Protein Alignment His1:CG33834 and H1-3

DIOPT Version :10

• Sequence 1: NP_001027334.1
• Gene: His1:CG33834 / 3771911
• FlyBaseID: FBgn0053834
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_005311.1
• Gene: H1-3 / 3007
• HGNCID: 4717
• Length: 221
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 101/270 - (37%)
• Similarity: 122/270 - (45%)
• Gaps: 64/270 - (23%)

  Fly     1 MSDSAVATSASPVAAPPATVEKKVGQKKASGSAGTKAKKASATPSHPPTQQMGDASIKNLKERGG 65
            ||::|......|..|....|:||.  |||..:||  .:|||.    ||..::...::...|||.|
Human     1 MSETAPLAPTIPAPAEKTPVKKKA--KKAGATAG--KRKASG----PPVSELITKAVAASKERSG 57

  Fly    66 SSLLAIKKYITAT-YKCDAQKLAPFIKKYLKSAVVNGKLIQTKGKGASGSFKLS-ASAKKEKDPK 128
            .||.|:||.:.|. |  |.:|....||..|||.|..|.|:||||.||||||||: .:|..|..||
Human    58 VSLAALKKALAAAGY--DVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPK 120

  Fly   129 AKSKVLSAEKKVQSKKVASKKIGVSSKKTAVGAADKKPKAKKAVATKKTAENKKTEKAK------ 187
            |                  ||.|.:..:...||| ||||.....||.|.:..|..:|.|
Human   121 A------------------KKAGAAKPRKPAGAA-KKPKKVAGAATPKKSIKKTPKKVKKPATAA 166

  Fly   188 -----AKDAKKTGIIKSKPAA-TKAKVTAAKPKAVIAKASKAKPAVSAKPKKTVKKASVSATAKK 246
                 ||.|||....:.|.|| :.||..|.||||       |||. |.|||.|
Human   167 GTKKVAKSAKKVKTPQPKKAAKSPAKAKAPKPKA-------AKPK-SGKPKVT------------ 211

  Fly   247 PKAKTTAAKK 256
             |||..|.||
Human   212 -KAKKAAPKK 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
His1:CG33834	NP_001027334.1	H15	43..130	CDD:238028	39/88 (44%)
H1-3	NP_005311.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		18/49 (37%)
		H15	35..115	CDD:238028	39/85 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	90..221		64/171 (37%)