DRSC/TRiP Functional Genomics Resources

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Protein Alignment Adh and Hpgd

DIOPT Version :9

Sequence 1:NP_001027266.1 Gene:Adh / 3771877 FlyBaseID:FBgn0000055 Length:256 Species:Drosophila melanogaster
Sequence 2:NP_032304.2 Gene:Hpgd / 15446 MGIID:108085 Length:269 Species:Mus musculus


Alignment Length:253 Identity:69/253 - (27%)
Similarity:120/253 - (47%) Gaps:32/253 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 NKNVIFVAGLG-GIGLDTSKELLKRDLKNLVILD-----RIENPAAIAELKAINPKVTVTFYPYD 65
            |..|..|.|.. |||...::.||....| :.::|     .::..||:.|  ...|:.|: |...|
Mouse     4 NGKVALVTGAAQGIGKAFAEALLLHGAK-VALVDWNLEAGVKCKAALDE--QFEPQKTL-FVQCD 64

  Fly    66 VT--VPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQIERTIAVNYTGLVNTTTAILDFWDKRK 128
            |.  ..:.:|.:.:...|.:|   |:|:|.||:.::...|:|:.:|...:::.|...||:..|:.
Mouse    65 VADQKQLRDTFRKVVDHFGRL---DILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQN 126

  Fly   129 GGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVNPGITRTTLV 191
            ||.||||.|:.|:.|...:.|.|||..:|..::.||.|.|..|.:  :||....:.||...|.::
Mouse   127 GGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPIL 191

  Fly   192 HT------FNSWLDVEPQVAEKL----LAHPTQPSLACAENFVKAIELNQ-NGAIWKL 238
            .:      ...:::.:.|:...:    :.||:    ..|...:..||.:. ||||.|:
Mouse   192 ESIEKEENMGQYIEYKDQIKAMMKFYGVLHPS----TIANGLINLIEDDALNGAIMKI 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdhNP_001027266.1 ADH_SDR_c_like 8..247 CDD:187584 68/252 (27%)
HpgdNP_032304.2 ADH_SDR_c_like 6..254 CDD:187584 68/251 (27%)
adh_short 6..199 CDD:278532 57/199 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167841501
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4169
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
54.700

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