DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cana and AT5G42490

DIOPT Version :9

Sequence 1:	NP_001027247.1	Gene:	cana / 3771934	FlyBaseID:	FBgn0040233	Length:	1931	Species:	Drosophila melanogaster
Sequence 2:	NP_199064.1	Gene:	AT5G42490 / 834256	AraportID:	AT5G42490	Length:	1087	Species:	Arabidopsis thaliana

Alignment Length:	1272	Identity:	265/1272 - (20%)
Similarity:	453/1272 - (35%)	Gaps:	369/1272 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IQVCIKVRP-----------CEPGLTSLWQVKEGRSIQLADSHAE------PYVFDYVFDEGASN 56
            |.|.::|||           |:      |:.....:|...::..|      .|.||.||...:..
plant    10 ILVSVRVRPQNEKEKARNDICD------WECVNNTTIVCNNNLPERSLFPSTYTFDKVFGFDSPT 68

  Fly    57 QEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERD 121
            ::|::..||.:....:.|.|.:|||||||||||||||.      |:...|..:||..|...|:|.
plant    69 KQVYEDGAKEVALCVLGGINSSIFAYGQTSSGKTYTMC------GITKFAMDDIFCYIQKHTDRK 127

  Fly   122 FLLRVGYIEIYNEKIYDLLN-KKNQDLKIHESGNGIVNVNCKESIVTSEDDLLRQLYMGNKERVV 185
            |.|:...||||||.:.|||: ..||...:.:...|.|.....|..:.....|...|.:...:|.:
plant   128 FTLKFSAIEIYNEAVRDLLSGDNNQRRLLDDPERGTVVEKLIEETIQDRTHLEELLTVCETQRKI 192

  Fly   186 GETNMNERSSRSHAIFRIIIESRKSDHS-DNDTVKQSVLSLVDLAGSEQVDPADHASSLMIFRNL 249
            |||::||.|||||.|.|:.|||...::| |:.:...:.:..:||||||:..
plant   193 GETSLNEVSSRSHQILRLTIESTGREYSPDSSSTLAASVCFIDLAGSERAS-------------- 243

  Fly   250 VKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITPSFVEESSSTISFGTCAKKIRCKP 314
             ::||.....|..                        |.|       :.|.::.||..:|:|..|
plant   244 -QTLSAGTRLKEG------------------------CHI-------NRSLLTLGTVIRKLRFDP 276

  Fly   315 QVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNESQLVLQELEGRIKRDMLKIVSSASLD-DYRL 378
              |.|                     |:.:::|..:...:|...|:  |...:.||...| |:
plant   277 --CDI---------------------AQSQVENLLKSTAEERSSRM--DEQSMFSSMDFDADF-- 314

  Fly   379 QKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTNLPK--------------------PLF 423
              |||::..|..|                   .||.:.||.:                    |.|
plant   315 --RRRSYDSTDLG-------------------EPSIINNLTERNFEFLENSEEDDFLLDDKTPQF 358

  Fly   424 QRRGI-----------APKAKGICKTLKEKRLQTDNMDTMPGRAKQLGR--ETASRIP-SVMMSK 474
            .|..:           ..:.:..||.::....:.:.....|...:....  :...:|. |.::|.
plant   359 SRHNLYDDWEELVQITDERLEDACKEVRCIEPEAEQSSGQPAACESHDSLDDIVDKIAISEVLSP 423

  Fly   475 KYQESVPNCDAPQTEISALTASNQVAKETIEKYEEQVKRLK-ETIERLEME--------NGKAVN 530
            :.:|::|..:..|    :...|..:.|...|..|..:...| ||:..||.|        |.:|.|
plant   424 RKEETLPGLEHEQ----SYNPSTGIEKAENEDMEISIPAAKEETLPALEYEQSYNSYTGNERAEN 484

  Fly   531 LGEQFET----------------------HKAKSKQMEEELLSSISEKDSTIVSLQ----QSLEE 569
            ...:..|                      .||:::.||   :|:.:||::..:||:    .:..|
plant   485 EVMEISTPRKDEPLSALEYEQSYNSSTSNEKAENEDME---ISTPAEKENVDLSLKTIDVNAKPE 546

