Protein Alignment cana and USO1

DIOPT Version :9

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_010225.1
• Gene: USO1 / 851501
• SGDID: S000002216
• Length: 1790
• Species: Saccharomyces cerevisiae
• Alignment Length: 1924
• Identity: 400/1924 - (20%)
• Similarity: 756/1924 - (39%)
• Gaps: 512/1924 - (26%)

  Fly    99 NPGVMVLAAKE-IFQQISSETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIH--------ESGN 154
            :|.|..|.|.| ||:::.|..|.:..||...:      :.|.|:..|..||.:        |:||
Yeast   216 SPHVQKLVAFENIFERLFSIIEEEGGLRGSLV------VNDCLSLINNILKYNTSNQTLFLETGN 274

  Fly   155 GIVNVNCKESIVTSEDDLLRQLYMGNKERVVGETNMNERSSRSHAIFRIIIE--SRKSDHSDNDT 217
                 ..|.:.:.||.....:::..|.:|:|   |:|....    |..:.:|  :..:....|..
Yeast   275 -----LPKLAHLLSEPISQDEVFFWNDQRIV---NINTALD----IVSLTVEPGNTVTTKHQNAL 327

  Fly   218 VKQSVLSLV-DLAGSEQVDPADHASSLMIFRNLVKS-----LSESVDSKPNSFRDSKLPRIMLPS 276
            :..|||.:| .||....:.......:|:...|:|:|     |..|....|  :.|..|| :...:
Yeast   328 LDSSVLMVVLRLAFFHNIPKKVRPVALLTAANMVRSNEHAQLEFSKIDVP--YFDPSLP-VNSTA 389

  Fly   277 LGGNVLTSIICTITPSFVEESSSTISFGT---CAKKIRC---------------KPQVCKIDSET 323
            .||.:....:.:|..:::..::|..:|.|   |::.::.               :.|:|...:..
Yeast   390 NGGPIKLIPVVSILINWMLYANSVHTFDTRVACSRLLKAYFMDNFDLQRDFLLKQVQLCNNSTNN 454

  Fly   324 TMMRQLDRGISMLKDKLAKKKIKNESQLVLQELEGRIKRDMLKIVSS--ASLD------------ 374
            ......:.|.|...||.:... |:.......|.||..|.::.:::.:  |.|:
Yeast   455 VGDNAKENGGSNKSDKESDSD-KDTDGKDGTEYEGSFKANLFEVLLNYDAELNLNPFKLFFTTDI 518

  Fly   375 -------DYRLQKRRRTWT---LTASGSEGDAPVLALPEPEE----------SRLPRPSKLTNLP 419
                   |::..:..|..|   .|.:..|.:.|:.|:....|          .|:| .|.||.|.
Yeast   519 FMFFFQQDHKYSEELREITRNVTTGNDLEDEEPLKAIQTISELLTTSLTAADIRIP-ISYLTFLI 582

  Fly   420 KPL---FQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQESVP 481
            ..|   |:........|.:.|:|.....|..:.|.           |...:.::::...|:.|..
Yeast   583 YWLFGDFKATNDFLSDKSVIKSLLSFSYQIQDEDV-----------TIKCLVTMLLGVAYEFSSK 636

  Fly   482 NCDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQME 546
            ....|:                           ||..|.:....||        :.:.::.||.:
Yeast   637 ESPFPR---------------------------KEYFEFITKTLGK--------DNYASRIKQFK 666

  Fly   547 EELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLELERLLPLA 611
            ::  |..|:.|                    ..||.:  :.|||:.
Yeast   667 KD--SYFSKVD--------------------MNEDSI--LTPELDE------------------- 688

  Fly   612 SASGLDSV--ACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQIS-TAHDDFG 673
              :||..|  :..|.||.:|      .:..:.:..||...|            |.|: .:.::..
Yeast   689 --TGLPKVYFSTYFIQLFNE------NIYRIRTALSHDPDE------------EPINKISFEEVE 733

