Protein Alignment His1:CG33834 and H1-8

DIOPT Version :10

• Sequence 1: NP_001027334.1
• Gene: His1:CG33834 / 3771911
• FlyBaseID: FBgn0053834
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_722575.1
• Gene: H1-8 / 132243
• HGNCID: 18463
• Length: 346
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 76/293 - (25%)
• Similarity: 123/293 - (41%)
• Gaps: 41/293 - (13%)

  Fly     1 MSDSAVATSASPVAAPPATVEKKVGQKKASGSAG---TKAKKASATP---SHPPTQQMGDASIKN 59
            |:..:|.:..||.:...|...:....:|...|.|   ......|:.|   .|||..:|...:::.
Human     1 MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQA 65

  Fly    60 LKERGGSSLLAIKKYITATY-KCDAQKLAPFIKKYLKSAVVNGKL---IQTKGKGASGSFKLSAS 120
            .::|.|:|:.|||.||...| ..|..:....:|:.|.:.:..|.|   :.:|.:||:|||||...
Human    66 GEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPK 130

  Fly   121 AKKEKDPKAKSKVLSAEKKVQSKKVASKK----------IGVSSKKTAVGAADKKPKAKKAVATK 175
            .||:..|:..:...:..:..::|....||          :|...|.....|..:||..|...||:
Human   131 HKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATE 195

  Fly   176 KTAEN---KKTEKAKAKDAKKTGIIKSKP------------AATKAKVTAAKPKAVIAKASKAKP 225
            |..:.   .|..:|::.:|:|   :..||            .:.|||...::.....|:|.:...
Human   196 KARKQGGAAKDTRAQSGEARK---VPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTK 257

  Fly   226 AVSAKPKKT---VKKASVSATAKKPKAKTTAAK 255
            |.|...|.|   ||..:.|.|.||..||..|.|
Human   258 AESKSSKPTASKVKNGAASPTKKKVVAKAKAPK 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
His1:CG33834	NP_001027334.1	H15	43..130	CDD:238028	30/93 (32%)
H1-8	NP_722575.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		10/48 (21%)
		PRK07764	<2..302	CDD:236090	75/292 (26%)
		H15	49..139	CDD:238028	29/89 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..346		46/173 (27%)
		Nuclear localization signal. /evidence=ECO:0000255	164..179		2/14 (14%)