Protein Alignment cana and Klp3A

DIOPT Version :9

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_001284830.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Alignment Length: 1582
• Identity: 333/1582 - (21%)
• Similarity: 570/1582 - (36%)
• Gaps: 512/1582 - (32%)

  Fly     1 MSTKNASSIQVCIKVRP-CEPGLTSLWQVKEGRSI----QLADSHAEPYVFDYVFDEGASNQEVF 60
            ||:::.|.:.|.::||| .:..|....::...||.    |:..:..|.|.::||||...|.:::|
  Fly     1 MSSEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLF 65

  Fly    61 DRMAKHIVHACMQGSNGTIFAYGQTSSGKTYTMMGD------EQNPGVMVLAAKEIFQQISS-ET 118
            :...:..|...:.|.|.||.|||||.|||||| ||.      :.:.||:..|..:||..|:. ::
  Fly    66 ETCVQAKVKKLLNGYNVTILAYGQTGSGKTYT-MGTAFNGVLDDHVGVIPRAVHDIFTAIAEMQS 129

  Fly   119 ERDFLLRVGYIEIYNEKIYDLLNKKNQD---LKIHESGNGIVNVNCKESIVTSEDDLLRQLYMGN 180
            |..|.:...::|:|.|:.|||.:.|.:|   :.|.|..|.|:.....|.:|||...:...|..|:
  Fly   130 EFRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRIIMPGLTELVVTSAQQVTDHLIRGS 194

  Fly   181 KERVVGETNMNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQV----------- 234
            ..|.|..|.|||.||||||||.:.:.:.|.|  ...:|..|..:||||||||:.
  Fly   195 AGRAVAATAMNETSSRSHAIFTLTLVATKLD--GKQSVTTSRFNLVDLAGSERCSKTLASGDRFK 257

  Fly   235 DPADHASSLMIFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITPS--FVEES 297
            :..:....|:...|::.:|.....:....:|.|||.|::..|||||.:|.:|..::|:  .|.|:
  Fly   258 EGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAET 322

  Fly   298 SSTISFGTCAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNESQLVLQELEGRIKR 362
            .||:.:...|.:|:.|| |..:|....       .::||||.:.|.:::..|       .|::..
  Fly   323 LSTLRYADRALQIKNKP-VVNLDPHAA-------EVNMLKDVIQKLRVELLS-------GGKMSS 372

  Fly   363 DMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTNLPKPLFQRRG 427
            .::..|.:|.|.                         |:|
  Fly   373 SLISAVGAAGLG-------------------------AIP------------------------- 387

  Fly   428 IAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQESVPNCDAPQTEISA 492
                                                                   |:      .:
  Fly   388 -------------------------------------------------------CE------ES 391

  Fly   493 LTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQMEEELLSSISEKD 557
            |..|...|.| |::.:|||:.|::...:|:.|
  Fly   392 LAGSMANAAE-IQRLKEQVRTLQDRNRKLQQE--------------------------------- 422

  Fly   558 STIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLELERLLPLASASGLDSVACQ 622
                 |.|||.:|:        |.:||:...|.                               .
  Fly   423 -----LHQSLLDLT--------EKEMRAHIAEQ-------------------------------A 443

  Fly   623 FDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQISTAHDDFGQLQEKYNNLKHKWS 687
            .|:|||.::..:.||:.                      .||.     .||  .|..|.
  Fly   444 HDKLRSHVSELKNKLDQ----------------------REQA-----QFG--NENTNG------ 473

  Fly   688 SQKLAIDTMQVDYN-TIQQKYLQLQDEYRHLELRSDEQCQQLQDENSKLQAEIGTLKERVEEIHS 751
                  |....|:: .:.:.:::||.....||.:..|..|:|...:.....|.|.     :|:|
  Fly   474 ------DNEMRDFSLLVNRVHVELQRTQEELESQGHESRQRLSSRSHTEGGESGG-----DEVH- 526

  Fly   752 ELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALREEHKQRT 816
            |:|.     :|.|                  |:...|:|:   :.||.:..::.|..:|.|::..
  Fly   527 EMLH-----SHSE------------------EYTNKQMNF---AGELRNINRQLDLKQELHERIM 565

  Fly   817 TN-----SDLESMKSSGVGTECSDPENELDTDLLQQFTKL-SKSIQQIELTDYSGGRRLFIYNHA 875
            .|     ||.|.:|......:..|.|.| ..||:.|...: ||.|
  Fly   566 RNFSRLDSDDEDVKLRLCNQKIDDLEAE-RRDLMDQLRNIKSKDI-------------------- 609

