DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18003 and hao2

DIOPT Version :9

Sequence 1:	NP_001027401.1	Gene:	CG18003 / 3771779	FlyBaseID:	FBgn0061356	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	XP_012812532.1	Gene:	hao2 / 595012	XenbaseID:	XB-GENE-979509	Length:	381	Species:	Xenopus tropicalis

Alignment Length:	368	Identity:	179/368 - (48%)
Similarity:	247/368 - (67%)	Gaps:	14/368 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALVCVEDFEKKAVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIF 65
            |:|:|:.|||..|...|.|...:||.:||.|..|...|.:||||:|||||.|||||.:|..|.:.
Frog    26 MSLICLADFEAYAKEHLPKATWEYYAAGADECCTRDDNLQAFRRIRLRPRMLRDVSVMDTKTTVL 90

  Fly    66 GEQMQWPLGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLY 130
            ||::..|:||||||...:|.||||:..||||.....:::.||.:|.|:|:::..||:.::|||||
Frog    91 GEEISCPIGIAPTAFHCLAWPDGEMSTARAAEALKLLYVASTYATCSVEEISEAAPEGLRWFQLY 155

  Fly   131 IYKDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQGVKATGVGNA 195
            :|:||.::|:|:||.|...|||||||:|.|..|.||.|:||||.||.||.:.||:||
Frog   156 VYRDRKLSEQLIRRVEALGFKALVLTVDVPYTGKRRTDIRNNFRLPPHLKVKNFEGV-------- 212

  Fly   196 AMGASGINEY--VSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGLIVSNHG 258
            ..|..|.:.|  ..:..||:::||||.||:.:|.||||:||:||.|||.||..:|..|:||||||
Frog   213 FEGHGGPDNYGVPLNTLDPSVSWKDICWLRSVTSLPIVIKGILTKEDAELAVVYGVQGIIVSNHG 277

  Fly   259 ARQIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGRPAVWGLAYNGQ 323
            .||:|...|:|:||.|||:.|...:.|.|||||..|:|:.||:|||||.||:|||.||||.|.|:
Frog   278 GRQLDGELATIDALAEIVEVVQGRIEVYLDGGIRTGSDVLKAIALGAKCVFLGRPIVWGLTYKGE 342

  Fly   324 KGVEEMLSVLRKDFETTMALIGCQNLGDITSAMVVHESQYAKL 366
            :||:.:|.:|..:|..:|||.||:|:.::...::    ..|||
Frog   343 EGVKGILQILTDEFRLSMALSGCRNVSEVNRNLI----HVAKL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18003	NP_001027401.1	alpha_hydroxyacid_oxid_FMN	7..353	CDD:239203	173/347 (50%)
CG18003	NP_001027401.1	FMN_dh	17..359	CDD:279418	169/343 (49%)
hao2	XP_012812532.1	alpha_hydroxyacid_oxid_FMN	32..373	CDD:239203	173/348 (50%)
hao2	XP_012812532.1	FMN_dh	39..377	CDD:279418	169/349 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	356	1.000	Domainoid score	I982
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	364	1.000	Inparanoid score	I2119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500918at33208
OrthoFinder	1	1.000	-	-		FOG0001123
OrthoInspector	1	1.000	-	-		otm47660
Panther	1	1.100	-	-	O	PTHR10578
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X693
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160