  Fly   674 QLQEKYNNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRSDEQCQQLQDENSKLQAE 738
            :||.:...||.:.:|  |..:| :..:..:.:|.:.|.:|::.|    ||:.|.|...:|.|:..
Yeast   734 KLQRQCTKLKGEITS--LQTET-ESTHENLTEKLIALTNEHKEL----DEKYQILNSSHSSLKEN 791

  Fly   739 IGTLKERVEEIHSELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELMSTIQ 803
            ...|:..::.:...|.|:    |...|: |:.::.:.:.:.|:::                |||.
Yeast   792 FSILETELKNVRDSLDEM----TQLRDV-LETKDKENQTALLEYK----------------STIH 835

  Fly   804 ECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDYSGGRR 868
                 ::|...:|....||::.|.....|  |..|::..||.    .||:.:|.:|
Yeast   836 -----KQEDSIKTLEKGLETILSQKKKAE--DGINKMGKDLF----ALSREMQAVE--------- 880

  Fly   869 LFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDAS------DSVFLKGFLKCQRFQIVKINQE- 926
                                |..|.|:   |:.|.|      ::..||..:..:..:|..||:.
Yeast   881 --------------------ENCKNLQ---KEKDKSNVNHQKETKSLKEDIAAKITEIKAINENL 922

  Fly   927 -------QNLVKEEDRMRDIIFQLKQEVDGKKNLI----EEEKEVINN---LRAQITSLNQIETI 977
                   .||.||::.:...:.:.|.......||:    |:.|.:.||   ::|:..||  |:.:
Yeast   923 EEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESL--IKAV 985

  Fly   978 KNQNAKTKILCEELQTKDTVQTANKQESQ-EVLTLKTSLAHLKSKVCELQKKLEKQSEDEKISEL 1041
            :....::.|....||.|....:..|:..| |..:::.::..||..:.:|:     |:::|.||:.
Yeast   986 EESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLE-----QTKEEIISKS 1045

  Fly  1042 QSDIGEISECCLSMELKLADIVNWQAEELRPLDQLQESGVELQHHSTTAEESLNVEKPIQEQTER 1106
            .|...|.......::.||........|.:..:.:|.::..||       |..|...|.::.:.|.
Yeast  1046 DSSKDEYESQISLLKEKLETATTANDENVNKISELTKTREEL-------EAELAAYKNLKNELET 1103

  Fly  1107 TLTTEYERRIEQLEESLQRAQEELSILEKRKTDENKSLQLEYMAKIETSENENRSKFRAYCLDLK 1171
            .|.|. |:.:::::|:.:..:||...|||..|:..:.|. ...|.:|:.|.|:.        ||.
Yeast  1104 KLETS-EKALKEVKENEEHLKEEKIQLEKEATETKQQLN-SLRANLESLEKEHE--------DLA 1158

  Fly  1172 ETQKRYEEQL----QQTNEKLASVTTQCQVHLDVIKRSLQEKITQAEKERNELAVRHKAELEKIR 1232
            ...|:||||:    :|.||:::               .|.::||..::|.           |.|:
Yeast  1159 AQLKKYEEQIANKERQYNEEIS---------------QLNDEITSTQQEN-----------ESIK 1197

  Fly  1233 ETLKEKESSYKEKLRQAEEERDKEISRLEVMRNTIAELHKTNSDREVEL----EGVKMEKCQLKK 1293
            :...|.|...|.....:||:.:.:.|.::.:...|.||.|.|...|..|    :.|:.|..::|:
Yeast  1198 KKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKIKE 1262

  Fly  1294 LYD------KSMLELEQLQCTADQKSSDLLPGSSNENIDDLQKKCDQYVQDLELLRGEKAELLSE 1352
            |.|      |.:.|||.....::.|:|..|         :|||:.::..::|:   .:..||..:
Yeast  1263 LQDECNFKEKEVSELEDKLKASEDKNSKYL---------ELQKESEKIKEELD---AKTTELKIQ 1315

