DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adh and YMR226C

DIOPT Version :9

Sequence 1:	NP_001027266.1	Gene:	Adh / 3771877	FlyBaseID:	FBgn0000055	Length:	256	Species:	Drosophila melanogaster
Sequence 2:	NP_013953.1	Gene:	YMR226C / 855266	SGDID:	S000004839	Length:	267	Species:	Saccharomyces cerevisiae

Alignment Length:	259	Identity:	71/259 - (27%)
Similarity:	107/259 - (41%)	Gaps:	49/259 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LTNKNVIFVAGLGGIGLDTSKELLKR---DLKNLVILDRIENPAAIAELKAI------NPKVTVT 60
            |..|.|:......|||..|:.|.|:.   |:|.::...|:|.   :.|||..      |.||.|.
Yeast    11 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEK---LEELKKTIDQEFPNAKVHVA 72

  Fly    61 FYPYDVTVPIAETTK-LLKTIFAQLKTVDVLINGA---------GILDDHQIERTIAVNYTGLVN 115
              ..|:|.  ||..| .::.:..:.|.:|:|:|.|         |.:....|:.....|.|.|:|
Yeast    73 --QLDITQ--AEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALIN 133

  Fly   116 TTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYT 180
            .|.|:|..:..:..|.   |.|:||:.|.:|.....:|..:|.||..||.||.|....|.:....
Yeast   134 ITQAVLPIFQAKNSGD---IVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVIL 195

  Fly   181 VNPGITRT--TLV-------HTFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKAIELNQNGAI 235
            :.||:..|  :||       ...|.:.|..|.:|:.:           |:..|.|....||..|
Yeast   196 IAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDV-----------ADLIVYATSRKQNTVI 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	70/256 (27%)
YMR226C	NP_013953.1	SDR_c5	14..266	CDD:187604	70/256 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR42901
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010