Protein Alignment cana and POK2

DIOPT Version :10

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_188535.4
• Gene: POK2 / 821439
• AraportID: AT3G19050
• Length: 2771
• Species: Arabidopsis thaliana
• Alignment Length: 2337
• Identity: 528/2337 - (22%)
• Similarity: 924/2337 - (39%)
• Gaps: 643/2337 - (27%)

  Fly     8 SIQVCIKVRPCEPGLTSLWQVKEG--RSIQLADSHAEPYV--------FDYVFDEGASNQEVFDR 62
            ::|:.|:|||    |.|:.:...|  |.::...|....::        ||:|..|....:.:|..
plant   193 NVQILIRVRP----LNSMERSINGYNRCLKQESSQCVAWIGPPETRFQFDHVACETIDQETLFRV 253

  Fly    63 MAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGD--------EQNPGVMVLAAKEIFQQISSETE 119
            ....:|..|:.|.|..|||||||.|||||||:|:        ..|.|:|....:.:|.:|.:|.|
plant   254 AGLPMVENCLSGYNSCIFAYGQTGSGKTYTMLGEVGDLEFKPSPNRGMMPRIFEFLFARIQAEEE 318

  Fly   120 --RD----FLLRVGYIEIYNEKIYDLLNKKNQDLKIHES-GNGIVNVNCKESIVTSEDDLLRQLY 177
              ||    :..:..::|||||:|.|||...:.:|::.|. .:|:...|..|..|.|..|:|..:.
plant   319 SRRDERLKYNCKCSFLEIYNEQITDLLEPSSTNLQLREDIKSGVYVENLTECEVQSVQDILGLIT 383

  Fly   178 MGNKERVVGETNMNERSSRSHAIFRIIIESR-KSDHSDNDTVKQSVLSLVDLAGSEQ-------- 233
            .|:..|.||.||||..|||||::|..:|||| :.|.:.|  ::.:.|:||||||||:
plant   384 QGSLNRRVGATNMNRESSRSHSVFTCVIESRWEKDSTAN--MRFARLNLVDLAGSERQKTSGAEG 446

  Fly   234 ---VDPADHASSLMIFRNLVKSLSESVDSKPN--SFRDSKLPRIMLPSLGGNVLTSIICTITPSF 293
               .:.|....||....:::..|.:..:.||.  .:|||:|..::..|||||..|.||...:||.
plant   447 DRLKEAASINKSLSTLGHVIMVLVDVANGKPRHIPYRDSRLTFLLQDSLGGNSKTMIIANASPSV 511

  Fly   294 --VEESSSTISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKN--------- 347
              ..|:.:|:.|...||.|:....|.:..:|..:  :|.|.|.:||::|:..|.:|
plant   512 SCAAETLNTLKFAQRAKLIQNNAVVNEDSNEDVL--ELRRQIRLLKEELSLLKRQNISRALSFGS 574

  Fly   348 ------ESQL-----VLQELEGRIKRDMLKIVSSASLDDYRL-QKRRRTWTLTASGS-----EGD 395
                  |||:     |:.| .|:.:...|.:..|...  .|: :|:.::..:|.:||     ..|
plant   575 ATANFAESQVDSPSSVMHE-TGQQQAGNLLVYESGGC--VRMSRKQLKSLEITLAGSLRREHVAD 636

  Fly   396 APVLALPEPEESRLPRPSKLTNLPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLG 460
            |.:..| |.|...|.|          |.::|....::..:....:|.::|
plant   637 ASIKKL-EAEIEHLNR----------LVRQREEDTRSTKMMLRFREDKIQ--------------- 675

  Fly   461 RETASRIPSVMMSKKYQESVPNCDAPQTEISA---LTASNQVAKETIEKYEEQVKRLKETIERLE 522
                 |:.|::               ...|||   |...|.|..|.|:..:.::.:..| :.|..
plant   676 -----RLESLL---------------GNHISADSFLLEENNVLSEEIQLLQAKIDKNPE-LTRFA 719

