DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cana and TES

DIOPT Version :9

Sequence 1:	NP_001027247.1	Gene:	cana / 3771934	FlyBaseID:	FBgn0040233	Length:	1931	Species:	Drosophila melanogaster
Sequence 2:	NP_001319676.1	Gene:	TES / 823396	AraportID:	AT3G43210	Length:	938	Species:	Arabidopsis thaliana

Alignment Length:	1045	Identity:	254/1045 - (24%)
Similarity:	428/1045 - (40%)	Gaps:	228/1045 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IQVCIKVRPC---EPGLTSL--WQVKEGRSIQL----ADSHAEPYVFDYVFDEGASNQEVFDRMA 64
            |.|.:::||.   |.....|  |:..:..:|..    .|.....|.||.||:...:.|||::..:
plant    30 ILVTVRMRPLNWREHAKYDLIAWECPDDETIVFKNPNPDKAPTKYSFDKVFEPTCATQEVYEGGS 94

  Fly    65 KHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYI 129
            :.:..:.:.|:|.|||||||||||||:||.      ||.....|:|::.|....||.|:|:|..:
plant    95 RDVALSALAGTNATIFAYGQTSSGKTFTMR------GVTESVVKDIYEHIRKTQERSFVLKVSAL 153

  Fly   130 EIYNEKIYDLLNKKNQDLK-IHESGNGIVNVNCKESIVTSEDDLLRQLYMGNKERVVGETNMNER 193
            |||||.:.||||:....|: :.:...|.:..|..|.:|.|...|...:.:...:|.||||.:|::
plant   154 EIYNETVVDLLNRDTGPLRLLDDPEKGTIVENLVEEVVESRQHLQHLISICEDQRQVGETALNDK 218

  Fly   194 SSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSE----------QVDPADHAS-SLMIFR 247
            |||||.|.|:.|.|...:.:.......:.|:||||||||          ::....|.: ||:...
plant   219 SSRSHQIIRLTIHSSLREIAGCVQSFMATLNLVDLAGSERAFQTNADGLRLKEGSHINRSLLTLT 283

  Fly   248 NLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITP--SFVEESSSTISFGTCAKKI 310
            .:::.||.........:|||||.||:..|||||..|:|||||:|  |.||::..|:||...||::
plant   284 TVIRKLSSGRKRDHVPYRDSKLTRILQNSLGGNARTAIICTISPALSHVEQTKKTLSFAMSAKEV 348

  Fly   311 RCKPQVCKIDSETTMMRQLDRGISMLKDKLAK---------KKIKNESQLVLQELEGRIK----- 361
            ....:|..:.||..:::.|.:.::.|:.:|..         |.:..|.::.:|::|..:|
plant   349 TNCAKVNMVVSEKKLLKHLQQKVAKLESELRSPEPSSSTCLKSLLIEKEMKIQQMESEMKELKRQ 413

  Fly   362 RDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGD-----APVLALPEPEESRLPRPSKLTNLPKP 421
            ||    ::.:.||..|..|.|:      ..||.:     |..|:....|||   .|||
plant   414 RD----IAQSELDLERKAKERK------GSSECEPFSQVARCLSYHTKEES---IPSK------- 458

  Fly   422 LFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQ-----ESVP 481
                  ..|.::   :|.:::|  .||:     |......:..:.:..:.:.:|:|     |:..
plant   459 ------SVPSSR---RTARDRR--KDNV-----RQSLTSADPTALVQEIRLLEKHQKKLGEEANQ 507

  Fly   482 NCDAPQTEISALTASNQVAKETIEKYEEQVKRL-KETIERLEMENGKAVNLGEQFETHKAKSKQM 545
            ..|....|:::....:|.|.|.:.|...:::.: |..:...|:..|...||.|:.....::....
plant   508 ALDLIHKEVTSHKLGDQQAAEKVAKMLSEIRDMQKSNLLTEEIVVGDKANLKEEINRLNSQEIAA 572

  Fly   546 EEELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQM----RSMCPELESSCERICNKCLELER 606
            .|:.|..:......:||..|: :|.:.|.....|:.::    .|..|.|:......|:.....|.
plant   573 LEKKLECVQNTIDMLVSSFQT-DEQTPDFRTQVKKKRLLPFGLSNSPNLQHMIRGPCSPLSGTEN 636

  Fly   607 LLPLASASGLDSVACQFDQLRSEIAATRMKL-ESMLSTFSHASCEVSQK--TTDCKRLSEQISTA 668
            ..|.::....:|....|       .||..|. ::...|.|.....||::  :.|.||::.....|
plant   637 KDPESNVVSANSAPVSF-------GATPPKRDDNRCRTQSREGTPVSRQANSVDIKRMNRMYKNA 694

  Fly   669 HDDFGQLQEKYNNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRSDEQCQQLQDENS 733
                  .:|...|:|...:..|..:..:|      .||.|.:              ||.|:.|.:
plant   695 ------AEENIRNIKSYVTGLKERVAKLQ------YQKQLLV--------------CQVLELEAN 733

  Fly   734 KLQAEIGTLKERVEEIHSELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNEL 798
                |.|...|......|::           |..|..:|.:|::..| |....|.:.:......|
plant   734 ----ETGAASEYDATDESQM-----------DWPLCFEEQRKQIIML-WHLCHISIIHRTQFYML 782

  Fly   799 MSTIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDY 863
            ..                                 .||.:::              ..::||
plant   783 FK---------------------------------GDPADQI--------------YMEVEL--- 797

  Fly   864 SGGRRL-FIYNH-AEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVK-INQ 925
               ||| ::..| ||...:.|:| |..|||.|:....:.            ||.:|..:.| :|.
plant   798 ---RRLTWLEQHLAELGNASPAL-LGDEPASYVASSIRA------------LKQEREYLAKRVNT 846

  Fly   926 EQNLVKEEDRMRDIIFQLKQEVD--GKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILC 988
            :  |..||   |:::: ||.:|.  ||    :..::.||.|.....::..:.......||....|
plant   847 K--LGAEE---REMLY-LKWDVPPVGK----QRRQQFINKLWTDPHNMQHVRESAEIVAKLVGFC 901

  Fly   989 EELQT 993
            :..:|
plant   902 DSGET 906

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	116/329 (35%)
		Motor_domain	8..310	CDD:277568	116/323 (36%)
		SMC_prok_B	<471..1270	CDD:274008	104/541 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316	17/72 (24%)
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171
TES	NP_001319676.1	KISc_CENP_E	29..348	CDD:276825	116/323 (36%)
		Smc	<364..>585	CDD:224117	48/256 (19%)
		DUF3490	755..919	CDD:403272	44/229 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47968
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.960