Protein Alignment cana and kif18a

DIOPT Version :10

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_956533.1
• Gene: kif18a / 393209
• ZFINID: ZDB-GENE-040426-862
• Length: 895
• Species: Danio rerio
• Alignment Length: 852
• Identity: 214/852 - (25%)
• Similarity: 356/852 - (41%)
• Gaps: 225/852 - (26%)

  Fly     7 SSIQVCIKVRPCEPGLTSLWQVKEG---RSIQLADSHA---EP---------------------- 43
            |.::|.::|||...      :.|:|   :.:.:.|:|.   :|
Zfish     8 SHVKVVVRVRPLND------KEKDGNFKKVVHVVDNHMLVFDPKEEEVTFFRGQRVGNRDVRKRA 66

  Fly    44 -----YVFDYVFDEGASNQEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNPGVM 103
                 :|||.||.|.:|..|||:...|.||...:.|.|.|:||||.|.:|||:||:|...:||||
Zfish    67 NKDLKFVFDSVFGEESSQIEVFENTTKAIVDGVLNGYNCTVFAYGATGAGKTHTMLGTSNSPGVM 131

  Fly   104 VLAAKEIFQQIS-SETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIHESG-NGIVNVNCKESIV 166
            .|..||:|.::. .:.::.|.:...|:|:|||:|.|||.... .|.:.|.| ||:|.........
Zfish   132 FLTMKELFARMDLIKEDKVFNVAFSYLEVYNEQIRDLLTNSG-PLAVREDGSNGVVVQGLTLHQP 195

  Fly   167 TSEDDLLRQLYMGNKERVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGS 231
            .|.:.:|..|..||:.|....|:||..||||||:|:|.:..:....|.|..|:.:.:||:|||||
Zfish   196 KSAEHILEALDYGNRNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASLNPNVRVAKMSLIDLAGS 260

  Fly   232 EQV-----------DPADHASSLMIFRNLVKSLSESVDSKPN-SFRDSKLPRIMLPSLGGNVLTS 284
            |:.           :.|:...||:...|::.:|:.....|.: .:|||||.|::..|||||..|.
Zfish   261 ERASATNTKGARLREGANINRSLLALGNVINTLANPKCKKTHIPYRDSKLTRLLKDSLGGNCRTV 325

  Fly   285 IICTITPSFV--EESSSTISFGTCAKKIR--CKPQVCKIDSE----TTMMRQLDRGISMLKDKLA 341
            :|..::||.:  |::.:|:.:...||:|:  .:..|..:||.    ..:..:....|.|||.|
Zfish   326 MIANVSPSSLSYEDTHNTLKYANRAKEIKSTLRSNVMSLDSHIGQYAIICEKQKAEIVMLKQK-- 388

  Fly   342 KKKIKNESQLVLQELEGRIKRDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEE 406
                       |:|.|.|       ...:.:|:...:|||...
Zfish   389 -----------LKEYEER-------KAEAPALNPISIQKRAEF---------------------- 413

  Fly   407 SRLPRPSKLTNLPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVM 471
                  .|::...:.:|..|               .:|:.:::|.    .|||..   ||:....
Zfish   414 ------EKMSESLRSVFSDR---------------LKLRKEHLDI----EKQLNE---SRLTMRH 450

  Fly   472 MSKKYQESVPNCDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLE---MENGKAVN--- 530
            ....:|:|:           .....|:..:.|. |||.::..||...|.|:   ||:.|...
Zfish   451 RESWHQQSL-----------IFFPDNKAERATC-KYERKLASLKSHQEHLQQRLMESEKCFQENE 503

  Fly   531 ------------LGEQFETHKAKSKQME-EELLSSISEKDSTIVSLQQSLEELSRDV-LRNSKED 581
                        ||....|.:...|::: .:|...||:       |||.:|.:|..: :::.:..
Zfish   504 GWLHRIENEMKLLGHDGHTPEELKKELQCHQLQLQISD-------LQQHMEHMSHLISVQDQENT 561

  Fly   582 QMRSMCPELESSCER--ICNKCL----------ELERLLPLASASGLDSVACQFDQLRSE----- 629
            ....:...|.|:|.|  :..|.:          |||||:....|      ....||.::|
Zfish   562 HTHKLVNALLSTCRRQHLALKAMSADGDGSEWEELERLVHRERA------VVWADQEKAEDKRDD 620

  Fly   630 --IAATRMKLESMLSTFSHASCEVSQKTTDC------KRLSEQISTAHD--DFG---QLQEKYNN 681
              |.:|.::   .:.:|||.   ||.::|.|      :|.|:::...|.  |.|   |:.|....
Zfish   621 SGIGSTHLR---PILSFSHL---VSHQSTPCSSEKHTRRTSQRLRPTHSSKDCGPHHQVAEAEGV 679

  Fly   682 LKHKWSSQKLAIDTMQVDYN--TIQQKYLQLQDEYRH-----LELRSDEQ--CQQLQDENSKLQA 737
            || |...:||::...::|.:  .:......|||..|.     |:...:.|  ...:.|.||.:
Zfish   680 LK-KPIRRKLSVSPAKLDGDGPVLSHHPPDLQDVLRQEGMFPLQFTPEGQPHTSSIFDPNSTI-- 741

  Fly   738 EIGTLKE 744
            :||.:::
Zfish   742 DIGHIED 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	Motor_domain	8..310	CDD:473979	113/350 (32%)
		CCDC158	<505..>729	CDD:464943	64/282 (23%)
		SMC_prok_B	622..1285	CDD:274008	36/150 (24%)
		SMC_prok_B	1110..1875	CDD:274008
kif18a	NP_956533.1	KISc_KIP3_like	9..353	CDD:276821	113/350 (32%)
		SMC_N	<345..572	CDD:481474	56/315 (18%)