Protein Alignment cana and kif19

DIOPT Version :10

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: XP_005156460.1
• Gene: kif19 / 565913
• ZFINID: ZDB-GENE-080215-2
• Length: 1015
• Species: Danio rerio
• Alignment Length: 981
• Identity: 230/981 - (23%)
• Similarity: 395/981 - (40%)
• Gaps: 238/981 - (24%)

  Fly     9 IQVCIKVRP-----CEPGLTSLWQVKEGRSIQLADSHAEP-------------YVFDYVFDEGAS 55
            :.|.:::||     .|.|.|.:....:.:.:.|.|...:|             |:||..||..|:
Zfish    12 LTVALRIRPLSDAELEEGATIIAHKVDDQMVVLLDPMEDPDDILRAHRSREKTYMFDVAFDYSAT 76

  Fly    56 NQEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETER 120
            ..||:....|.::...:.|.|.|:||||.|..||||||:|.::.||:.|....::|:.| .||..
Zfish    77 QDEVYRYTTKGLIEGLISGYNATVFAYGPTGCGKTYTMLGTDREPGIYVRTLNDLFKAI-EETSD 140

  Fly   121 D--FLLRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNV-NCKESIVTSEDDLLRQLYMGNKE 182
            |  :.:.:.|:|||||.|.||||..:..|.:.|...|.:.| ...|....:..:::..|..|||:
Zfish   141 DMQYSVSMSYLEIYNEMIRDLLNPSSGFLDLREDSKGEIQVAGITEVSTINAREIMELLMKGNKQ 205

  Fly   183 RVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQVDPADHAS------ 241
            |....|..|:.||||||:.::::..:.........|:.:.|.::||||||:.....:..
Zfish   206 RTQEPTAANQTSSRSHAVLQVVVRQQSRCRDILQEVRFARLFMIDLAGSERASQTQNRGQRLKEG 270

  Fly   242 -----SLMIFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITPSFV--EESSS 299
                 ||:...|.:.:|||...:|..::|||||.|::..|||||..|.:|..|:|:.:  |:|.:
Zfish   271 AHINRSLLALGNCINALSEKNGNKYVNYRDSKLTRLLKDSLGGNSRTVMIAHISPASLAFEDSRN 335

  Fly   300 TISFGTCAKKIRCKPQ------VCKIDSETTMMRQLDRGISMLKDKLAKKKIK--NESQLVLQEL 356
            |:::...||.||.:.:      ...|...|:::..|...|..||.|:|.:..:  |..:..::.:
Zfish   336 TLTYADRAKSIRTRVKRNLLNVSYHIAQYTSIISDLRSEIQRLKKKIADQASRQINPDRTDIRHV 400

  Fly   357 ----------EGRIKRDMLKIVSSASLDDYRLQK--RRRTWTLTASGSE----GDAPVLALPEPE 405
                      :.|.:.|.|:   ...:|.:|.|.  |:|...|..|..|    ....:|.:.:.|
Zfish   401 QAEVQAHSSQQSRAEMDQLR---EQLIDAFRQQMDIRKRLMELDNSNMEIQIDTSKHLLTIADWE 462

  Fly   406 ESRLPRPSKLTNLPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSV 470
            :.|              |:||   .|.:|      |:|.::.|.|.         .|..|..|
Zfish   463 QER--------------FRRR---KKWQG------ERRKESFNKDE---------SEKDSDSP-- 493

  Fly   471 MMSKKYQESVPNCDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQF 535
                   ||:|  |:.:|:..|:...|.|   |:...::::::.|..:|:         .|.|..
Zfish   494 -------ESLP--DSTETQEVAIARENLV---TLMAEQKKIQKQKAGLEQ---------RLAELR 537

  Fly   536 ETHKAKSKQMEEELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNK 600
            |    |::::||.|...:|.::             .|:||                      |..
Zfish   538 E----KARRLEELLPRRVSSEE-------------QREVL----------------------CLL 563

  Fly   601 C----LELERLLPLASASGLDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRL 661
            |    ||:|.....:||...|:|..|     ..:...|.:....|                |..:
Zfish   564 CKVHELEIENAEMQSSALLKDNVIRQ-----KNVVVQRFEQHRHL----------------CHEI 607

  Fly   662 SEQISTAHDDFG-----QLQEKY---------NNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQD 712
            .:|.....||..     .|||.|         .||....:..|..|.|::|.:.....|..
Zfish   608 IQQQRQFIDDHSLLVPPHLQELYEMYMKEMDEKNLDRVVALDKFTIRTLKVHHEGSLPKIT---- 668

  Fly   713 EYRHLELRSDEQCQQLQDENSKLQAEIGTLKERVEEIHSELLEVPNPDTHPED-----MELQNQE 772
                |..|..:..|:|..:    |..:.||.....:..::|.....|...||.     .:..:::
Zfish   669 ----LPSRGRDPLQELDSD----QESVRTLASDNRQGRTKLRRHTLPPILPEPDGERVFKSSHKQ 725

  Fly   773 LKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPE 837
            :|..:....   ..|.:|.:. :.||:.::.: :|||..|...:.:|.|:|...|.        |
Zfish   726 MKNTVVMTP---PPIHINGQG-NRELLPSVLD-EALRCSHLSHSMSSHLDSSPESS--------E 777

  Fly   838 NELDTDLL-QQFTKLSKSIQQIELTDYSGGRRLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQH 901
            |..|..|. ::..::.:.:|.|.:   ...||      ..:...:.:|:|...|:..   |.|:|
Zfish   778 NGTDAPLTPKERQQILRGVQNIAV---KAARR------RSKVLEIDALRLPPPPSPL---DPKKH 830

  Fly   902 DASDSV 907
            .::.|:
Zfish   831 KSNLSL 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	Motor_domain	8..310	CDD:473979	105/334 (31%)
		CCDC158	<505..>729	CDD:464943	43/241 (18%)
		SMC_prok_B	622..1285	CDD:274008	57/306 (19%)
		SMC_prok_B	1110..1875	CDD:274008
kif19	XP_005156460.1	KISc_KIP3_like	11..346	CDD:276821	105/334 (31%)
		EnvC	340..>558	CDD:443969	58/292 (20%)