Protein Alignment Adh and Hsd17b13

DIOPT Version :10

• Sequence 1: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001009684.1
• Gene: Hsd17b13 / 305150
• RGDID: 1359553
• Length: 300
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 68/268 - (25%)
• Similarity: 108/268 - (40%)
• Gaps: 66/268 - (24%)

  Fly    11 IFVAGLG-GIGLDTSKELLKRDLKNLVILD----RIENPAA-IAELKAINPKVTVTFYPYDVTVP 69
            :.:.|.| |||..|:.|..|:. ..||:.|    .:|..|| ..:|.|:     |..:..|.: .
  Rat    39 VLITGAGHGIGRLTAYEFAKQK-SRLVLWDISKHGVEETAAKCRKLGAV-----VHVFVVDCS-N 96

  Fly    70 IAETTKLLKTIFAQLKTVDVLINGAGIL--------DDHQIERTIAVNYTGLVNTTTAILDFWDK 126
            .||..|.:..:..::..:::::|.||.:        .|.:|.:|..||..|......|:|....:
  Rat    97 RAEIYKSVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLR 161

  Fly   127 RKGGPGGIICNIGSVTGFNAI-YQVPVYSGTKAAVVNFTSSLAK--------------LAPITGV 176
            |..|.   |..:.||.|...| |.:| |..:|.|.|.|..:|..              |.|:...
  Rat   162 RNSGH---IVTVASVCGHRVIPYLIP-YCSSKFAAVGFHRALTAELDTLGKTGIKTSCLCPVFVN 222

  Fly   177 TAYTVNPGITRTTLVHTFNSWLDVEP-QVA----------EKLLAHPTQPSLAC------AENFV 224
            |.:|.||. ||.        |..:|| :||          :|::..|:..:::.      .|..:
  Rat   223 TGFTKNPS-TRL--------WPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVL 278

  Fly   225 KAIELNQN 232
            |||...||
  Rat   279 KAINRIQN 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	68/268 (25%)
Hsd17b13	NP_001009684.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	63/257 (25%)