Protein Alignment Adh and RDH10

DIOPT Version :10

• Sequence 1: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Sequence 2: NP_742034.1
• Gene: RDH10 / 157506
• HGNCID: 19975
• Length: 341
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 65/265 - (24%)
• Similarity: 96/265 - (36%)
• Gaps: 61/265 - (23%)

  Fly    10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIE------------------NPAAIAELKAIN- 54
            |..:.|.| |:|...:.|..:|  :.|::|..|.                  ..|..|.|:|.|
Human    38 VCLITGAGSGLGRLFALEFARR--RALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNG 100

  Fly    55 -----PKVTVTFYPYDVTVPIAETTKL-LKTIFAQLKTVDVLINGAGILDDHQ--------IERT 105
                 |...:..:.|...|...|...| .:.:..::..|.||:|.||::..|.        ||||
Human   101 EEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERT 165

  Fly   106 IAVNYTGLVNTTTAILDFWDKRKGGP------GGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFT 164
            :.||......||.|.|         |      .|.|..:.|..|..:...|..|..:|..||.|.
Human   166 MMVNCHAHFWTTKAFL---------PTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFH 221

  Fly   165 SSLA---KLAPITGVTAYTVNPGITRTTLVHTFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKA 226
            .||:   |.|...|:....|.|.:..|.:........::||      ...|.:|.. |.:..:||
Human   222 ESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEP------FLPPLKPDY-CVKQAMKA 279

  Fly   227 IELNQ 231
            |..:|
Human   280 ILTDQ 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	65/265 (25%)
RDH10	NP_742034.1	17beta-HSDXI-like_SDR_c	38..307	CDD:187598	65/265 (25%)