  Fly   523 MENGKAVNLGEQFETHKAKSKQMEEELLSSISEKDSTIVSLQQSLEELS------------RDVL 575
            :||   :.|.:|....:...::.|.|:|  :.|..:....|.|.|:|.|            :...
plant   720 LEN---IRLLDQLRRFQEFYEEGEREIL--LGEVSNLRNQLFQFLDENSDWQKHVDDGIEPQGAS 779

  Fly   576 RNSKE-----DQMRSMCPELESSCERICNKCLE----LERLLPLASASGLDSVACQFDQLRSEIA 631
            |.|||     ::::..|.||| .|......|||    |.|.:....|...|..||..|:..|.
plant   780 RMSKENCSLQEELKKTCYELE-KCRSNLGSCLEENAKLSREINDLQAMVSDIRACTPDEHSSV-- 841

  Fly   632 ATRMKLESMLST-----FSHASCEVS---------------QK-----------TTDCK--RLSE 663
               .|.:::|.|     ....:||.:               ||           .|:.:  ||..
plant   842 ---NKQKALLGTQNFEPHETLACEQANYVEEIIKLQLDLDVQKIILDEERTLRGDTEAQAVRLKF 903

  Fly   664 QISTAHDDFGQLQEKYNNLKHKWSSQKLAIDTMQ----------VDYNTIQQKYLQ-LQDEYRHL 717
            .|....|....:.::..|:..:....|.|:..::          |:...|::.|.: |:.:...:
plant   904 DIEVLKDQLLLISKQQKNVYSELGETKSAVAALESQNIILIQEAVELRRIKENYFELLKKQELDI 968

  Fly   718 ELRSDEQCQQLQD---ENS-------KLQAEIGTLKERVEEIHSELLEVPNPDTHPEDME----- 767
            .....:||.:.:|   |:|       |:||.:...| |:..::..  ::.:.....|:|:
plant   969 PAMKSKQCDEFKDNPAEDSEIDTKFKKMQASLEKAK-RLNMLYKS--DIASKACGDEEMDEVCKQ 1030

  Fly   768 -----------LQNQ-----------ELKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALRE 810
                       |||:           :.|:.:::.|.|..|.|:  |.|.::|..|..:.:.|:|
plant  1031 AEAATAEVIVCLQNELEVLQKEVNDFQSKENVTEKQVEILETQM--EELQDKLRDTTMDNEQLQE 1093

  Fly   811 E------------HKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSI--QQIELT 861
            :            ::.....|:||.:..:|         ||..||...|...:|.|:  ::|.::
plant  1094 QLRGKDMELLIISNEMELLTSELEEILLNG---------NEGLTDACYQADLISGSLPDKRIWIS 1149

  Fly   862 DYSGGRRLFIYNHAEQDQSVPSLKLCLEPA-----------KYLEG------DGKQHD----ASD 905
            :..||   .|...:|::..:..|:.|||.|           |.|:|      :..|.:    .:|
plant  1150 EQVGG---LIRTLSERELMIEDLESCLEDANKKRCDIESMLKSLKGAAIVMNEAHQREFEEKETD 1211

  Fly   906 SVFLKGFLKCQRFQIV-----KINQEQNLVKEE-----------DRMRDI----IFQLKQEVDGK 950
            .:.||..| |.:.:.:     |:...:.|:.|.           :|..::    .|:|||    |
plant  1212 VLLLKSQL-CTKTETILRLQEKLKMAERLIYEASDCATASLIIVNRYSEVTESHTFELKQ----K 1271

  Fly   951 KNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILCEELQTKDTVQTANKQESQEVLTLKTSL 1015
            ...:.|....|.:|:.|:..|.  .|.|  ..::|:|.||.......|...:.|...:..:|..|
plant  1272 DFQVAESTGTILSLKQQVQDLE--ATCK--EFRSKLLEEEKNASAMEQKLEEIEETSISAMKEKL 1332

