Protein Alignment cana and Klp31E

DIOPT Version :10

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_609398.2
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Alignment Length: 1348
• Identity: 293/1348 - (21%)
• Similarity: 502/1348 - (37%)
• Gaps: 468/1348 - (34%)

  Fly     2 STKNASSIQVCIKVRPCEPGLTSLWQVKEGRSIQLAD--------SHAEP---------YVFDYV 49
            |....||::|.:::||             ..|.:|.|        :..||         :.||||
  Fly     7 SINKDSSVRVAVRIRP-------------QNSRELIDMCRICTTVTLGEPQIFLGSDKAFTFDYV 58

  Fly    50 FDEGASNQEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTM---------MGDEQNPGVMVL 105
            ||..::..:::....:.:|.:.:.|.|.|:.|||||.|||||||         ..|....|::..
  Fly    59 FDTNSNQCDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESSDSVQLGIIPR 123

  Fly   106 AAKEIFQQI-----SSETER-------DFLLRVGYIEIYNEKIYDLLN--KKNQDLKIHESGNGI 156
            |.:.||..|     ||.:|.       .|.|.|.|||:|||.|:|||:  .||.:.||||..:|.
  Fly   124 AVRHIFSGIEQLEGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDASGQ 188

  Fly   157 VNVNCKESI--VTSEDDLLRQLYMGNKERVVGETNMNERSSRSHAIFRIIIESRK----SDH-SD 214
            :.:: ..||  :....|.|:.|..|...|....|.||::||||||:|.|.:..::    ||: .|
  Fly   189 ITIS-GASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPD 252

  Fly   215 ND-TVKQSVLSLVDLAGSEQVDPADHAS-----------SLMIFRNLVKSLSE-SVDSKPNSFRD 266
            || ....|....|||||||::.......           .|:...|.:.:|.: |..:....:||
  Fly   253 NDLETLTSKFHFVDLAGSERLKRTQATGERAREGISINCGLLALGNCISALGDKSKRALHVPYRD 317

  Fly   267 SKLPRIMLPSLGGNVLTSIICTITPS---FVEESSSTISFGTCAKKIRCKPQVCKIDSETTMMRQ 328
            |||.|::..|||||..|.:|..::||   |: |:.:|:.:...|:.|:.|.::.: |..:..:.|
  Fly   318 SKLTRLLQDSLGGNSQTLMIACVSPSDRDFM-ETLNTLKYANRARNIKNKVKINQ-DQSSRTISQ 380

  Fly   329 LDRGISMLKDKLAKKK----------------IKNESQLVLQELEGRIKRDMLKIVSS-ASLD-- 374
            |.|.|:.|:.:|.:.|                ..||::|:|.|:: |:::.:..:.|: |:|.
  Fly   381 LRREIAALQLELLEYKQGKLIVDCEGNTTISDTFNENKLLLSEIK-RLQQRLKSLQSTIATLTQR 444

  Fly   375 --DYRLQKRRRTWTLTASGSEGDAPVLA------------LPEPEESRLPRPSKLTNLP---KPL 422
              |.:.......||...:.....|.|:.            |.|.||.|.....|.|..|   ||:
  Fly   445 NADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTKLIESEEHRKQMEIKATTSPRNAKPV 509

  Fly   423 FQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQESVP-----N 482
            :. ..|..|||                       |.|.||.     .::||:    |:|     |
  Fly   510 YD-SDIITKAK-----------------------KDLERER-----ELLMSR----SLPGIQNQN 541

  Fly   483 CDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQMEE 547
            ..:.:||:::..:..:...:.:|..:..::...:.||:||:.|.:.    ||..||       .|
  Fly   542 VSSEETEVASSDSEAEEVVKDLEAIDNDIEMRTKLIEQLELTNSRY----EQMRTH-------YE 595

