Protein Alignment waw and ZK1236.1

DIOPT Version :10

• Sequence 1: NP_001027089.1
• Gene: waw / 3771960
• FlyBaseID: FBgn0024182
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_498863.1
• Gene: ZK1236.1 / 176191
• WormBaseID: WBGene00022862
• Length: 645
• Species: Caenorhabditis elegans
• Alignment Length: 647
• Identity: 291/647 - (44%)
• Similarity: 419/647 - (64%)
• Gaps: 21/647 - (3%)

  Fly    62 KSLLVRNLSTTNQVKGETEEPSQADLLREFAHMPVERIRNFSIIAHVDHGKSTLADRLLELTGAI 126
            |.|.:..|..:.:......:|::...|.||.   .::||||.|:||||||||||||||||:.||:
 Worm     8 KLLFIGKLRVSCKHYSTAGDPTKLVNLSEFT---PDKIRNFGIVAHVDHGKSTLADRLLEMCGAV 69

  Fly   127 ARNGGQHQVLDNLQVERERGITVKAQTASIFHRHKGQLYLLNLIDTPGHVDFSNEVSRSLAACDG 191
            .  .||.|:||.||||||||||||||||::  ||:|  |||||||||||||||.|||||||.|||
 Worm    70 P--PGQKQMLDKLQVERERGITVKAQTAAL--RHRG--YLLNLIDTPGHVDFSAEVSRSLAVCDG 128

  Fly   192 VVLLVDACHGVQAQTVANYHLAKQRQLAVVPVLNKIDIKHANPDQVCQDLKLLFGIDPDEVLRVS 256
            ::|||.|..||||||:||:.||.::.:.::||:||||:..|:...|...||.||..:|:|.|.:|
 Worm   129 ILLLVAANQGVQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNLFEFNPEECLHIS 193

  Fly   257 AKLGTGVSEVLERVIETVPPPQVQRDSDFRALIFDSWFDKYRGALNLIYVLNGKLEQNQDIQSLA 321
            ||.|..|.:|||.:|:.||.|....|:.||::||||:||.:|||:..|.|..|.:::...|||..
 Worm   194 AKSGLNVDKVLEAIIDRVPAPTAIIDAPFRSMIFDSYFDHFRGAIAHIMVKEGSVKKGDKIQSYQ 258

  Fly   322 TKKVYSVKSISVLRPAECPVPDVSAGQVGLIACNMRNSKESIVGDTIHLK---NQAVAAAGSYRP 383
            .:|||.|..:.|:||......::.|||||.:.||||...|::||:|:..:   ..:|......:.
 Worm   259 NEKVYDVSEVGVMRPEMVKCTELRAGQVGYLVCNMRTVNEAVVGETLFAETTSRDSVKTFAEIKG 323

  Fly   384 QQPLVFAGVFPADQSKHVALRSAIDKMVLNDSAVTVKIDSSPALGQGWRLGFLGLLHMEVFCQRL 448
            .:|.|:||:||.:.|.:.:|:.|::::.|||.:|||..|||.|||.|||:||||:||||||..||
 Worm   324 VKPTVYAGLFPVETSDYESLKQAVERLCLNDPSVTVIPDSSKALGLGWRIGFLGVLHMEVFGARL 388

  Fly   449 EQEHGAEPIITAPSVTYRLVLSNPKMIKQQGRDTMD---ISNAALFPEPHSIKEYYEPLVLGTII 510
            .||:.|..|:..|||.||..:.:.:.|:::..|.|:   |.:.:.||:...:..:.||:|...:|
 Worm   389 SQEYDASVILCQPSVEYRAKIKDNETIRKKRYDGMEEIRILDPSKFPDESDVDSFLEPMVKVRMI 453

  Fly   511 TPTEYVGQVISLCVERRGLQQSSVNIDDTRVLMKYVLPLSEIILDFHDRLKSLSSGYASFSYEDH 575
            .|.|.:|.|..||.|.||.:....:||.||:::.:.|||:|:.:||.:|||.|:||||||.||..
 Worm   454 VPNEMMGTVNGLCSECRGERGEITSIDSTRLVILWRLPLAEVAVDFFERLKKLTSGYASFDYEPD 518

  Fly   576 GYHPSHLVRLDIHLNGKPVEELCRIVHVSKATGVARQMVLKLRELIPKQMVQIAIQACVGS--KV 638
            |:..:.||:|.|.:|.|.|.|..:|:..:.|...|:.:|.:|:..||:|..::.|:||:||  |.
 Worm   519 GWQDTRLVKLTILINSKEVSEFSQIIPAAMARDRAKILVQRLKREIPRQQFEVTIKACIGSSTKA 583

  Fly   639 LARETIKAYRKDVTAKLY----GGDVTRRMKLLKQQAEGKKKMRMFANIRVPHETFINVLKR 696
            |::..|:..::|.:..|.    ||.:.|..|.|..|.:||::|:|..|:::|.|.|:|||||
 Worm   584 LSQIVIQPMKRDFSQLLKGNFGGGGMERLNKKLSHQKKGKERMKMVGNVQIPKEAFLNVLKR 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
waw	NP_001027089.1	LepA	94..695	CDD:440249	281/612 (46%)
ZK1236.1	NP_498863.1	LepA	39..644	CDD:440249	281/610 (46%)