  Fly  1016 AHLKSKVCELQKKLEKQSEDEKISELQSDIGEISECCLSMELKLADIVNWQAEELRPLDQLQESG 1080
            :.||..|.:|:..:....|.:|.:|.::.:...:.|....| ...::|.....|..|.:...||
plant  1333 SELKGGVSDLRSCITMCQEHDKYTEAENSLSSPAHCSEGQE-PGRNVVVSSCIEKTPNNNHTES- 1395

  Fly  1081 VELQHHSTTAEESLNVEKPIQEQTERTLTTEYERRIEQLEESLQRAQEELSILEKRKTDENKSLQ 1145
              ::..|..:.|...|...::::.|..|.:..|.::|.  .:|:..:|||...|||.......|.
plant  1396 --MRLSSKVSSERGKVIILLKQEMESALASLKEVQVEM--ANLKGEKEELKASEKRSLSNLNDLA 1456

  Fly  1146 LEYMAKIETSENENRSKFRAYCLDLKETQKRYEEQLQQTNEKLASV---TTQCQVHLD------- 1200
            .: :..:.|.              :...:::||.:::.|:.||.::   ..:.::..|
plant  1457 AQ-ICNLNTV--------------MSNMEEQYEHKMEVTDHKLKTLEHEIAKMKIEADQEYVENL 1506

  Fly  1201 -VIKR--SLQEKITQAEKERNELAVRH---------------------KAELEKIRE----TLKE 1237
             ::|:  ..|..|.:|:...|||.:.:                     ||.:||::|    .:||
plant  1507 CILKKFEEAQGTIREADITVNELVIANEKMRFDLEKQKKRGISLVGEKKALVEKLQELESINVKE 1571

  Fly  1238 KES-SYKEKL-------------------RQAEEERD-------KEISRLE-------------- 1261
            .|. :|.|||                   |:.::|..       |::|.|:
plant  1572 NEKLAYLEKLFESSLMGIGNLVEELATVVRKLQDESSVALTGMAKDLSELKSWVSETNSARLFLE 1636

  Fly  1262 ------VMRN-TIAELH------------KTNSDREVELEGVKMEKCQLKKLYDKSMLELEQLQC 1307
                  :|:: .|:.||            ..|::..:...|:.:....:..|.|.::....:|:.
plant  1637 DIWSEIIMKDCAISVLHLCHMGILLETVTGINTENGLLQRGLCVSNSSIAGLRDNNLRLRRELEM 1701

  Fly  1308 TADQKS---SDLLPG----SSNENIDDL---------QKKCD-QYVQDLELLR----GEKAE-LL 1350
            .|:.|.   :|:..|    |.||...:|         ||... ||.:||.|.|    |.:.: ||
plant  1702 FANLKGKLLTDIKNGFERISRNEEATNLLTTKLSSFDQKISGLQYQEDLMLQRSNSMGSQLDILL 1766

  Fly  1351 SEIQKINGQHSNTIKKLE------------EIEAEMITLTTQKELERCEIAEKLETFKSKEA--- 1400
            .||...||..:.|:.:.|            |::..::.|.: |::|...:|:..:.:.|..|
plant  1767 KEIDLSNGDLAETLLEQERHLNQKNDFFDTEVQLYLMDLCS-KDVELLVLAQTAKEYSSCLAVVD 1830

  Fly  1401 -----------DIKEALHCAQLRLHAYDKLVCEYERLKGCLSDSNKLSENLQKKVERLHAEQLAL 1454
                       |:||.|..:|:          |.|....||.| |||             |.:::
plant  1831 RELLDHHVIVEDLKEKLIVSQV----------EGELKDQCLVD-NKL-------------ETVSV 1871

  Fly  1455 QEGISGRDSEIKQLRSELKDA------IDE-NKTVREAKVGLENSLKAVQENMSAQEGQFKQKIA 1512
            :|.::...|:||.|.|:|..:      ||| ||...|..:.||:|:..:|:
plant  1872 KEELTEAQSKIKVLSSDLDRSVQKIAEIDEVNKDFGERVIFLESSITGLQQ-------------- 1922

