Protein Alignment cana and Kif6

DIOPT Version :9

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_796026.2
• Gene: Kif6 / 319991
• MGIID: 1098238
• Length: 802
• Species: Mus musculus
• Alignment Length: 963
• Identity: 218/963 - (22%)
• Similarity: 389/963 - (40%)
• Gaps: 285/963 - (29%)

  Fly     8 SIQVCIKVRPC----EPGLTSLWQ-VKEGRSIQ------LAD----SHAEPYVFDY--VFDEGAS 55
            :||:..:|:|.    :.|:.|:.: .|...|::      |||    :..|.|.|.:  :||:.|.
Mouse     5 TIQIFARVKPTVRKQQQGIYSIDEDEKLTHSLEIVLPRDLADGFVNNKRESYKFKFQRIFDQEAK 69

  Fly    56 NQEVFDRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQ---NPGVMVLAAKEIFQQISSE 117
            .:.:|:.:||.:..:.:.|.||||||||||.||||:|:.|..:   :.|::......||:|:..:
Mouse    70 QEIIFEIIAKPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIFEQLQKD 134

  Fly   118 TERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIV------NVNCKESIV---TSEDDLL 173
            :.:.:...:.|:|||||..||||:.:::..|:.:.....:      |::.|...:   |:|::.|
Mouse   135 SSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPDQNIHLKNLSLHQATTEEEAL 199

  Fly   174 RQLYMGNKERVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQVDPAD 238
            ..|::|:..|::.||.||:.|:|||.||.:.:.|::...:   ||:.:.|.||||||||:|....
Mouse   200 NLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEPGSA---TVRHAKLHLVDLAGSERVSKTG 261

  Fly   239 HAS-----------SLMIFRNLVKSLSESVDSKPNS---FRDSKLPRIMLPSLGGNVLTSIICTI 289
            ...           ||.....::.:|||    |..:   :|:|.:..::..|||||.:|::|.|:
Mouse   262 VGGLLLTEAKYINLSLHYLEQVIIALSE----KHRTHIPYRNSMMTSVLRDSLGGNCMTTMIATL 322

  Fly   290 T--PSFVEESSSTISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNESQLV 352
            :  ...::||.||..|   |:::..                                ||||: ::
Mouse   323 SLEKRNIDESISTCRF---AQRVAL--------------------------------IKNEA-IL 351

  Fly   353 LQELEGRIKRDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTN 417
            .:|::.|     |.||        ||||.........:.:.|:....||.|.|..:|
Mouse   352 NEEIDPR-----LMIV--------RLQKEIEDLKAELAMATGEQRTEALTEAELLQL-------- 395

  Fly   418 LPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETAS------RIPSVMMSKKY 476
                                   ||.:.:...|..|....::|.:...      ....::..||.
Mouse   396 -----------------------EKLIASYLEDQDPESRLEVGADMRKIHHCFHHFKKLLNDKKT 437

  Fly   477 QESVPNCDAPQTEISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAK 541
            .|:..:.:          ::.|..:|.:.  :|:..:|...:::.:.|....||:      .|.:
Mouse   438 LENTVSSE----------STRQACQEPLR--DEEYTKLLGLLKQRDNEINILVNM------LKKE 484

  Fly   542 SKQMEEELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLELER 606
            .|:.::.|.:|..||..|                |..:.....:..|.:..:
Mouse   485 KKKTQDALQNSSLEKSDT----------------RPPQNSPFIAGSPAVPRT------------- 520

  Fly   607 LLPLASASG--LDSVACQFDQ--------LRSEIAATRMKLESMLSTFSHASC--------EVSQ 653
              |.:||..  .|...|:...        :|.|::..|.:...:... .||..        .:.|
Mouse   521 --PFSSAPSHTQDLSICRHRSSLLHKKTGMREEMSLGRQEAFEIFKR-DHADSVTIEDNKQVLKQ 582

  Fly   654 KTTDCKRLSEQISTAHDDFGQLQEKYNNLKHKWSSQKLAIDTMQVDYNTI-------QQKYL--Q 709
            :.::.|.|.|.|:.|....|||::..|. :|   .|::|:.   :..||:       |::.|  |
Mouse   583 RFSEAKALGESINEARSKIGQLKDAINQ-RH---LQQVALG---ISENTVPASTPDPQEEKLRAQ 640

  Fly   710 LQDE---YR--------------HLELRSDEQCQQLQDENSKLQAEIGTLKERVEEIHSELLEVP 757
            |::|   |:              ||:|..|:...:||.|.....||..|           .|:|.
Mouse   641 LEEEKGRYKTAFMHLKALKVEIEHLQLLMDKAKVKLQKEFEAWWAEEAT-----------SLQVN 694

  Fly   758 NPDTHPED------MELQNQELKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALREEHKQRT 816
            :|.|:.:|      .:.|.|.|.|:.|:        .|..|..:..|    :.||    .:.:|.
Mouse   695 SPATNLQDAVKPFPQQDQAQLLSKKSSR--------DLEVENGAGRL----EVCD----RNARRI 743

  Fly   817 TNS---DLESMKSSGVGTECSD---------PENELDTDLLQQFTKLSKSIQQ 857
            ..|   :.:|.:.||......|         .:::.|:|:| .|.|..:||.|
Mouse   744 LPSPCPNQQSQEPSGSRVLVQDRPLSSIPLTGDSQTDSDIL-AFIKARQSILQ 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	105/352 (30%)
		Motor_domain	8..310	CDD:277568	105/346 (30%)
		SMC_prok_B	<471..1270	CDD:274008	89/449 (20%)
		Mplasa_alph_rch	924..1647	CDD:275316
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171
Kif6	NP_796026.2	KISc_KIF9_like	5..343	CDD:276826	105/347 (30%)
		Kinesin	11..345	CDD:278646	103/375 (27%)
		Cob_adeno_trans	<350..>408	CDD:294596	18/101 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900