DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cana and AT2G21300

DIOPT Version :9

Sequence 1:	NP_001027247.1	Gene:	cana / 3771934	FlyBaseID:	FBgn0040233	Length:	1931	Species:	Drosophila melanogaster
Sequence 2:	NP_001031385.1	Gene:	AT2G21300 / 816669	AraportID:	AT2G21300	Length:	862	Species:	Arabidopsis thaliana

Alignment Length:	834	Identity:	201/834 - (24%)
Similarity:	348/834 - (41%)	Gaps:	204/834 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IQVCIKVRP---------------CEPGLTSLWQ--VKEGRSIQLADSHAEPYVFDYVFDEGASN 56
            |.|.:::||               |....|.|::  ::||.:...|      |.||.|:......
plant    25 ILVLVRLRPLNEKEILANEAADWECINDTTVLYRNTLREGSTFPSA------YSFDRVYRGECPT 83

  Fly    57 QEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERD 121
            ::|::...|.:..:.::|.|.:|||||||||||||||      .|:...|..:||..|....:|.
plant    84 RQVYEDGPKEVALSVVKGINSSIFAYGQTSSGKTYTM------SGITEFAVADIFDYIFKHEDRA 142

  Fly   122 FLLRVGYIEIYNEKIYDLLNKKNQDLKIHES-GNGIVNVNCKESIVTSEDDLLRQLYMGNKERVV 185
            |:::...||||||.|.|||:..:..|::.:. ..|.......|..:...:.|...:.:...:|.:
plant   143 FVVKFSAIEIYNEAIRDLLSPDSTPLRLRDDPEKGAAVEKATEETLRDWNHLKELISVCEAQRKI 207

  Fly   186 GETNMNERSSRSHAIFRIIIES--RKSDHSDNDTVKQSVLSLVDLAGSEQVDPADHAS------- 241
            |||::||||||||.|.::.:||  |:....:|.|...:.::.:||||||:...|..|.
plant   208 GETSLNERSSRSHQIIKLTVESSAREFLGKENSTTLMASVNFIDLAGSERASQALSAGARLKEGC 272

  Fly   242 ----SLMIFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITP--SFVEESSST 300
                ||:....:::.||.......| :|||||.||:.|.||||..|:|:||::|  |.||::.:|
plant   273 HINRSLLTLGTVIRKLSNGRQGHIN-YRDSKLTRILQPCLGGNARTAIVCTLSPARSHVEQTRNT 336

  Fly   301 ISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNES----------QLVLQE 355
            :.|..|||::..|.|:..:.|:..:::||.|.::.|:.:|........|          .|.:|:
plant   337 LLFACCAKEVTTKAQINVVMSDKALVKQLQRELARLESELRNPAPATSSCDCGVTLRKKDLQIQK 401

  Fly   356 LEGRI-----KRDMLKIVSSASLDDY---------------RLQKRRRTWTLTASGSEGDAPVLA 400
            :|.::     :||    ::.:.|:|:               ..:.|...|   ..||..:  :..
plant   402 MEKQLAEMTKQRD----IAQSRLEDFMKMVEHDASSKAGTPHFRNRTNKW---EDGSVSE--ISG 457

  Fly   401 LPEPEESRLPRPSKLTNLPKPLFQRRG-------------IAPKAKG-----ICKTLK------- 440
            :.:|:.:........|    ||...|.             ::|:..|     .||.::
plant   458 VVDPDRTSFISDGTST----PLSTARAHVRSHSDDDLEEEMSPRHSGDQSEEYCKEVQCIEMEES 518

  Fly   441 ------EKRLQTDNMDTMPGRAKQLGRETAS---RIPSVMMSKKYQE-----------SVPNCDA 485
                  :...:|| .:|:.|...:...||.|   ||||.:.|.:.::           |.|. ||
plant   519 TRDINNDSEERTD-AETLLGHNAEANGETGSAQHRIPSSVRSVRRRKSWSRGDTMTGTSTPP-DA 581

  Fly   486 PQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLG-EQFETHKAKSKQMEEE- 548
            .:|:.......:..|...:| :....|.|:         |....:.| :..|.|...:..:.||
plant   582 LETDYRGRPEGHGFAFPDLE-FGSGGKLLR---------NDSMTSRGSDSTEAHSIGTPLVGEEG 636

  Fly   549 ---LLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQ----MRSMCPELESSCERI------CNK 600
               .:.|..|....:||..::..::.:|:..::.|::    |.:...|.|...|:|      |:.
plant   637 GITSIRSFVEGLKEMVSDPENSGKMRKDIGVDAMEEEVSGTMTNWSEEFERQREQILGLWQTCHV 701

  Fly   601 CL----------------------ELERLLPLASASGLDSVACQFDQLRSEIAATRMKL----ES 639
            .|                      ||.||..:..:....:.|  |::.::...|:.:|.    ..
plant   702 SLVHRTYFFLLFTGDQADSIYIGVELRRLSFMKESFSQGNHA--FERGQTLTIASSLKALHRERR 764

  Fly   640 MLSTFSHASCEVSQKTT--DCKRLSEQISTAHDD-------FGQLQEKYNNLKH 684
            |||..      |.::.|  :.|||.::...|.:.       ..||..|.|::.|
plant   765 MLSKL------VGKRFTGEERKRLYQKFGIAVNSKRRRLQLANQLWSKPNDITH 812

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	111/339 (33%)
		Motor_domain	8..310	CDD:277568	110/333 (33%)
		SMC_prok_B	<471..1270	CDD:274008	51/275 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171
AT2G21300	NP_001031385.1	KISc_CENP_E	24..346	CDD:276825	110/333 (33%)
		Kinesin	30..346	CDD:278646	108/328 (33%)
		DUF3490	685..844	CDD:288820	27/136 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47968
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.960