLDGSDYERLNDNIEQLALNDRAINVQKENSSALGMGWRLGFLGTLHLSVF 403

  Fly   445 CQRLEQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMDISNAALFPEPH-SIKEYYEPLVLGT 508
            ..||:.|:|.|.:||:|:|.||:...|       ||:.: |||..|||..| .|.|..||.|..|
pombe   404 IDRLKDEYGKELLITSPTVPYRIKYKN-------GREEV-ISNPNLFPTNHQGISELLEPTVDAT 460

  Fly   509 IITPTEYVGQVISLCVERRGLQQSSVNIDDTRVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYE 573
            ||||:||:|.||.||...||||:....:.::|.::||.|||:.::.||..|||..:||:|:..||
pombe   461 IITPSEYLGDVIKLCESCRGLQKDCTYMSESRCMIKYQLPLAHLVEDFFGRLKGTTSGFATLDYE 525

  Fly   574 DHGYHPSHLVRLDIHLNGKPVEELCRIVHVSKATGVARQMVLKLRELIPKQMVQIAIQACVGSKV 638
            :..|.|:.||||.|.::||.|:.||.|||.|.|....|:.:.:|:.|:|||:.::.:||.:.::|
pombe   526 ESDYVPADLVRLSIFMSGKSVDALCSIVHRSLALQRGREWIQRLKPLVPKQLYEVILQAVIDNRV 590

  Fly   639 LARETIKAYRKDVTAKLYGGDVTRRMKLLKQQAEGKKKMRMFANIRVPHETFINVLKR 696
            :|||:|.|.||:||||.|||||||:.|||.:|.||||:::...|:.:....|...|.:
pombe   591 VARESISALRKNVTAKCYGGDVTRKQKLLNKQKEGKKRLKSVGNVSIDKSVFYEFLTK 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
waw	NP_001027089.1	PRK05433	94..695	CDD:235462	268/601 (45%)
		LepA	100..277	CDD:206677	90/176 (51%)
		EF4_II	285..370	CDD:293900	30/84 (36%)
		EF4_III	386..461	CDD:293917	36/74 (49%)
		lepA_C	502..581	CDD:239680	37/78 (47%)
		LepA_C	589..695	CDD:283959	47/105 (45%)
SPAC1B3.04c	NP_594788.2	LepA	50..646	CDD:223557	269/606 (44%)
		LepA	59..236	CDD:206677	90/176 (51%)
		EF4_II	244..326	CDD:293900	28/81 (35%)
		EF4_III	345..420	CDD:293917	36/74 (49%)
		lepA_C	454..533	CDD:239680	37/78 (47%)
		LepA_C	543..646	CDD:283959	47/102 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	192	1.000	Domainoid score	I714
eggNOG	1	0.900	-	-		E1_COG0481
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6505
Inparanoid	1	1.050	535	1.000	Inparanoid score	I209
OMA	1	1.010	-	-		QHG53758
OrthoFinder	1	1.000	-	-		FOG0003399
OrthoInspector	1	1.000	-	-		oto100699
orthoMCL	1	0.900	-	-		OOG6_100972
Panther	1	1.100	-	-	LDO	PTHR43512
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R536
SonicParanoid	1	1.000	-	-		X2295
TreeFam	1	0.960	-	-
	14	13.860