  Fly   570 LSRDVLRNS------------------KEDQM----RSMCPELESSCERICNKCLELERLLPLAS 612
            .....|:||                  :|:||    |.|.|..:.:     .:||..|
plant   547 TYELTLKNSDLEIGPSVEAQESQESVNEEEQMKNEERKMSPSTKQA-----EQCLNKE------- 599

  Fly   613 ASGLDSVACQFDQLRSEIAATR-MKLESM-LSTFSHASCEVSQKTTDCKRLSEQISTAHD--DFG 673
                       :..:||..:|. .:|.|: ::..|.|:.||.....|.| |.|. :|:.|  :..
plant   600 -----------ENAQSEQQSTEDCELNSLPINNQSEATVEVELTPNDAK-LDED-ATSRDKWESK 651

  Fly   674 QLQEKYNNLKHKWSSQKLAIDTMQVD-YNTIQQKYLQLQDEYRHL-ELRSDEQCQQLQ-DENSKL 735
            |.||...:.......:.:..|....| |..:::|..::|.:..:| .:.:.||.|... ..:.|.
plant   652 QQQEADKDCNESSVCKNIGTDDNDNDTYMALKEKVKEMQKKIEYLMSMHTAEQQQSPSFRRDFKS 716

  Fly   736 QAEIGTLKERVEEIHSELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELMS 800
            ..|..|.| |.......||.|.:|                     .| |:.::     :||....
plant   717 PPEYFTAK-RSRSCRENLLSVRSP---------------------HW-FESLE-----VSNNTSP 753

  Fly   801 TIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDYSG 865
            |.:.........:..|::...:|..|:.:.|...   .:.|.::...|.:....::::....:|
plant   754 TWRVMQTKASPGRPNTSSISFDSGSSTSIDTRSL---KDYDPEMGNSFREFVAGLEEMAKKHHS- 814

  Fly   866 GRRLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVKINQEQNLV 930
                 |.:..|.|..:|     ..|.|....:.:....:|||  :|             .|..|.
plant   815 -----IDSTPELDYGIP-----YAPTKTERMEIRPESPADSV--RG-------------NENALP 854

  Fly   931 KEEDRMRDIIFQLKQEVDGKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILCEELQTKD 995
            ..:|                  :.:|..:..||              ::|..:.....||.:.|:
plant   855 NPQD------------------INKETTDATNN--------------QSQREQVGDSVEEAKPKE 887

  Fly   996 TVQTANKQESQEVLTLKTSLAHLKSKVCELQKKLEKQSEDEKISELQSDIGEISECCLSMELKLA 1060
            |..|...||..:|..  .....:.|...|.|::        ||.||.      :.|.:.:..:..
plant   888 TDSTEASQEKLQVAA--NGQYSISSSDFERQQR--------KIIELW------AACNVPLVHRTY 936

  Fly  1061 DIVNWQAEELRPLDQLQESGVELQHHSTTAEESLNVEKPIQEQTERTLTTEYERRIEQLEESLQR 1125
            ..:.::.:   |.|.:... |||:..|...:...|..:..:.||.:.||.|.|...:||.:....
plant   937 FFLLFKGD---PSDYVYME-VELRRLSFLKQTISNDMETSRMQTVKALTREKEWISKQLPKKFPW 997

  Fly  1126 AQEELSILEKRKTDEN---KSLQLEYMAKIETSENEN 1159
            .| .:.:.:|...:.|   :|||:.:.....|.:.::
plant   998 NQ-RIGLYQKWGVEVNSKQRSLQVAHKLWTNTQDMDH 1033

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	94/325 (29%)
		Motor_domain	8..310	CDD:277568	91/319 (29%)
		SMC_prok_B	<471..1270	CDD:274008	143/756 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316	45/239 (19%)
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171
AT5G42490	NP_199064.1	Motor_domain	9..272	CDD:277568	91/319 (29%)
AT5G42490	NP_199064.1	DUF3490	913..1065	CDD:288820	29/140 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47968
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.960