  Fly  1353 IQKINGQHSNTIKKLEEIEAEMITLTTQKELERCEIAEKLETFKSKEADIKEALHCAQLRLHAYD 1417
            ::||    :|..|..|:.|:|:..|......||....|:||..|::          .|::..|::
Yeast  1316 LEKI----TNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNE----------IQIKNQAFE 1366

  Fly  1418 KLVCEYERLKGCLSDSNKLSENLQKKVERLHAEQLALQEGISGRDSEIKQLRSELKDAIDENKTV 1482
            |     || |.....|:.:::...:|:..|..|.:.||.....:..||...||||:.....|..:
Yeast  1367 K-----ER-KLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDEL 1425

  Fly  1483 REAKVGLENSLKAVQENMSAQEGQFKQKIA-----------DIKGSVDELQIKLKSLQE----VR 1532
            .|.|   :|::|::|:.:.:    :|.||.           |.|..::.|:.:|::.||    |.
Yeast  1426 LEEK---QNTIKSLQDEILS----YKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVE 1483

  Fly  1533 DHLESRNEELKRKLKDAQELQNMVDK--------ERKLNSS---LREDFDKLEQTKLDLEEQLRA 1586
            :.|:...||..::..:.::.:.|:.|        |.:|.||   :|:..:||||:|...||.::.
Yeast  1484 EGLKKLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIKN 1548

  Fly  1587 KKVEIDRRSKELGEVTKDCENIRSDL--EAQTNDFLKE-RETLNLTISDLRLHNEQLLETSKNYL 1648
            .:.|.......:.|..||.|.::|.|  ||::...|:. ::.||.....:|::.|:
Yeast  1549 LQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEE--------- 1604

  Fly  1649 SDITAANNLNLEMKKNLHDLTKECKSLRSDLQSKEEYFQTQKQLLDETISNLKEENRKMEEKLSS 1713
                     |..:|..|.|:.:|.|..:::::|.:|    :|:||   .|.|||    :|::|.|
Yeast  1605 ---------NTVLKSKLEDIERELKDKQAEIKSNQE----EKELL---TSRLKE----LEQELDS 1649

  Fly  1714 GNKALKEDCEKLRSTLESKELILQQNKQELEERLTVINEKNGKNALLDAQLKSNETAFTSL---R 1775
            ..:..::..|:.|:.:..    .|..|.:|:|:..::                 ||.:..|   .
Yeast  1650 TQQKAQKSEEERRAEVRK----FQVEKSQLDEKAMLL-----------------ETKYNDLVNKE 1693

  Fly  1776 KAWIKQSLAIEAANKRSLEMEQKVDKRTREYEELRS-TLKTREINFRSEKERMDGTISSLLEDKR 1839
            :||.:..   :...|.:....|:::|..:|.:.|:: ..|.:|.|                ||:.
Yeast  1694 QAWKRDE---DTVKKTTDSQRQEIEKLAKELDNLKAENSKLKEAN----------------EDRS 1739

  Fly  1840 NLEEKLCTVTELLAKLKRELPALHTQKVNGGDVSIELNS 1878
            .:::.:..||:|     .|..|.:..|:.  |:.:|::|
Yeast  1740 EIDDLMLLVTDL-----DEKNAKYRSKLK--DLGVEISS 1771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	53/251 (21%)
		Motor_domain	8..310	CDD:277568	53/230 (23%)
		SMC_prok_B	<471..1270	CDD:274008	161/827 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316	183/781 (23%)
		CENP-H	1204..>1266	CDD:283493	12/61 (20%)
		CALCOCO1	<1489..1850	CDD:285171	84/393 (21%)
USO1	NP_010225.1	Uso1_p115_head	366..715	CDD:398505	73/450 (16%)
		M_group_A_cterm	783..>915	CDD:411361	34/195 (17%)
		Smc	898..1733	CDD:224117	222/976 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000