Protein Alignment cana and golg-4

DIOPT Version :9

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_001355507.1
• Gene: golg-4 / 175445
• WormBaseID: WBGene00010306
• Length: 1642
• Species: Caenorhabditis elegans
• Alignment Length: 1791
• Identity: 353/1791 - (19%)
• Similarity: 742/1791 - (41%)
• Gaps: 403/1791 - (22%)

  Fly   336 LKDKLAKK--KIKNESQLVLQELEGRIKRDMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPV 398
            ||::|..:  |:|..:|...::|             :|.:..||.....:     .:||:..|.:
 Worm     5 LKNRLDNEAGKLKQSAQQYGEQL-------------AAQVGQYRQAMNEQ-----PAGSDASASI 51

  Fly   399 LA--LPEPEESRLPRPSK---------LTNLPKPLFQRRGIAPKAKGICKTLKEKRLQTDNMDTM 452
            ..  ..|..|::...|:.         ::.:|:......|::.     .::...:|.::.:.|::
 Worm    52 SKRFTGESGETKAENPANTSIESSSAIMSEIPEADLLGLGLSS-----TESPSNRRRRSPSEDSI 111

  Fly   453 PGRAKQLGRETASRIPSVMMSKKYQESVPNCDAPQTEISALT-------ASNQVAKETI----EK 506
            ......|.....| ||:.:.|.  .|::|: |:......|.:       |.|...|:.:    .|
 Worm   112 HSNESTLAALLQS-IPNAISSA--LETIPS-DSESVASDAFSVRSTNDPAYNSRLKQRLATYKAK 172

  Fly   507 YEEQV-------------KRLKET--------IERLEME---------------NGKAVNLGEQF 535
            |.:.|             ::|.||        :|:|.:|               :||. .|.::.
 Worm   173 YRDAVHRHNKLVDDVNTTRKLLETTQDECLQKVEKLRLEKRILAEKLSNSAGNGDGKE-ELEKKC 236

  Fly   536 ETHKAKSKQMEEELLSSISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNK 600
            |.:|...:|.:.::.|...:|..     ||.|..:..|   :|.:.::|.|...::.:.|...|:
 Worm   237 EDYKRMLEQCKIKIKSLQQDKKE-----QQQLITVDND---DSVDPRIREMEQRIQKTEEEWTNR 293

  Fly   601 CLELERLLPLASASGLDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQI 665
            ..|.::                  |....:|.|:.::.:.|   .:...|:.|....|..|.:|.
 Worm   294 INESDQ------------------QHAINLATTKAEMHAAL---ENKDSEIEQWRRKCATLEQQD 337

  Fly   666 STAHDDFGQLQEKYNNLKHKWSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRSD--EQCQQL 728
            :.|:..:....||...:.....|:|..:.....:......|.:..::|.:..|:.:|  ::.::|
 Worm   338 ADANQRWSDKVEKVQAMNKALESEKNEMIEKLSEAKAQGVKAVLEEEERKRTEMETDLNDEIERL 402

  Fly   729 QDENSKLQAEIGTLKERVEEIHSELLEVPNPDTHPEDMELQ-----NQELKKRLSKLQWEFDEIQ 788
            ::|..|::.|:.|.|.::|...|...:....|.....:||.     ..:|:.|:::....|:
 Worm   403 KEETEKMRLEMSTYKVQLEAKESREFDEEREDVEALKLELNAVKSTRDDLESRITENSSSFE--- 464

  Fly   789 LNYECLSNELMST--------IQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLL 845
             ||...:.:.::.        :.|||..||::::|...|  |.:.:....|:      |.|...:
 Worm   465 -NYRSEAEKTLAAAKAQFEKMVSECDKWREKYEERAAAS--EHIATVEFETQ------ETDAHRI 520

  Fly   846 QQFTKLSKSIQQ--IELTDYSGGRRLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVF 908
            .:|....|::.:  .|||        ..:..|:::::....:|.....:.||
 Worm   521 LEFEAEKKALAEKCEELT--------LKFEQADKEKNEMVQQLSRLQQEMLE------------- 564

