Protein Alignment His3:CG33830 and H3-3B

DIOPT Version :10

• Sequence 1: NP_001027328.1
• Gene: His3:CG33830 / 3771792
• FlyBaseID: FBgn0053830
• Length: 136
• Species: Drosophila melanogaster
• Sequence 2: NP_005315.1
• Gene: H3-3B / 3021
• HGNCID: 4765
• Length: 136
• Species: Homo sapiens
• Alignment Length: 502
• Identity: 101/502 - (20%)
• Similarity: 168/502 - (33%)
• Gaps: 157/502 - (31%)

  Fly   125 LCVHCDSIYH------KECVQSPFKIEHPYHPEHSLQLSYLDLNARIMECFCCGRRATYLVYYCT 183
            :|.|.::|::      .|.:.:..|.......:|::.              ||         |..
Human   828 MCNHLENIHNFFQCLGAEHLSADDKARATAQEQHTMA--------------CC---------YQK 869

  Fly   184 ICDVLMHTVCAMKSIPLGGFHELENNGKLFFVYHHPKY----QPIPQTKSPSSDKTAN--HDLP- 241
            :..|| |.:.|.|.......|.|.::. |..:.:..|.    ||:.:..|.|.....|  |.:|
Human   870 LLQVL-HALFAWKGFTHQSKHRLLHSA-LEVLSNRLKQMEQDQPLEELVSQSFSYLQNFHHSVPS 932

  Fly   242 FQ-PLFLCPHLRVTKNSSDSLTYPISYSPEYIVSTTKSDEDLSVLPLFWCN-----NKEFNVDGG 300
            || .|:|   ||:.....:....| :...|.:.|..|     .:|...|.:     |..|| |..
Human   933 FQCGLYL---LRLLMALLEKSAVP-NQKKEKLASLAK-----QLLCRAWPHGEKEKNPTFN-DHL 987

  Fly   301 CDICSGSNFGTDYYFCVYCDKIYH----------KECVQSP---ISIKHPYHPEHSLQLSYRLPS 352
            .|:.        |.:..:.|.:..          .|.|.:|   .|...|....|:..:.:|:..
Human   988 HDVL--------YIYLEHTDNVLKAIEEITGVGVPELVSAPKDAASSTFPTLTRHTFVIFFRVMM 1044

  Fly   353 A---PDIECLCCGTTATDLVYGCTICEAVMHTPCAMKSIPFVIDQPKSHDHSL---TLFPRQASL 411
            |   ..::.|..||.|                           |..:.|:..|   .:..|..|:
Human  1045 AELEKTVKGLQAGTAA---------------------------DSQQVHEEKLLYWNMAVRDFSI 1082

  Fly   412 TCNVCGLLRKNYPTF-VCLRC--NFVAH--KDCMYSPHIIKISRHHHRISYTASLQSEEWS---- 467
            ..|:..:. .:||.. |||:.  .||..  |.||   .::..|...||....:.||:.:.:
Human  1083 LLNLMKVF-DSYPVLHVCLKYGRRFVEAFLKQCM---PLLDFSFRKHREDVLSLLQTLQLNTRLL 1143

  Fly   468 ---CG---------------VCRKSIDGDYGAYTCEKCKDYVVHVRCALRKDVWDGV----ELEG 510
               ||               :.:||::    ...| :.|..:|...|  |:..|.|.    :|:|
Human  1144 HHLCGHSKIRQDTRLTKHVPLLKKSLE----LLVC-RVKAMLVLNNC--REAFWLGTLKNRDLQG 1201

  Fly   511 VPEEDDITKDVGPFEIISE----GVILHFLHDHHLQLEVSILYDEEK 553
               |:.|::|....|..:|    ||..|...:...:.......||:|
Human  1202 ---EEIISQDPSSSESNAEDSEDGVTSHVSRNRATEDGEDEASDEQK 1245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
His3:CG33830	NP_001027328.1	PTZ00018	1..136	CDD:185400	3/16 (19%)
H3-3B	NP_005315.1	PTZ00018	1..136	CDD:185400
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43