  Fly   876 EQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVKINQEQNLVKEEDRMRDII 940
                   |.||..|..|.|:  ..:.:.||         .:|    |:..:.||:|..|:.|:.|
  Fly   610 -------SAKLAEERRKRLQ--LLEQEISD---------LRR----KLITQANLLKIRDKEREKI 652

  Fly   941 FQLKQEVDGKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILCEELQTKDTVQTANKQES 1005
            ..|..|:   :.:.|.:.::|..:|.:.....|.:.::.:.      ..:|::||     .|.:|
  Fly   653 QNLSTEI---RTMKESKVKLIRAMRGESEKFRQWKMVREKE------LTQLKSKD-----RKMQS 703

  Fly  1006 QEV--LTLKTSLAHLKSKVCE--------LQKKLEKQSEDEKISELQSDIGEISECCLSMELKLA 1060
            :.|  .||.:....:..:.||        |:..||:|:..:.......|.|..:....:...|..
  Fly   704 EIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAAGSSNANAKTD 768

  Fly  1061 DIVNWQAEEL----------RPLDQLQESGVELQHHSTTAEESLNVEKPIQEQT-ERTLTTEYER 1114
               :|...||          ..|:||.|....:.:|....:         ||:| :.....|..|
  Fly   769 ---SWVDRELEIILSLIDAEHSLEQLMEDRAVINNHYHLLQ---------QEKTSDPAEAAEQAR 821

  Fly  1115 RIEQLEESLQRAQEELSILEKRKTDENKSLQLEYMAKIETSENENRSKFRAYCLDLKETQKRYEE 1179
            .:..|||.|:....::|.|:::....:...::..:|:...|..|:|:..:.....|.:.::....
  Fly   822 ILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQQRRLQAS 886

  Fly  1180 QLQQ---TNEKLASVTTQCQVHLDVIKRSLQEKITQAEKERNELAVRHKAELEKIRETLKEKESS 1241
            .|.:   |.::|.:.....|...|...:.|  ::.|::.|...|| :.:|..||:...::.....
  Fly   887 SLNEQRTTLDELRAQLLDAQQQEDAASKRL--RLLQSQHEEQMLA-QQRAYEEKVSVLIRTANQR 948

  Fly  1242 YKEKLRQAEEERDKEISRLEVMRNTIAELHKTNSDREVELEGVKMEKCQLKKLYDKSMLELEQLQ 1306
            :.|....||:::          ||.|  |.:..|.||...:                  ||::|:
  Fly   949 WAEARSPAEDQQ----------RNQI--LEELLSSREALQQ------------------ELDKLR 983

  Fly  1307 CTADQKSSDLLPGSSNENIDDLQKKCDQYVQDLELLRGEKAELLSEI-------------QKING 1358
              |..||......|..:::||          ..:::.|.:..:||::             ::|..
  Fly   984 --AKNKSKSKAVKSEPQDLDD----------SFQIVDGNETVVLSDVSDDPDWVPSTSKSKRIQS 1036

  Fly  1359 QHSNTIKKLEEIEAEMITLTTQKELERCEIAEKLETFKSKEA--DIKEALHCAQLRLHAYDKLVC 1421
            ...|.|...|:.:|.:.:|..          ..:::..|..|  |.|....|.       .:..|
  Fly  1037 DSRNVISPPEKQDANVTSLGN----------SSIQSLNSTSATEDGKRCKGCK-------CRTKC 1084

  Fly  1422 EYERLKGCLSDSNKLSE------------NLQKKVERLHAEQLALQEGISGRDSEIKQLRSELKD 1474
            ..:|. ||||.:|..||            ||:.     ||.|..  :| .|:..|.:.......|
  Fly  1085 TTKRC-GCLSGNNACSETCVCKSNCRNPLNLKD-----HASQCG--DG-DGQKDETEDADKSDDD 1140

  Fly  1475 AIDENKTVREAKVGLENSLKAV 1496
            ..||.:|.:      ||::|.|
  Fly  1141 GDDEPQTSK------ENAVKFV 1156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	110/335 (33%)
		Motor_domain	8..310	CDD:277568	107/329 (33%)
		SMC_prok_B	<471..1270	CDD:274008	154/829 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316	124/624 (20%)
		CENP-H	1204..>1266	CDD:283493	12/61 (20%)
		CALCOCO1	<1489..1850	CDD:285171	4/8 (50%)
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	108/331 (33%)
		Kinesin	14..335	CDD:278646	106/323 (33%)
		Smc	<396..>994	CDD:224117	161/852 (19%)
		FlaC	522..633	CDD:225888	36/181 (20%)
		TCR	1075..1110	CDD:281618	10/42 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930