  Fly   909 LKGFLKCQRFQIVKINQEQNLVKEEDRMRDIIFQLKQEVDGK----KNLIEEEKEVINNLRAQIT 969
                 ||...| .::|:.:.|.:|.....|.:.|..:.:.|:    |.::|.||:...|.:.|..
 Worm   565 -----KCDALQ-AEVNEAKALREEIQAKYDDVTQKAERIQGELEESKKVLESEKQAFENEKEQER 623

  Fly   970 SLNQIETIKNQNAKTKILCEELQTKDTVQTANKQESQEVLTLKTSLAHLKSKVCELQK-----KL 1029
            .....:.::..|::..||       |.|....:|..:|||..:.::..|..|:.|.:|     |.
 Worm   624 EEQLAKAMEKLNSEQNIL-------DEVTKKLEQSEEEVLAARGAIQELTEKLEESEKETSTAKT 681

  Fly  1030 EKQSEDEKISELQSDIGEISECCLSMELKLADIVNWQAEELRPLDQ-LQE-----SGVELQH--- 1085
            |.::..:|:...::.:.|.|:...:|:::|.:....:.|.:..|.| |:|     |.||:|.
 Worm   682 ELEAVSKKLDSSETSLKEFSDMIEAMKIQLINCEKQKDEAVELLKQKLEEVEKNMSDVEVQKQLL 746

  Fly  1086 -HSTT------AEESLNVEKPIQE------------QTERTLTTEYE----RRIEQLEESLQRAQ 1127
             .|||      ||.:..|:|.::|            :.||.|.|..|    ..|.::.:.::.|:
 Worm   747 LESTTSEMKQHAEAAEIVKKQLEEAQSSIENLKKDAENERNLKTALESDESSAISEITKQMEAAK 811

  Fly  1128 EELSILEKRKTD---------------------ENKSLQLEYMAKI-ETSENEN--RSKFRAYCL 1168
            :||...||.|::                     ..|:.:|| |||| :::|:|.  |.:......
 Worm   812 KELEASEKEKSELREQMDRLQKVHNAGQEDIQKLQKTWELE-MAKIAKSTEDEKLAREQLAGELE 875

  Fly  1169 DLKETQKRYEEQLQQTNEKLASVTTQCQVHLDVIKRSLQEKITQAEKERNELAVRHKAELEKIRE 1233
            :.||..|..||:.....::........:..:.|:|..| |:...|.:...|||...||  :||:|
 Worm   876 NAKEDLKVVEEEKHTGIQRAQGALDDAEKEVKVLKEQL-ERAQSALESSQELASSQKA--DKIQE 937

  Fly  1234 TLKEKESSYKEKLRQAEEERDKEISRLEVMRNTIAELHKTNSDREV---ELEGVKMEKCQLKKLY 1295
            ..||.:::.|....:.|...       |::|:..|.|..:||:.|:   :||.:..| .|.::..
 Worm   938 LEKELQNAQKRSSEELETAN-------EMVRSLTATLENSNSETEILKQKLETLDKE-LQARQQT 994

  Fly  1296 DKSML-ELEQLQCTADQKSSDLLPGSSNENIDDLQKKCDQYVQDLELLRGEKAELLSEIQKINGQ 1359
            :|::. |:..|..:..:|.      .....|.:||.:    :..:|:.:.||.||:....:...|
 Worm   995 EKALTEEINVLTTSLAEKE------QQTAQIQNLQTQ----IYQMEVEKEEKVELVKVQLQQAAQ 1049

  Fly  1360 HSNTIK-----KLEEIEAEMITLTTQKELERCEIAEKLETFKSKEADIKEALHCAQLRLHAYDKL 1419
            .|::.:     ::|::||::      |.:|:.: ||.|.:..:::..::..||  ||.:...:||
 Worm  1050 SSSSAEEALRAEIEQLEAKL------KAVEQAK-AEALNSLLAEKEHLQAQLH--QLGVEKEEKL 1105

  Fly  1420 VCEYERLKGCLSDSNKLSENLQKKVERLHA--------EQLALQEGISGRD---SEIKQLRSELK 1473
            .....:|:.....|:.:.:.|:.::|:|.|        ::.||...::.::   ::|::|:::|.
 Worm  1106 EMVKVQLQQAAQSSSSVEQALRAEIEKLEAKLQEIEEEKKNALNASLAEKEQQTAQIQELQAQLH 1170