  Fly   548 ELLSSI--------SEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLEL 604
            |.||.:        .|:|..:.::..|:...|:|.|:..|.| ..|....:::...::.|
  Fly   596 EKLSVLYCKIENTQKERDDVLANMTTSVSTPSKDSLKKVKTD-YESKISHMQTEIRKLQN----- 654

  Fly   605 ERLLPLASASGLDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQISTAH 669
                            .|.:.:||:                                 :|:.:..
  Fly   655 ----------------AQREHIRSK---------------------------------QQLKSHE 670

  Fly   670 DDFGQLQEKYNNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRSDEQCQQLQDENSK 734
            ...|.|:.:.|.|  |::..||            .:|..|..:.::..|.|..::..||..|..:
  Fly   671 VRIGTLRNELNEL--KFAKVKL------------MKKMSQQSNRHKQEESRKSKEIAQLLKEQRR 721

  Fly   735 LQAEIGTLKERVEEIHSELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELM 799
            .:..:.||:.:|                    ..:.|.||::
  Fly   722 QKNAVLTLEAKV--------------------SAKEQILKRK----------------------- 743

  Fly   800 STIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDYS 864
              .:|..|||:..:.::
  Fly   744 --TEEVIALRKSQRGKS------------------------------------------------ 758

  Fly   865 GGRRLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGF-LKCQRFQIVKINQEQN 928
             |:|                    .||         |..|....|.|| .:..|      ::.:|
  Fly   759 -GQR--------------------APA---------HLTSKIATLDGFSTRSAR------HRWEN 787

  Fly   929 L---VKEEDRMRDIIFQLKQEVDGKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILCEE 990
            |   :....|.|.:|.||::|::   .||.|.::                           |..|
  Fly   788 LYRNILHAARNRQLITQLEKELE---RLILERED---------------------------LSRE 822

  Fly   991 LQTKDTVQTANKQ--ESQEVLTLKTSLAHLKSKVCELQKKLEK--------QSEDEKISELQSDI 1045
            |...:..|||::|  |..||..|||::::::..:..:|:.:.:        ||...||..|..::
  Fly   823 LNIMENGQTADRQTDEFNEVDNLKTNISYIQENIEHVQQAIMEFEDTKDTVQSHVNKIQSLLDEV 887

  Fly  1046 GEISEC------------CLSMELKLADIVNWQAEELRPLDQLQESGVE---LQH--------HS 1087
            ..::|.            .:|..|.:|: .:.|.:|....:..||||::   |||        |.
  Fly   888 STVAEAKFILQKFSDTAIVMSCNLAIAE-SHLQEKESLLKEVKQESGIQQQILQHFLSQNSNVHI 951

  Fly  1088 TTAEESL-----NVEKPIQEQTERTLTTEYERRIEQLEESLQRAQEELSILEKRKTDENKSLQLE 1147
            ....:||     |:...:...::::|.:.....|.|.:::.:..|.|:    :|.|..:.|
  Fly   952 ADIFDSLNLKGSNIASSVNPGSQKSLISNATYDIPQDDKNSEFHQVEM----RRTTSRSPS---- 1008

  Fly  1148 YMAKIETSENENRS-KFRAYCLDLKETQKRYE------EQLQQTNEKL 1188
               .:..|:..::| |.|      :.|.||.:      |..:||..|:
  Fly  1009 ---PLGNSDPFDKSPKVR------RRTAKRQDLLFGDTELSEQTFNKM 1047

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	Motor_domain	8..310	CDD:473979	114/364 (31%)
		CCDC158	<505..>729	CDD:464943	40/231 (17%)
		SMC_prok_B	622..1285	CDD:274008	104/616 (17%)
		SMC_prok_B	1110..1875	CDD:274008	18/86 (21%)
Klp31E	NP_609398.2	KISc_KIF4	12..364	CDD:276823	115/366 (31%)
		Mplasa_alph_rch	<372..>748	CDD:275316	96/534 (18%)
		SMC_prok_B	622..>899	CDD:274008	77/504 (15%)
		Rcc_KIF21	798..870	CDD:410202	22/101 (22%)