Protein Alignment Adh and HPGD

DIOPT Version :9

• Sequence 1: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_000851.2
• Gene: HPGD / 3248
• HGNCID: 5154
• Length: 266
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 67/249 - (26%)
• Similarity: 118/249 - (47%)
• Gaps: 24/249 - (9%)

  Fly     7 NKNVIFVAGLG-GIGLDTSKELLKRDLKNLVILD-----RIENPAAIAELKAINPKVTVTFYPYD 65
            |..|..|.|.. |||...::.||.:..| :.::|     .::..||:.|  ...|:.|: |...|
Human     4 NGKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDE--QFEPQKTL-FIQCD 64

  Fly    66 VT--VPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILDFWDKRK 128
            |.  ..:.:|.:.:...|.:|   |:|:|.||:.::...|:|:.:|...:::.|...||:..|:.
Human    65 VADQQQLRDTFRKVVDHFGRL---DILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQN 126

  Fly   129 GGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVNPGITRTTLV 191
            ||.||||.|:.|:.|...:.|.|||..:|..:|.||.|.|..|.:  :||....:.||...|.::
Human   127 GGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAIL 191

  Fly   192 HT------FNSWLDVEPQVAEKLLAHPTQPSLACAENFVKAIELNQ-NGAIWKL 238
            .:      ...:::.:..:.:.:..:........|...:..||.:. ||||.|:
Human   192 ESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKI 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	66/248 (27%)
HPGD	NP_000851.2	ADH_SDR_c_like	6..254	CDD:187584	66/247 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.700