  Fly  1474 D-AIDENKTVREAKVGLENSLKAVQENMSAQEGQFKQKIADIKGSVDELQIKLKSLQEVRDHLES 1537
            . .:::.:.:...||.|:   :|.|.:.|.::.        ::..:::|:.||:.:::.:....|
 Worm  1171 QLEVEKEEKLEMVKVQLQ---QAAQSSSSVEQA--------LRAEIEKLEAKLQEIEKAKMQNSS 1224

  Fly  1538 RNEELKRKLKDAQELQNM--VDKERKLNSSLREDFDKL-----------EQTKLDLEE-QLRAKK 1588
            :.|:..|:|.:..|...:  :.|| |:.|.||.:...:           |:||:|..| :.|.|:
 Worm  1225 KREQKVRELSNLNEKMRVEFIAKE-KIISDLRSELSTISTELVVQKATVEKTKMDFGELETREKR 1288

  Fly  1589 VEIDRRSKELGEV------TKDCENIRSDLEAQTNDFLKERETLNLTISDLRLHNEQLLETSKNY 1647
            ...||.::::.|:      .|:.|.:.|.||.:...:.:.:.:....|:.|....|:.|:.::|.
 Worm  1289 ATADRENEKMEEIRLRETFAKELETMGSALEVKETAYNELKASAEKKIAKLTSQFEEKLKKAQNS 1353

  Fly  1648 LSDIT---------AANNLNLEMKKNLHDLTKECKSLRSDLQS---KE-------EYFQTQKQLL 1693
            ..:.:         :|....||.::.|..|.:..||..|:::.   ||       .:::.:|::|
 Worm  1354 QDEASESRFKTLEASAEQAKLESEQKLRALEELLKSSESEIEELKIKEISAEKDRSHWEVEKEML 1418

  Fly  1694 DETISNLKEENRKME---EKLSSGN--KALKEDCEKLRSTLESKELILQQNKQELEERLTVINEK 1753
            :.....|.:....:|   :||::.|  ||:|.|.:..:        ::::.::|:::....:|:|
 Worm  1419 EGEAKELTDRIEGLEAEVKKLTAANETKAVKADTDARK--------VVRELQKEVKQLYNELNDK 1475

  Fly  1754 NGKNALLDAQLKSNETAFTSLRKAWIKQSLAIEAANKRS--------LEMEQKVDKRTREYEELR 1810
            |.:..::..:|...:|:..:.....::....::..::||        ..::||:|....|.::||
 Worm  1476 NQQFDMVQEELTRLKTSKETAENGQLQVQKQMDEEDRRSEFSFKEEIASLKQKLDASLTEADDLR 1540

  Fly  1811 STLKTREINFRSEKERMDGTISSL----------LEDKRNLEEKLCTVTELLAK----------- 1854
            ..:...|...||......|...|:          .|..||:..:..|..|.|.|
 Worm  1541 MQVSRNEKTPRSNGNASTGRTKSMELHGIADPAEAEYLRNVLYRYMTNRESLGKESVTLARVIGT 1605

  Fly  1855 --------LKRELPALHTQKVN-----GGDVSIELN 1877
                    :|..:.:..:::.:     ||.||..||
 Worm  1606 VARFDESQMKNVISSEESRQASWAAAVGGTVSHALN 1641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526
		Motor_domain	8..310	CDD:277568
		SMC_prok_B	<471..1270	CDD:274008	188/927 (20%)
		Mplasa_alph_rch	924..1647	CDD:275316	182/828 (22%)
		CENP-H	1204..>1266	CDD:283493	17/61 (28%)
		CALCOCO1	<1489..1850	CDD:285171	82/422 (19%)
golg-4	NP_001355507.1	DUF3584	207..>884	CDD:378817	151/753 (20%)
		SMC_prok_B	577..1442	CDD:274008	198/914 (22%)
		SH3_and_anchor	<1444..1549	CDD:275056	19/112 (17%)
		Grip	1572..1620	CDD:197860	8/47 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000