Protein Alignment Adh and Hsd17b11

DIOPT Version :10

• Sequence 1: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_001004209.1
• Gene: Hsd17b11 / 289456
• RGDID: 1303235
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 218
• Identity: 59/218 - (27%)
• Similarity: 90/218 - (41%)
• Gaps: 23/218 - (10%)

  Fly    10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAET 73
            ::.:.|.| |||..|:.|..|.:.| ||:.|..:|  .|.|..|...|:....:|:.|.....|.
  Rat    38 IVLITGAGHGIGRLTAYEFAKLNTK-LVLWDINKN--GIEETAAKCRKLGAQVHPFVVDCSQREE 99

  Fly    74 T-KLLKTIFAQLKTVDVLINGAGIL--------DDHQIERTIAVNYTGLVNTTTAILDFWDKRKG 129
            . ..::.:..::..|.:|:|.||::        .|.|||:|..||......||.|.|....|...
  Rat   100 IYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNH 164

  Fly   130 GPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNF----TSSLAKLAPITGVTAYTVNPGITRTTL 190
            |.   :..:.|..|...:..:..|..:|.|.|.|    |..||.|. .|||....:.|....|..
  Rat   165 GH---VVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALG-CTGVRTSCLCPNFINTGF 225

  Fly   191 VH--TFNSWLDVEPQVAEKLLAH 211
            :.  :.|....:||:...:.|.|
  Rat   226 IKNPSTNLGPTLEPEEVVEHLMH 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	59/218 (27%)
Hsd17b11	NP_001004209.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	59/218 (27%)