Protein Alignment cana and kif5b

DIOPT Version :9

• Sequence 1: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Sequence 2: NP_001122126.1
• Gene: kif5b / 100038146
• XenbaseID: XB-GENE-854737
• Length: 962
• Species: Xenopus tropicalis
• Alignment Length: 1167
• Identity: 292/1167 - (25%)
• Similarity: 477/1167 - (40%)
• Gaps: 326/1167 - (27%)

  Fly     8 SIQVCIKVRPCEPGLTSLWQVKEG----RSIQLADS---HAEPYVFDYVFDEGASNQEVFDRMAK 65
            ||:|..:.||....     :|..|    ...|..|:   .::|||||.||....|.::|::..||
 Frog     8 SIKVMCRFRPLNDS-----EVTRGDKYVAKFQGEDTVVMASKPYVFDRVFQSNTSQEQVYNACAK 67

  Fly    66 HIVHACMQGSNGTIFAYGQTSSGKTYTMMGDEQNP---GVMVLAAKEIFQQISSETER-DFLLRV 126
            .||...:.|.|||||||||||||||:||.|...:|   |::....::||..|.|..|. :|.::|
 Frog    68 AIVKDVLDGYNGTIFAYGQTSSGKTHTMEGKLHDPDGMGIIPRIVQDIFNYIYSMDENLEFHIKV 132

  Fly   127 GYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNV-NCKESIVTSEDDLLRQLYMGNKERVVGETNM 190
            .|.|||.:||.|||:....:|.:||..|.:..| .|.|..|.|.|:::..:..|...|.|..|||
 Frog   133 SYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNM 197

  Fly   191 NERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQVDPA-------DHA----SSLM 244
            ||.|||||:||.|.:   |.:::..:......|.||||||||:|...       |.|    .||.
 Frog   198 NEHSSRSHSIFLINV---KQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLS 259

  Fly   245 IFRNLVKSLSESVDSKPNSFRDSKLPRIMLPSLGGNVLTSIICTITPSFVE--ESSSTISFGTCA 307
            ...|::.:|:|.....|  :||||:.||:..|||||..|:|:...:||...  ||.||:.||..|
 Frog   260 SLGNVISALAEGSVYIP--YRDSKMTRILQDSLGGNCRTTIVICCSPSAYNEAESKSTLLFGQRA 322

  Fly   308 KKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNES-QLVLQELEGRIKR--------- 362
            |.|  |..|| ::.|.|        ....|.|..|:|.|.:| :..:|.||..:.|
 Frog   323 KTI--KNTVC-VNVELT--------AEQWKKKYEKEKEKTKSLRSTVQWLENELNRWRKGETVPI 376

  Fly   363 ----DMLKIVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTNLPKPLF 423
                |..|....|.:.|..:...:...||.|:.::.:            |.....::|.|.|.|.
 Frog   377 EEQYDKEKANMDAFVVDNFVNNEKPAVTLAANFTDAE------------RRKCEEEVTKLYKQLD 429

  Fly   424 QRRGIAPKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQESVPNCDAPQT 488
            .:.....:...:.:.||::.|..:.:                    :..:::.|:::      |.
 Frog   430 DKDEEINQQSQLVEKLKQQMLDQEEL--------------------LASTRRDQDNM------QA 468

  Fly   489 EISALTASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQMEEELLS-S 552
            |::.|.|.|..:|       |:||.:.:.:|.|      |||..::.:..:.|||  |.::|| .
 Frog   469 ELNRLQAENDASK-------EEVKEVLQALEEL------AVNYDQKSQEVEDKSK--EYDILSEE 518

  Fly   553 ISEKDSTIVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLELERLLPLASASG-- 615
            :::|...:.|:...|::|..  :.|.::.:...|...|             |:.|..:..|.|
 Frog   519 LNQKSVILSSIDSELQKLKE--MTNHQKKRATEMMTSL-------------LKDLAEIGIAVGGN 568

  Fly   616 ---LDSVACQFDQLRSEIAATRMKLESMLSTFSHASCEVSQKTTDCKRLSEQISTAHDDFGQLQE 677
               ...|:...|:   |....|:.:..|.|       ||......||:|.          |...|
 Frog   569 DGKQPEVSGMIDE---EFTVARLYISKMKS-------EVKTMVKRCKQLE----------GTQSE 613

  Fly   678 KYNNLKHKWSSQKLAIDTMQVDYNTIQQK----YLQ-LQDEYRHLELRSDEQCQQLQDENSKLQA 737
              :|.|.:.:.::||...:::..:..:.|    |:| ::.:.||||    |....|.:|..||:|
 Frog   614 --SNKKMEENEKELAACQLRISQHEAKIKSLTEYVQNVEQKKRHLE----ESVDSLNEELVKLRA 672

  Fly   738 EIGTLKERVEEIHSELLEVPNPDT---HPEDMELQN--QELKKRLSKLQWEFDEIQLNYEC---L 794
            :     |:|.|:..|.|......|   |..:.::|:  :..:|:||.|:   |||:...:.   |
 Frog   673 Q-----EKVHEMEKEHLNKVQTATEVKHAVEEQIQSHRETHQKQLSALR---DEIETKEKVITEL 729

  Fly   795 SNELMSTIQECDALREEHKQRTTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIE 859
            .::....:.|.:.||.||         |.:|
 Frog   730 QDQNQKMVLEQERLRVEH---------EKLK---------------------------------- 751

  Fly   860 LTDYSGGRRLFIYNHAEQDQSVPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVKIN 924
                          :|:|::|                 .|.|:
 Frog   752 --------------YADQEKS-----------------KKLHE---------------------- 763

  Fly   925 QEQNLVKEEDRMRDIIFQLKQEVDGKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKI-LC 988
                |...:||..    |.:|::.|.:..:.:|.:.::|||....          |:..|:: ..
 Frog   764 ----LTVMQDRRE----QARQDLKGLEETVAKELQTLHNLRKLFV----------QDLTTRVKKS 810

  Fly   989 EELQTKDTVQTANKQESQEVLTLKTSLAHLKSKV------------CELQKKLEK--QSEDEKIS 1039
            .|:.:.||..:|  .:.|::..|:.:|..| :||            ||| .||||  ::..|::.
 Frog   811 AEMDSDDTGGSA--AQKQKISFLENNLEQL-TKVHKQLVRDNADLRCEL-PKLEKRLRATAERVK 871

  Fly  1040 ELQSDIGEISECCLSMELKLADIVNWQAEELRPLDQLQESGVELQHHSTTAEESLNVEKPIQ 1101
            .|:|.:.|..|.. |.:.|     .:|.|..|..:.::...:..:.||.      .:.|||:
 Frog   872 ALESALKEAKENA-SRDRK-----RYQQEVDRIKEAVRSKNMARRGHSA------QIAKPIR 921

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cana	NP_001027247.1	KISc	8..316	CDD:214526	129/332 (39%)
		Motor_domain	8..310	CDD:277568	127/326 (39%)
		SMC_prok_B	<471..1270	CDD:274008	134/665 (20%)
		Mplasa_alph_rch	924..1647	CDD:275316	44/193 (23%)
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171
kif5b	NP_001122126.1	KISc_KHC_KIF5	6..325	CDD:276820	127/326 (39%)
		Smc	<409..792	CDD:224117	105/588 (18%)
		COG4372	709..>914	CDD:226809	60/331 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000669
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910