  Fly  1513 DIKGSVDELQIKLKSLQEVRDHLESRNEELKRKLKDAQELQNMVDKERKLNSSLR--------ED 1569
                   ||.:|...|..:........|||..|.:|.|...::|...:|.|.||:        :.
plant  1923 -------ELAMKASELYSLEHSRSVTAEELDIKERDVQVYADIVSSLKKENVSLKNKFIHFGEDQ 1980

  Fly  1570 FDKLEQTKLDLEEQLRAKKVEIDRRSKELGEVTKD------------CENI-RSDLEAQTNDFLK 1621
            |..|:.|:|.:     ||...:...||:|.::|:|            |||: ::.:.|.|...|
plant  1981 FKALDVTRLSI-----AKCSHLTEDSKKLEKLTRDGMAISDKMLQLICENVDKASVFADTVQSL- 2039

  Fly  1622 ERETLNLTISDLRLHNEQLLETSKNYLSDITAANNLNLEMKKNLHDLTKECKSLRSDLQSKEEYF 1686
            :.:...|...:|.||:|.|  ...:.|..::...:|..|...|..|...|.|.:...:::.|:..
plant  2040 QIDVQELLSENLNLHDELL--RKDDVLKGLSFDLSLLQESASNSRDKKDETKEIMVHVEALEKTL 2102

  Fly  1687 QTQKQLLDETIS-----------------NLK---EENRKMEEKLSSGNKALKEDCEKL---RST 1728
            ..:...|::.:|                 ||:   |:.||.:||||:.||.::.:.|.|   :.:
plant  2103 ALKTFELEDAVSHAQMLEVRLQESKEITRNLEVDTEKARKCQEKLSAENKDIRAEAEDLLAEKCS 2167

  Fly  1729 LESKELILQQNKQELEERLTVINEKNGKNALLD----AQLKSNET---------AFTSLRKAWIK 1780
            ||  |.::|..|......:.:.|.:|....|.|    .|.|.|:.         ...:|::.:.|
plant  2168 LE--EEMIQTKKVSESMEMELFNLRNALGQLNDTVAFTQRKLNDAIDERDNLQDEVLNLKEEFGK 2230

  Fly  1781 QSLAIEAANKRSLEMEQ-------KVDKRTRE-------YEELRSTL-----KTREINFRSEKER 1826
            .....:....|.:|.:|       ..|:|..|       .|||..|:     |...:...:|::|
plant  2231 MKSEAKEMEARYIEAQQIAESRKTYADEREEEVKLLEGSVEELEYTINVLENKVNVVKDEAERQR 2295

  Fly  1827 MD--------GTISSLLEDKRNLEEKLCTVTEL----LAKLKRELPALHTQKVNGGDVSIEL 1876
            :.        .||...:|..||.:|::..:.:.    ||:.|:.:.||..   |..|...|:
plant  2296 LQREELEMELHTIRQQMESARNADEEMKRILDEKHMDLAQAKKHIEALER---NTADQKTEI 2354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	Motor_domain	8..310	CDD:473979	115/342 (34%)
		CCDC158	<505..>729	CDD:464943	56/288 (19%)
		SMC_prok_B	622..1285	CDD:274008	167/896 (19%)
		SMC_prok_B	1110..1875	CDD:274008	214/1005 (21%)
POK2	NP_188535.4	Motor_domain	192..540	CDD:473979	117/352 (33%)
		PLN03188	<614..>763	CDD:215621	39/200 (20%)
		SMC_prok_B	615..>1344	CDD:274008	163/812 (20%)
		SMC_N	<1262..1598	CDD:481474	75/364 (21%)
		SMC_prok_B	<1674..2384	CDD:274008	169/740 (23%)
		Smc	<2131..>2674	CDD:440809	54/229 (24%)